Validations Queue

116,327 candidate doc → node links pending adjudication. Each was auto-generated by cosine similarity ≥ 0.55 between document and prediction embeddings (bge-base-en-v1.5, 768-dim). Showing page 478 of 539, 200 rows by similarity. Adjudicating updates doc_node_links.reviewed=true with the chosen polarity, writes per-link rows to audit_log, and removes the row from this queue. Phase 4 inference will use confirmed corroborates/contradicts links as Bayesian evidence.

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SimDocSourcePredDomainPrior
0.57polymarket
2026-05-05
231_018
Blitz will switch to next generation model in late March 2026.
Dave Blundin
AI30%
0.57manifold
2026-05-05
232_013
Recursive self-improvement loops likely to go live in the next 12 months; 2026 will be the most consequential year for humanity.
Jimmy Ba
AI47%
0.57edgar_8k
2026-05-05
CMQ_053
Figure AI secured $675M Series B in 2024 and partnered commercially with BMW — addressing skilled-labor shortages in automotive manufacturing.
Brett Adcock
Robotics55%
0.57edgar_8k
2026-05-05
COD_AI_001
Vera Rubin becomes commercially available across major cloud and OEM partners by H2 2026
Codex Research Pack
Technology51%
0.57edgar_8k
2026-05-04
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.57
FDA NDA011525: IC-GREEN (INDOCYANINE GREEN) — RENEW PHARMS
fda
2026-04-22
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.57
FDA ANDA210273: MULTIPLE VITAMINS INJECTION ADULT (ALPHA-TOCOPHEROL ACETATE) — APOTEX
fda
2026-04-09
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.57
FDA ANDA210672: MULTIPLE VITAMINS INJECTION ADULT (ALPHA-TOCOPHEROL ACETATE) — APOTEX
fda
2026-04-09
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.57
FDA ANDA218738: GLYCEROL PHENYLBUTYRATE (GLYCEROL PHENYLBUTYRATE) — TEVA PHARMS INC
fda
2026-04-15
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA ANDA205105: METHYLPHENIDATE HYDROCHLORIDE (METHYLPHENIDATE HYDROCHLORIDE) — IMPAX LABS INC
fda
2026-04-21
SEM_026
Nvidia's next 'Rubin' product cycle is the most critical factor for semi industry in coming year — further integrates logic + HBM.
Joseph Moore
Semis/Products62%
0.57
FDA ANDA090169: LAMOTRIGINE (LAMOTRIGINE) — GLENMARK PHARMS LTD
fda
2026-04-10
248_030
FDA will be first government agency forced to get out of the way; government must accelerate regulation speed thousands of times.
Dave Blundin
Geopolitics50%
0.57
FDA ANDA090170: LAMOTRIGINE (LAMOTRIGINE) — UNICHEM LABS LTD
fda
2026-04-09
SEM_026
Nvidia's next 'Rubin' product cycle is the most critical factor for semi industry in coming year — further integrates logic + HBM.
Joseph Moore
Semis/Products62%
0.57
FDA ANDA206371: OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE (HYDROCHLOROTHIAZIDE) — MICRO LABS
fda
2026-04-13
CMQ_038
Micron has initiated HVM production of HBM4 36GB module delivering 2.8 TB/s bandwidth — optimized to reduce 'time to first token' for long-context LLM inference.
Micron
Semis/Memory52%
0.57
FDA BLA125514: KEYTRUDA (PEMBROLIZUMAB) — MERCK SHARP DOHME
fda
2026-06-24
TK13
Biotech/Synbio Safety Event
15%
0.57
FDA ANDA219409: ALBUTEROL SULFATE (ALBUTEROL SULFATE) — CIPLA
fda
2026-04-22
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.57github_release
2025-10-01
AUT_012
True AGI arrives 2030-2035 (5-10 years from 2026) based on advanced 'world model systems' — current LLM architecture insufficient for generalized autonomy due to lack of temporal consistency and deep reasoning; world models inherently understand/simula...
