Validations Queue

94,964 candidate doc → node links pending adjudication. Each was auto-generated by cosine similarity ≥ 0.55 between document and prediction embeddings (bge-base-en-v1.5, 768-dim). Showing page 276 of 441, 200 rows by similarity. Adjudicating updates doc_node_links.reviewed=true with the chosen polarity, writes per-link rows to audit_log, and removes the row from this queue. Phase 4 inference will use confirmed corroborates/contradicts links as Bayesian evidence.

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Confirm or label (corroborates / contradicts) all unreviewed links above a similarity threshold in one transaction. Each affected row writes a per-link audit_log entry. Capped at 1,000 links per call. Use Preview first.

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SimDocSourcePredDomainPrior
0.60
FDA NDA020941: ABREVA (DOCOSANOL) — HALEON US HOLDINGS
fda
2026-04-14
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.60github_release
2026-04-17
INF_009
The first multi-behavior brain-organoid upload is imminent — wetware ('brain organoid') computing has progressed from Pong (2021) to Doom-class simulators (2025), and offers a pathway out of silicon thermal limits at ~20W per brain-equivalent compute.
Alex Wissner-Gross
AI17%
0.60polymarket
2025-07-08
S_RECESSION_2027
NBER recession declared 2027
macro_recession30%
0.60manifold
2026-05-07
229_026
By next year (2027), Figure expects to show real general purpose capability inside the robot; possibly within months.
Brett Adcock
Robotics38%
0.60manifold
2026-05-07
247_006
Anthropic ARR will reach $100 billion by end of 2026
Peter Diamandis
AI50%
0.60
will i get gold at amm 2026(market prob: 78%)
manifold
2026-05-07
233_009
A motivational learning bundle with video game designers will be released in 2026.
Joe Liemandt
Education36%
0.60arxiv
2026-05-06
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.60arxiv
2026-05-06
232_007
TikTok wins as AI enables personalized, movie-quality content in many languages, taking over from movie industry.
Dave Blundin
Media/Ads45%
0.60arxiv
2026-05-06
AUT_020
AI-driven adaptive learning platforms operating with near-total autonomy — human teachers transition from content deliverers to motivational 'guides' while AI handles entirety of core academic instruction. Short highly-focused 'Pomodoro' sessions manag...
MacKenzie Price
Education49%
0.60arxiv
2026-05-06
238_071
Future AI models may compress all human knowledge into megabytes via post-transformer breakthroughs
Alex Wissner-Gross
AI35%
0.60arxiv
2026-05-05
248_023
Ternary (sub-bit) parameter precision will be optimal for AI models.
Dave Blundin
AI50%
0.60
FDA ANDA217477: ANDA217477 ((unspecified)) — HAINAN POLY PHARM. CO., LTD.
fda
2026-04-23
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.60github_release
2019-04-05
CMQ_044
Future data-center architectures optimized for agentic workflows may require 1:2 or even 2:1 CPU-to-GPU ratio (vs historical 1:12) to prevent GPU idle-waiting.
Morgan Stanley
AI/Compute65%
0.60github_release
2026-03-03
239_003
We are currently in AI hard takeoff
Elon Musk
AI47%
0.60github_release
2025-12-19
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.60github_release
2024-10-04
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.60github_release
2025-12-02
242_044
Base AI models becoming commodity; value migrates up the stack
Alex Wissner-Gross
AI35%
0.60github_release
2024-12-31
236_028
AI chatbot/AI romance trend growing unfortunately
Andrew Yang
Consumer51%
0.60github_release
2024-10-22
SEM_022
FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed nations maintain competitive development.
Dave Blundin
AI/Architecture65%
0.60github_release
2024-07-25
248_048
AI models will move to a post-binary (sub-one-bit) numerical precision paradigm.
Alex Wissner-Gross
AI34%
0.60
Pistons vs. Cavaliers(market prob: 40%)
polymarket
2026-05-04
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.60
Thunder vs. Lakers(market prob: 77%)
polymarket
2026-05-03
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.60polymarket
2025-10-09
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.60manifold
2026-05-08
SEM_009
The AI boom rooted in semiconductor hardware will generate the world's first individual trillionaire (2026+).