Demis Hassabis
AI38%
0.57github_release
2025-08-13
235_005
AI capability will grow 100x this year in raw parameter count as lower bound.
Dave Blundin
AI49%
0.57github_release
2025-06-04
229_028
Figure will NOT license out its neural net or hardware IP to third-party form-factor builders.
Brett Adcock
Robotics69%
0.57github_release
2023-05-08
IND_005
Convergence of computational biology + AI-driven data modeling + CRISPR gene editing enables bringing back extinct species — Form Bio platform (spun out 2022) enables successful resurrection of woolly mammoth and Tasmanian tiger within the decade (by ~...
Ben Lamm
Biotech/Longevity33%
0.57github_release
2022-12-16
240_016
Everyone is underestimating the next year of AI improvements (more than 2x gain)
Dave Blundin
AI36%
0.57github_release
2023-08-29
S_HUMANOID_CONSUMER_2030
Humanoid R3: 1M+ consumer by Nov 2030
humanoid_deployment20%
0.57github_release
2020-06-12
CYB_029
Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by Anthropic's April 2026 ban of OpenClaw) — this structural conflict highlights the precarious nature of building autonomous enterprises atop proprietary APIs,...
Anthropic
AI80%
0.57github_release
2020-05-22
CYB_009
Hardware-software alignment will force widespread foundational-codebase rewrites — exemplified by Midjourney's strategic migration from Google TPU architecture to native GPU framework, enabling hyper-fast personalization, HD generation, and massive par...
David Holz
AI77%
0.57polymarket
2026-05-05
229_005
The global humanoid robotics industry will consolidate to far fewer than 10 players.
Brett Adcock
Robotics15%
0.57polymarket
2026-05-03
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks36%
0.57
Ducks vs. Golden Knights(market prob: 41%)
polymarket
2026-05-03
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.57polymarket
2025-06-19
235_027
Longevity VC market expected to grow from $8.5B in 2024 to $12-18B in 2026.
Peter Diamandis
Biotech/Longevity38%
0.57polymarket
2026-04-20
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets53%
0.57arxiv
2026-05-05
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.57arxiv
2026-05-04
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.57arxiv
2026-05-05
241_019
AI scaling laws have not hit an asymptote yet
Eric Schmidt
AI51%
0.57arxiv
2026-05-04
231_004
The solution wavefront will spread from math/coding to physics, chemistry, and other fields.
Alex Wissner-Gross
AI40%
0.57arxiv
2026-05-04
231_004
The solution wavefront will spread from math/coding to physics, chemistry, and other fields.
Alex Wissner-Gross
AI40%
0.57
FDA ANDA211482: DAPAGLIFLOZIN (DAPAGLIFLOZIN) — AJANTA PHARMA LTD
fda
2026-04-06
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA ANDA219540: GLYCEROL PHENYLBUTYRATE (GLYCEROL PHENYLBUTYRATE) — MSN
fda
2026-04-15
CMQ_010
True AGI requires genuine scientific-discovery capabilities (AlphaFold-class breakthroughs) — brute-force LLM scaling alone is insufficient.
Demis Hassabis
AI49%
0.57
FDA ANDA219540: GLYCEROL PHENYLBUTYRATE (GLYCEROL PHENYLBUTYRATE) — MSN
fda
2026-04-15
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA ANDA220660: ELTROMBOPAG OLAMINE (ELTROMBOPAG OLAMINE) — AIZANT
fda
2026-04-28
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA ANDA220788: SODIUM BICARBONATE (SODIUM BICARBONATE) — ASPIRO
fda
2026-04-15
245_009
Breaking plastic-degradation technology could become a supplement that breaks microplastics in the gut before absorption
Peter Diamandis
Biotech/Longevity45%
0.57
FDA ANDA211560: DAPAGLIFLOZIN (DAPAGLIFLOZIN) — ALEMBIC
fda
2026-04-06
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA BLA761068: CRYSVITA (BUROSUMAB-TWZA) — KYOWA KIRIN
fda
2026-04-23
CMQ_037
Samsung will grow global HBM market share from 20% to 28% by securing majority of orders for Vera Rubin-exclusive HBM4.
Morgan Stanley
Semis/Memory20%
0.57
Knicks vs. 76ers(market prob: 40%)
polymarket
2026-05-03
235_025
Nvidia's margins unsustainable; cracks in armor but all chips made will sell.
Dave Blundin
Markets/Stocks32%
0.57
Spurs vs. Timberwolves(market prob: 67%)
polymarket
2026-05-02
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI37%
0.57polymarket
2026-05-04
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.57polymarket
2026-05-07
FUT_012
Two-thirds of world's nations reaching tipping point 2026-2031 where building new renewable capacity is strictly cheaper than operating existing fully-depreciated coal/natural gas facilities — achieved completely independent of government subsidies. De...
Ramez Naam
Energy45%
0.57polymarket
2025-11-14
236_011
Independent/third party presidential run possible in 2028 election
Andrew Yang
Geopolitics46%
0.57manifold
2026-05-07
242_033
Companies will race to 80% token spend / 20% salary; good by 2030-2032
Dave Blundin
Labor/Jobs49%
0.57manifold
2026-05-06
238_036
Manus (bought by Meta for $2B) will become Meta's agent layer inside WhatsApp, operating on behalf of advertisers
Emad Mostaque
Media/Ads25%
0.57manifold
2026-05-06
248_044
Alex: likely user ~1 million of a BCI implant (not 101) once upgradeable.
Alex Wissner-Gross
Biotech/Longevity39%
0.57arxiv
2026-05-06
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.57
FDA ANDA202949: DULOXETINE HYDROCHLORIDE (DULOXETINE HYDROCHLORIDE) — ALEMBIC
fda
2026-04-09
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.57github_release
2025-11-03
247_057
Parameter scaling race is over; frontier labs plateauing at 10T parameters
Alex Wissner-Gross
AI18%
0.57
Thunder vs. Lakers(market prob: 77%)
polymarket
2026-05-03
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.57polymarket
2026-05-02
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.57polymarket
2026-01-04
241_042
Post-tragedy, global leaders (US, China) will convene on AI governance
Eric Schmidt
Geopolitics44%
0.57polymarket
2025-07-11
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.57arxiv
2026-05-07
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.57arxiv
2026-05-07
CMQ_055
Multimodal voice recognition powered by generative AI will serve as the default user interface for humanoid physical workers — speak instructions, robot executes.
Brett Adcock
Robotics31%
0.57arxiv
2026-05-07
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.57arxiv
2026-05-07
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.57arxiv
2026-05-06
CYB_023
Immutable cryptographic verification layers — specifically Bitcoin — must be integrated into AI architectures as decentralized ground-truth anchor: establishing undeniable digital provenance in an ecosystem inevitably flooded with AI-generated data, de...
Michael Saylor
Crypto26%
0.57arxiv
2026-05-07
232_056
Every single discipline (math, physics, chemistry, medicine) will be flattened by well-targeted generalist AIs.
Alex Wissner-Gross
AI40%
0.57arxiv
2026-05-06
231_004
The solution wavefront will spread from math/coding to physics, chemistry, and other fields.
Alex Wissner-Gross
AI40%
0.57polymarket
2026-05-04
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.57polymarket
2026-05-04
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.57polymarket
2026-05-04
CMQ_037
Samsung will grow global HBM market share from 20% to 28% by securing majority of orders for Vera Rubin-exclusive HBM4.
Morgan Stanley
Semis/Memory20%
0.57polymarket
2026-05-04
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.57polymarket
2026-03-24
232_021
No chance AI will be paused in the next three years given current administration and China competition.
Dave Blundin
Geopolitics75%
0.57
Knicks vs. 76ers(market prob: 52%)
polymarket
2026-05-04
235_025
Nvidia's margins unsustainable; cracks in armor but all chips made will sell.