Mark Cuban
Economy30%
0.60arxiv
2026-05-07
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.60arxiv
2026-05-07
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60arxiv
2026-05-07
CMQ_055
Multimodal voice recognition powered by generative AI will serve as the default user interface for humanoid physical workers — speak instructions, robot executes.
Brett Adcock
Robotics29%
0.60arxiv
2026-05-07
CYB_005
'Memory becomes the moat' — by 2026, the global discourse around 'AI safety' will effectively transition into highly politicized debates over 'memory policy'. Whichever entity controls the contextual history and relational memory of human-AI interactio...
Ray Kurzweil
AI30%
0.60arxiv
2026-05-07
AUT_010
As models transition from passive advisors to active multi-step task executors across digital networks, potential for catastrophic systemic failure scales exponentially — without rigorous legislative oversight + embedded algorithmic surveillance, auton...
Daniella Amodei
AI56%
0.60arxiv
2026-05-07
247_050
Virtual cell achievable through classical scaling without quantum computing
Alex Wissner-Gross
Biotech/Longevity44%
0.60arxiv
2026-05-07
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.60arxiv
2026-05-07
CYB_011
Consumer commerce shifts from 'search and click' to 'ask and buy' — persistent AI agents with hyper-personalized memory navigate budgetary limits, ethical brand preferences, dietary restrictions, and logistical requirements with absolute precision, sev...
Alex Finn
Consumer44%
0.60arxiv
2026-05-07
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.60arxiv
2026-05-07
AI_029
Blockchain provenance protocols will be increasingly applied to enterprise workflows to detect deepfakes and verify the authenticity of AI model outputs — positioning cryptographic content-authentication as a mandatory enterprise trust layer.
Morgan Stanley
AI57%
0.60arxiv
2026-05-07
CYB_015
The human hiring process becomes progressively distorted as autonomous bot agents actively screen resumes generated by other bot agents, completely removing the human connection required to accurately assess contextual experience — bot-on-bot recursive...
Emad Mostaque
Labor/Jobs86%
0.60arxiv
2026-05-07
CYB_023
Immutable cryptographic verification layers — specifically Bitcoin — must be integrated into AI architectures as decentralized ground-truth anchor: establishing undeniable digital provenance in an ecosystem inevitably flooded with AI-generated data, de...
Michael Saylor
Crypto26%
0.60arxiv
2026-05-07
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.60arxiv
2026-05-07
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.60arxiv
2026-05-06
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.60arxiv
2026-05-06
242_043
AI models will distill down to a few million parameters as end-state
Alex Wissner-Gross
AI35%
0.60arxiv
2026-05-06
242_008
Dyson sphere will come before any fusion reactor is licensed
Dave Blundin
Energy40%
0.60arxiv
2026-05-06
241_019
AI scaling laws have not hit an asymptote yet
Eric Schmidt
AI51%
0.60polymarket
2026-05-05
IND_016
By late 2026, SpaceX will launch a flotilla of approximately 5 uncrewed Starships to the Martian surface — success relies entirely on autonomous orbital refilling + AI-driven landing telemetry, proving precursor infrastructure for human colonization ca...
Gwynne Shotwell
Space27%
0.60manifold
2026-05-09
AUT_024
H1 2026 will deliver a 'massive AI breakthrough' driven by unprecedented concentration of computational power at leading American laboratories — AI has been elevated from mere thematic investment to structural 'macro variable' akin to oil prices or int...
Morgan Stanley
AI42%
0.60edgar_8k
2026-05-08
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.60manifold
2026-05-10
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.60polymarket
2025-10-09
236_011
Independent/third party presidential run possible in 2028 election
Andrew Yang
Geopolitics46%
0.60polymarket
2026-05-11
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.60manifold
2026-05-11
241_042
Post-tragedy, global leaders (US, China) will convene on AI governance
Eric Schmidt
Geopolitics44%
0.60manifold
2026-05-11
TK10
$100T Sovereign Debt Crisis
12%
0.60edgar_8k
2026-05-11
CMQ_028
NVIDIA's total AI chip revenue opportunity through 2027 is at least $3-5 trillion (upgraded from prior estimates at MS TMT 2026).
Jensen Huang
Semis72%
0.60github_release
2025-04-11
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.60github_release
2025-03-05
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.60polymarket
2026-04-27
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.60polymarket
2026-05-12
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.60manifold
2026-05-12
SEM_035
World-class, AI-based mathematicians will emerge within a single year (by ~early 2027).