Dave Blundin
Markets/Stocks32%
0.57manifold
2026-05-09
240_002
Amazon or Anthropic will hit a trillion in revenue within a calendar year faster than NVIDIA
Dave Blundin
Markets/Stocks29%
0.57polymarket
2026-05-08
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.57manifold
2026-05-10
230_034
Abundance will be achieved by 2035.
Peter Diamandis
Macro/Economy41%
0.57polymarket
2026-05-10
FUT_019
Global market rapidly accelerates bio-industrial circumvention of fractured supply chains 2026-2031: combination of Webb agentic LAMs overseeing vast bio-reactors powered by sub-cent-per-kWh solar energy creates highly-localized completely-autonomous i...
Multi-Forecaster Synthesis
Biotech/Longevity31%
0.57polymarket
2026-05-05
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.57polymarket
2026-05-02
TK06
China-Taiwan Military Conflict
8%
0.57polymarket
2026-05-02
231_018
Blitz will switch to next generation model in late March 2026.
Dave Blundin
AI30%
0.57polymarket
2025-07-03
247_025
Super PACs will determine election outcomes at order of magnitude bigger than before
Dave Blundin
Geopolitics29%
0.57polymarket
2025-11-14
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.57polymarket
2026-05-08
229_005
The global humanoid robotics industry will consolidate to far fewer than 10 players.
Brett Adcock
Robotics15%
0.57edgar_8k
2026-05-11
FUT_019
Global market rapidly accelerates bio-industrial circumvention of fractured supply chains 2026-2031: combination of Webb agentic LAMs overseeing vast bio-reactors powered by sub-cent-per-kWh solar energy creates highly-localized completely-autonomous i...
Multi-Forecaster Synthesis
Biotech/Longevity31%
0.57edgar_8k
2026-05-11
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.57edgar_8k
2026-05-11
S_GRID_50GW_2027
50GW dedicated AI/data center grid by Dec 2027
energy_grid_expansion40%
0.57github_release
2024-09-16
S_ROBOTAXI_TESLA_2026
Tesla FSD unsupervised wide deployment by Nov 2026
robotaxi_deployment40%
0.57github_release
2023-08-04
S_ROBOTAXI_TESLA_2026
Tesla FSD unsupervised wide deployment by Nov 2026
robotaxi_deployment40%
0.57
Sabres vs. Canadiens(market prob: 42%)
polymarket
2026-05-08
231_025
Every frontier lab will launch 24/7 agent offerings (table stakes).
Alex Wissner-Gross
AI41%
0.57polymarket
2026-05-12
TK06
China-Taiwan Military Conflict
8%
0.57polymarket
2026-05-06
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.57polymarket
2026-05-11
247_010
Anthropic will beat OpenAI in valuation trajectory
Dave Blundin
AI40%
0.57polymarket
2025-09-15
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.57polymarket
2026-02-09
243_001
Autonomous vehicle market will develop in a hybrid way, not binary all-or-nothing
Dara Khosrowshahi
Auto/Transport44%
0.57polymarket
2026-05-11
231_045
Corporations will start downplaying AI capabilities to avoid antitrust backlash.
Dave Blundin
AI41%
0.57edgar_8k
2026-05-12
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.57edgar_8k
2026-05-12
247_003
Settlement will include granting equity stake on OpenAI cap table for Elon in ultimate IPO
Alex Wissner-Gross
AI35%
0.57edgar_8k
2026-05-12
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.57github_release
2025-12-11
234_048
Next major revolutions in foundation models will come from small language models
Alex Wissner-Gross
AI41%
0.57github_release
2025-04-09
234_004
Mistral will emerge as a vertically integrated European OpenAI
Alex Wissner-Gross
AI35%
0.57github_release
2024-08-05
CYB_029
Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by Anthropic's April 2026 ban of OpenClaw) — this structural conflict highlights the precarious nature of building autonomous enterprises atop proprietary APIs,...
Anthropic
AI80%
0.57polymarket
2026-05-07
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.57polymarket
2026-05-07
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.57edgar_8k
2026-05-13
240_026
Elon's combined empire (SpaceX/xAI/Tesla/Optimus/Terrafab/orbital DCs) will be a $100T company
Dave Blundin
Markets/Stocks14%
0.57edgar_8k
2026-05-13
247_001
xAI will IPO at $2 trillion valuation this coming summer
Peter Diamandis
AI42%
0.57polymarket
2026-04-30
241_027
China will win low-end robotic hardware race
Eric Schmidt
Robotics49%
0.57
Golden Knights vs. Ducks(market prob: 51%)
polymarket
2026-05-11
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI37%
0.57polymarket
2026-01-02
230_032
Near future will see multiple spheres of influence each independently locking itself in (geopolitically).
Alex Wissner-Gross
Geopolitics39%
0.57polymarket
2026-05-13
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.57polymarket
2026-05-10
235_045
Most volume in e-commerce and physical world will eventually be dominated by algorithms (like quantitative trading).
Alex Wissner-Gross
Consumer42%
0.57manifold
2026-05-14
240_045
White House to disclose something about aliens/UAPs in the next few months (rumors of June/July/summer)
Alex Wissner-Gross
Geopolitics29%
0.57edgar_8k
2026-05-14
CMQ_053
Figure AI secured $675M Series B in 2024 and partnered commercially with BMW — addressing skilled-labor shortages in automotive manufacturing.
Brett Adcock
Robotics55%
0.57edgar_8k
2026-05-14
SEM_028
Main characters for semi institutional portfolios: Nvidia, Broadcom, and high-growth connectivity firms like Astera Labs.
Joseph Moore
Capital Markets55%
0.57edgar_8k
2026-05-14
TK10
$100T Sovereign Debt Crisis
12%
0.57edgar_8k
2026-05-14
SEM_028
Main characters for semi institutional portfolios: Nvidia, Broadcom, and high-growth connectivity firms like Astera Labs.
Joseph Moore
Capital Markets55%
0.57
FDA BLA761032: SILIQ (BRODALUMAB) — VALEANT LUXEMBOURG
fda
2026-05-07
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA ANDA205402: PALIPERIDONE (PALIPERIDONE) — I3 PHARMS
fda
2026-05-07
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.57
FDA ANDA204982: PHENTERMINE HYDROCHLORIDE AND TOPIRAMATE (PHENTERMINE HYDROCHLORIDE) — ACTAVIS LABS FL INC
fda
2026-05-01
CMQ_010
True AGI requires genuine scientific-discovery capabilities (AlphaFold-class breakthroughs) — brute-force LLM scaling alone is insufficient.
Demis Hassabis
AI49%
0.57
FDA ANDA207740: OMEPRAZOLE (OMEPRAZOLE) — DR REDDYS
fda
2026-04-29
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.57github_release
2025-05-23
237_018
We are seeing a Cambrian explosion of OpenClaw variants (PicoClaw, IronClaw, NanoClaw, Nanobot, etc.) with many more to come.
Alex Wissner-Gross
AI40%
0.57polymarket
2026-04-29
229_001
Figure will put robots on its own manufacturing lines (BotQ) this year to build robots.
Brett Adcock
Robotics39%
0.57polymarket
2026-04-29
246_014
Elon's stated orbital refueling and Mars/Moon timelines will slip.
Alex Wissner-Gross
Space41%
0.57manifold
2026-05-15
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.57arxiv
2026-05-14
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.57arxiv
2026-05-14
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.57
FDA ANDA078625: LAMOTRIGINE (LAMOTRIGINE) — RUBICON RESEARCH
fda
2026-05-12
SEM_026
Nvidia's next 'Rubin' product cycle is the most critical factor for semi industry in coming year — further integrates logic + HBM.