Eric Schmidt
AI/Cognition45%
0.60manifold
2026-05-12
S_IPO_TRILLION_2027
First $1T+ IPO in 2027
ipo_trillion_plus40%
0.60manifold
2026-05-12
INF_048
Global data-center energy demand will reach approximately 945 Terawatt-hours by 2030 — a roughly 175% increase from 2023 levels — requiring complete grid overhauls in major markets.
IEA
Energy48%
0.60edgar_8k
2026-05-12
CMQ_040
AI-driven demand has triggered an 'unprecedented supercycle' for dominant global memory suppliers (Samsung, SK Hynix, Micron).
Samsung executives
Semis/Memory62%
0.60edgar_8k
2026-05-12
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.60edgar_8k
2026-05-12
TK02
AI Compute Supply Shock (TSMC/Taiwan Disruption)
12%
0.60edgar_8k
2026-05-12
TK10
$100T Sovereign Debt Crisis
12%
0.60
FDA ANDA200217: LORAZEPAM (LORAZEPAM) — RISING
fda
2026-05-04
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.60polymarket
2026-05-13
237_017
The entire SaaS market is going to zero because features can be rebuilt in five minutes with agents.
Alex Finn
Markets/Stocks45%
0.60polymarket
2026-05-11
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.60polymarket
2026-05-13
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.60polymarket
2026-05-13
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.60polymarket
2026-05-12
TK06
China-Taiwan Military Conflict
8%
0.60polymarket
2026-05-04
238_061
Massive social unrest / trough in 2026-2027, rebound in 2028
Dave Blundin
Macro/Economy50%
0.60manifold
2026-05-13
230_040
AI capability/accuracy will improve recursively; output-checking issues will be eliminated quickly.
Peter Diamandis
AI50%
0.60arxiv
2026-05-12
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.60arxiv
2026-05-12
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.60arxiv
2026-05-12
AUT_010
As models transition from passive advisors to active multi-step task executors across digital networks, potential for catastrophic systemic failure scales exponentially — without rigorous legislative oversight + embedded algorithmic surveillance, auton...
Daniella Amodei
AI56%
0.60arxiv
2026-05-12
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.60arxiv
2026-05-12
AI_025
Most current generative AI wrappers are transient — they will fade into the background as infrastructure layers, analogous to Radio Shack fading in the Windows/PC era; winners will be infrastructure and verticalized depth plays, not thin API-wrapper apps.
Mark Cuban
AI60%
0.60arxiv
2026-05-12
SPC_025
Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every one AGI safety researcher — extreme systemic risk as these autonomous systems are deployed into physical domains like space and embodied robotics.
Leopold Aschenbrenner
AI64%
0.60arxiv
2026-05-12
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.60arxiv
2026-05-12
CYB_009
Hardware-software alignment will force widespread foundational-codebase rewrites — exemplified by Midjourney's strategic migration from Google TPU architecture to native GPU framework, enabling hyper-fast personalization, HD generation, and massive par...
David Holz
AI77%
0.60arxiv
2026-05-12
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.60arxiv
2026-05-12
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.60github_release
2026-05-13
240_021
Post-transformer architecture will be even more specialized than GPUs
Alex Wissner-Gross
AI35%
0.60polymarket
2025-05-02
246_039
Autonomous vehicles/flying cars coming by 2028.
Peter Diamandis
Auto/Transport34%
0.60polymarket
2026-05-04
238_061
Massive social unrest / trough in 2026-2027, rebound in 2028
Dave Blundin
Macro/Economy50%
0.60polymarket
2026-05-11
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.60polymarket
2026-05-04
238_061
Massive social unrest / trough in 2026-2027, rebound in 2028
Dave Blundin
Macro/Economy50%
0.60manifold
2026-05-13
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.60edgar_8k
2026-05-14
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.60arxiv
2026-05-13
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.60arxiv
2026-05-13
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.60arxiv
2026-05-13
SPC_017
Startups capable of cleaning, structuring, and validating multimodal data pipelines (video, telemetry, Earth-observation) will unlock enterprise value of space-based observations — unstructured multimodal data causes AI agent workflows to hallucinate o...