Joseph Moore
Semis/Products62%
0.57
FDA NDA219531: SDAMLO (AMLODIPINE BESYLATE) — BRILLIAN PHARMA
fda
2026-05-08
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.57
FDA BLA761034: TECENTRIQ (ATEZOLIZUMAB) — GENENTECH INC
fda
2026-05-15
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.57polymarket
2026-05-10
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.57polymarket
2026-04-19
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks36%
0.57manifold
2026-05-16
235_011
PE fund will emerge shortly to buy medium/big companies and install AI digital twin infrastructure.
Salim Ismail
Markets/Stocks47%
0.57manifold
2026-05-16
231_005
Next year frontier reasoning costs will be pennies (down from ~$7 now).
Peter Diamandis
AI55%
0.57manifold
2026-05-16
234_019
Expect big AI capability improvements via recursive self-improvement over next few weeks
Alex Wissner-Gross
AI24%
0.57manifold
2026-05-16
231_038
TSMC fabs will come online in 5-6-7 years; Elon won't wait that long.
Dave Blundin
AI44%
0.57manifold
2026-05-15
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.57manifold
2026-05-14
242_050
Humanoid robots will be over-engineered but will unlock supply chain
Dave Blundin
Robotics42%
0.57
FDA NDA212728: NURTEC ODT (RIMEGEPANT SULFATE) — PFIZER
fda
2026-05-08
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.57
FDA NDA021732: VANTAS (HISTRELIN ACETATE) — ENDO OPERATIONS
fda
2026-05-06
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.57github_release
2022-12-21
248_037
State data-center moratoriums will accelerate Dyson-swarm / orbital compute innovation due to constriction.
Alex Wissner-Gross
AI14%
0.57github_release
2022-12-21
CYB_029
Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by Anthropic's April 2026 ban of OpenClaw) — this structural conflict highlights the precarious nature of building autonomous enterprises atop proprietary APIs,...
Anthropic
AI80%
0.57github_release
2022-12-08
CYB_029
Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by Anthropic's April 2026 ban of OpenClaw) — this structural conflict highlights the precarious nature of building autonomous enterprises atop proprietary APIs,...
Anthropic
AI80%
0.57github_release
2020-11-18
CMQ_047
Autonomous code agents and AutoResearch systems will close the loop on complex scientific experimentation without human-in-the-loop.
Andrej Karpathy
AI51%
0.57github_release
2020-09-20
AI_025
Most current generative AI wrappers are transient — they will fade into the background as infrastructure layers, analogous to Radio Shack fading in the Windows/PC era; winners will be infrastructure and verticalized depth plays, not thin API-wrapper apps.
Mark Cuban
AI60%
0.57github_release
2020-08-18
242_051
Dyson swarm compute infrastructure will be realized in a few years
Alex Wissner-Gross
Space24%
0.57github_release
2020-07-18
CYB_029
Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by Anthropic's April 2026 ban of OpenClaw) — this structural conflict highlights the precarious nature of building autonomous enterprises atop proprietary APIs,...
Anthropic
AI80%
0.57polymarket
2026-05-11
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.57polymarket
2026-05-16
CMQ_036
SK Hynix will maintain industry HBM lead, capturing >50% of NVIDIA's total HBM procurement (HBM3E + HBM4) throughout 2026.
Morgan Stanley
Semis/Memory68%
0.57polymarket
2026-05-17
233_009
A motivational learning bundle with video game designers will be released in 2026.
Joe Liemandt
Education36%
0.57manifold
2026-05-17
247_006
Anthropic ARR will reach $100 billion by end of 2026
Peter Diamandis
AI50%
0.57
Cavaliers vs. Knicks(market prob: 33%)
polymarket
2026-05-18
238_028
Anthropic plugins will enable market-by-market disruption (could short stocks and announce plugins)
Emad Mostaque
Markets/Stocks31%
0.57polymarket
2026-05-15
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets53%
0.57polymarket
2025-07-16
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.57polymarket
2025-08-04
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets53%
0.57
Spread: Thunder (-5.5)(market prob: 55%)
polymarket
2026-05-18
TK10
$100T Sovereign Debt Crisis
12%
0.57polymarket
2026-02-05
229_020
By end of 2026, Figure will be able to drop a robot into an unseen home and do fairly long-horizon work.