Jennifer Li
AI63%
0.60arxiv
2026-05-13
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60arxiv
2026-05-13
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.60arxiv
2026-05-13
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.60arxiv
2026-05-13
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.60arxiv
2026-05-13
SEM_022
FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed nations maintain competitive development.
Dave Blundin
AI/Architecture65%
0.60polymarket
2025-07-28
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.60polymarket
2026-05-11
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.60manifold
2026-05-15
232_044
There will be police agents, defense agents, and public health agents monitoring rogue AI agents via defensive co-scaling.
Alex Wissner-Gross
AI42%
0.60manifold
2026-05-12
242_037
China will land on the moon before end of 2030
China (government)
Space46%
0.60edgar_8k
2026-05-15
TK02
AI Compute Supply Shock (TSMC/Taiwan Disruption)
12%
0.60arxiv
2026-05-14
CYB_023
Immutable cryptographic verification layers — specifically Bitcoin — must be integrated into AI architectures as decentralized ground-truth anchor: establishing undeniable digital provenance in an ecosystem inevitably flooded with AI-generated data, de...
Michael Saylor
Crypto26%
0.60arxiv
2026-05-14
CMQ_043
In complex Agentic AI workloads, CPU-side processing accounts for 50-90% of end-to-end latency — validating CPU-bottleneck shift empirically.
Morgan Stanley / Georgia Tech / Intel
AI/Compute92%
0.60arxiv
2026-05-14
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60arxiv
2026-05-14
ROB_025
Genomic prediction will be entirely revolutionized by high-throughput phenotyping — utilizing swarms of drones and physical robots to collect orders of magnitude more trait information than historically possible by human scientists; Bayesian optimizati...
Peter Dannenberg
Biotech/Longevity70%
0.60arxiv
2026-05-14
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.60arxiv
2026-05-14
TK01
AGI Capability Plateau (2026-27 Training Stall)
15%
0.60arxiv
2026-05-14
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.60arxiv
2026-05-13
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.60
FDA NDA212576: INQOVI (CEDAZURIDINE) — TAIHO ONCOLOGY
fda
2026-05-13
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.60polymarket
2025-10-09
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.60polymarket
2025-10-09
AUT_022
2026 is the definitive 'inflection year' for Autonomous Vehicles — forecasting 33 distinct consumer AV launches and expansion of AV services into 9 new major US cities; China will aggressively lead global adoption, accounting for half the global smart-...
Morgan Stanley
Auto/Transport47%
0.60polymarket
2026-05-11
S_AGI_WINTER_2036PLUS
AGI delayed: capability plateau or AI winter
agi_general_capability10%
0.60polymarket
2026-05-05
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.60polymarket
2026-05-15
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.60manifold
2026-05-16
S_AI_PAUSE_2027
AI pause beginning 2027
ai_regulatory_pause10%
0.60manifold
2026-05-16
244_032
Uber will cash flow $10B this year (2026)
Dara Khosrowshahi
Markets/Stocks55%
0.60manifold
2026-05-16
238_048
US must find 100 GW of new power or lose AI race to China (cited from Eric Schmidt)
Eric Schmidt
Geopolitics45%
0.60
FDA NDA210308: YONSA (ABIRATERONE ACETATE) — SUN PHARM
fda
2026-05-13
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.60
FDA ANDA200880: ACETAZOLAMIDE SODIUM (ACETAZOLAMIDE SODIUM) — MYLAN ASI
fda
2026-05-07
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.60github_release
2021-06-10
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.60polymarket
2026-05-11
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.60manifold
2026-05-17
238_005
By September 2026 there will be 1000+ ultra-high-inspirational-quality videos of the future generated nearly free
Alex Wissner-Gross
AI39%
0.60manifold
2026-05-17
241_048
AI/LLM will be the expression platform for student art, music, writing
Eric Schmidt
Education51%
0.60manifold
2026-05-17
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks50%
0.60manifold
2026-05-17
246_032
Claude or successors will be granted limited form of AI personhood.
Alex Wissner-Gross
AI35%
0.60manifold
2026-05-16
SEM_025
Morgan Stanley price target $250 for Nvidia — representing 32% upside from current levels.
Joseph Moore
Capital Markets55%
0.60
Spread: Thunder (-5.5)(market prob: 55%)
polymarket
2026-05-18
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.60polymarket
2026-05-09
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.60manifold
2026-05-18
235_008
Anthropic/OpenAI will be forced to release first-party OpenClaw competitor in next couple months.