Brett Adcock
Robotics20%
0.57polymarket
2025-07-03
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.57manifold
2026-05-18
COD_SPC_002
The next US crewed lunar surface landing occurs on Artemis IV in 2028
Codex Research Pack
Space22%
0.57edgar_8k
2026-05-18
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.57edgar_8k
2026-05-18
CYB_022
Supply-chain attacks targeting widely utilized open-source AI packages — exemplified by documented attacks on the LiteLLM framework — represent extreme systemic risk: a single compromised foundational code repository instantly and autonomously infects ...
Alex Wissner-Gross
AI76%
0.57polymarket
2025-09-11
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.57
FDA ANDA219750: L-GLUTAMINE (L-GLUTAMINE) — STIRA
fda
2026-05-14
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity40%
0.57
FDA ANDA218691: CEFIXIME (CEFIXIME) — FDC LTD
fda
2026-05-14
248_030
FDA will be first government agency forced to get out of the way; government must accelerate regulation speed thousands of times.
Dave Blundin
Geopolitics50%
0.57polymarket
2026-05-25
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets53%
0.57polymarket
2026-05-29
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.57polymarket
2026-04-23
246_025
Sam Altman predicts world-shaking cyber attack this year (2026).
Sam Altman
AI47%
0.57polymarket
2026-02-20
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks36%
0.57polymarket
2026-02-28
FUT_008
China ceases to exist as functional unified economic superpower within next 10 years — terminal horizon ~2036 with severe undeniable systemic degradation fully visible 2026-2031. Unique-compromised demographic pyramid (One-Child Policy + fastest urbani...
Peter Zeihan
Geopolitics30%
0.57polymarket
2026-05-25
FUT_022
Massive resurgence in North American industrialization 2026-2031 driven by geographic + demographic insulation of United States + Mexico — permanent systemic withdrawal from trans-Pacific and trans-Atlantic economic dependencies; aggressive 'de-risking...
Peter Zeihan
Macro/Economy72%
0.57polymarket
2026-02-28
FUT_015
Era of 'multipolarity without multilateralism' defining 2026-2031 per Eurasia Group + WEF Global Risks Report — power highly distributed among regional hegemons but international cooperation mechanisms (UN, WTO) functionally collapsed. Exacerbated by '...
Ian Bremmer
Geopolitics62%
0.57polymarket
2026-05-30
246_006
OpenAI will IPO by end of 2026, Anthropic early-to-mid 2027 (may try end of 2026).
Peter Diamandis
Markets/Stocks37%
0.57polymarket
2026-04-16
FUT_008
China ceases to exist as functional unified economic superpower within next 10 years — terminal horizon ~2036 with severe undeniable systemic degradation fully visible 2026-2031. Unique-compromised demographic pyramid (One-Child Policy + fastest urbani...
Peter Zeihan
Geopolitics30%
0.57manifold
2026-05-30
246_031
Next OpenClaw moment will turn $30B ARR into $1T ARR with agents.
Alex Wissner-Gross
AI35%
0.57manifold
2026-05-30
235_005
AI capability will grow 100x this year in raw parameter count as lower bound.
Dave Blundin
AI49%
0.57manifold
2026-05-29
AI_001
AI will surpass peak human intelligence across ALL economically valuable domains by 2030, extending the sequential maturation roadmap beyond 'independent researcher' (2028) into full-domain superintelligence.
Sam Altman
AI33%
0.57manifold
2026-05-29
241_029
Humanoid robot assembly of rockets is beyond current robots for a long time
Eric Schmidt
Robotics12%
0.57manifold
2026-05-28
248_010
AI capabilities will advance 100x in 2026 (by summer, potentially more).
Dave Blundin
AI20%
0.57manifold
2026-05-27
231_016
Permissionless agent activity is imminent; Claude-style approval prompts will go away.
Alex Wissner-Gross
AI41%
0.57manifold
2026-05-27
240_043
CS placements collapsed from 89% to 19% over 3 years; similar collapse coming for other professions
Peter Diamandis
Labor/Jobs55%
0.57manifold
2026-05-25
247_001
xAI will IPO at $2 trillion valuation this coming summer
Peter Diamandis
AI42%
0.57manifold
2026-05-24
233_009
A motivational learning bundle with video game designers will be released in 2026.
Joe Liemandt
Education36%
0.57manifold
2026-05-24
243_005
There will be many many winners in the autonomous space
Dara Khosrowshahi
Auto/Transport47%
0.57arxiv
2026-05-28
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.57arxiv
2026-05-28
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.57arxiv
2026-05-28
AUT_017
Defining 2023-2026 shift: maturation of 'Agentic AI' via heavy fine-tuning of pre-trained LLMs using advanced reinforcement learning techniques — single foundational models seamlessly handling diverse complex tasks (market analysis, software engineerin...
Jimmy Ba
AI65%
0.57arxiv
2026-05-28
231_004
The solution wavefront will spread from math/coding to physics, chemistry, and other fields.
Alex Wissner-Gross
AI40%
0.57arxiv
2026-05-28
234_048
Next major revolutions in foundation models will come from small language models
Alex Wissner-Gross
AI41%
0.57arxiv
2026-05-28
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.57
FDA ANDA211035: VERAPAMIL HYDROCHLORIDE (VERAPAMIL HYDROCHLORIDE) — SOMERSET
fda
2026-05-20
CMQ_035
HBM4 16-layer stack design (required for Vera Rubin) places unprecedented yield and capacity strain on global memory fabrication facilities.
Jensen Huang / Morgan Stanley
Semis/Memory68%
0.57polymarket
2026-05-29
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.57manifold
2026-05-31
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.57manifold
2026-05-31
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.57polymarket
2026-05-16
229_025
Competitors that can match Figure's current capabilities are at least two years behind.
Brett Adcock
Robotics46%
0.57
Spread: Spurs (-4.5)(market prob: 52%)
polymarket
2026-05-31
235_016
SpaceX IPO anticipated potentially as early as next month (April 2026).
Peter Diamandis
Space31%
0.57polymarket
2026-05-16
237_013
Over 12-24 months value created by consumer adoption of OpenClaw will outweigh corporate destruction.
Alex Finn
Macro/Economy43%
0.57polymarket
2026-05-31
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.57polymarket
2026-05-26
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI37%
0.57polymarket
2026-05-26
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets53%
0.57polymarket
2026-01-08
232_021
No chance AI will be paused in the next three years given current administration and China competition.
Dave Blundin
Geopolitics75%
0.57polymarket
2026-05-16
CMQ_041
Reallocation of foundry real estate toward high-margin HBM leaves severe unaddressed supply shortage for traditional consumer-grade DRAM — bifurcation of global memory market.
Morgan Stanley
Semis/Memory71%
0.57polymarket
2025-11-12
248_010
AI capabilities will advance 100x in 2026 (by summer, potentially more).
Dave Blundin
AI20%
0.57polymarket
2025-11-25
247_018
First version of social contract will be politicians writing checks in next election
Dave Blundin
Macro/Economy46%
0.57manifold
2026-06-01
S_GRID_50GW_2027
50GW dedicated AI/data center grid by Dec 2027
energy_grid_expansion40%
0.57manifold
2026-06-01
236_011
Independent/third party presidential run possible in 2028 election
Andrew Yang
Geopolitics46%
0.57manifold
2026-05-31
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.57edgar_8k
2026-06-01
SEM_028
Main characters for semi institutional portfolios: Nvidia, Broadcom, and high-growth connectivity firms like Astera Labs.
Joseph Moore
Capital Markets55%