Alex Wissner-Gross
AI42%
0.60manifold
2026-05-18
S_AI_PAUSE_2027
AI pause beginning 2027
ai_regulatory_pause10%
0.60manifold
2026-05-18
246_004
SpaceX will come out at $2T and run up very quickly to $3T.
Peter Diamandis
Markets/Stocks50%
0.60manifold
2026-05-18
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.60edgar_8k
2026-05-18
CMQ_040
AI-driven demand has triggered an 'unprecedented supercycle' for dominant global memory suppliers (Samsung, SK Hynix, Micron).
Samsung executives
Semis/Memory62%
0.60github_release
2026-05-18
CMQ_015
Algorithmic efficiencies will deliver ~0.5 OOMs per year of additional effective compute through 2027 — pure multiplier on raw FLOPs.
Leopold Aschenbrenner
AI50%
0.60github_release
2026-05-18
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.60manifold
2026-05-19
235_006
By end of 2026 AI will enable creating any virus or nuclear weapon via AI agent.
Dave Blundin
AI50%
0.60manifold
2026-05-19
236_047
New emotional pandemic of fear and anger coming
Peter Diamandis
Macro/Economy55%
0.60manifold
2026-05-19
242_023
World will have 10x more wealth around 2034-2036
Dave Blundin
Macro/Economy34%
0.60manifold
2026-05-18
AUT_024
H1 2026 will deliver a 'massive AI breakthrough' driven by unprecedented concentration of computational power at leading American laboratories — AI has been elevated from mere thematic investment to structural 'macro variable' akin to oil prices or int...
Morgan Stanley
AI42%
0.60manifold
2026-05-18
SEM_032
15% probability that AI will solve a Clay Mathematics Institute Millennium Prize problem (likely Navier-Stokes) by end of 2026.
Alex Wissner-Gross
AI/Mathematics15%
0.60arxiv
2026-05-18
IND_003
Latency of medical truth actively collapsing — genomic sequencing for newborns in neonatal intensive care units (NICUs) reduced to a 4-hour window, effectively moving diagnostics from 'wait and see' paradigm to real-time intervention; convergence of ph...
Alex Wissner-Gross
Biotech/Longevity46%
0.60arxiv
2026-05-18
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.60arxiv
2026-05-18
233_021
AI learning will improve via closed-loop reinforcement learning cycle making results keep increasing.
Joe Liemandt
AI39%
0.60arxiv
2026-05-18
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.60arxiv
2026-05-18
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.60arxiv
2026-05-18
CMQ_038
Micron has initiated HVM production of HBM4 36GB module delivering 2.8 TB/s bandwidth — optimized to reduce 'time to first token' for long-context LLM inference.
Micron
Semis/Memory52%
0.60arxiv
2026-05-18
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.60arxiv
2026-05-18
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.60arxiv
2026-05-18
229_044
Positive transfer learning will continue to emerge, meaning more diverse data makes Figure robots broadly better at many tasks.
Brett Adcock
AI35%
0.60arxiv
2026-05-18
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.60arxiv
2026-05-18
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60polymarket
2025-07-28
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.60manifold
2026-05-30
S_ROBOTAXI_MASS_2030
Robotaxi >10% urban miles by Nov 2030
robotaxi_deployment30%
0.60manifold
2026-05-30
S_ROBOTAXI_MASS_2030
Robotaxi >10% urban miles by Nov 2030
robotaxi_deployment30%
0.60manifold
2026-05-28
241_008
AI research agents will be limited only by electricity, with potentially millions possible
Eric Schmidt
AI43%
0.60manifold
2026-05-27
FUT_012
Two-thirds of world's nations reaching tipping point 2026-2031 where building new renewable capacity is strictly cheaper than operating existing fully-depreciated coal/natural gas facilities — achieved completely independent of government subsidies. De...
Ramez Naam
Energy45%
0.60manifold
2026-05-27
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.60manifold
2026-05-27
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.60manifold
2026-05-25
229_044
Positive transfer learning will continue to emerge, meaning more diverse data makes Figure robots broadly better at many tasks.
Brett Adcock
AI35%
0.60manifold
2026-05-25
229_005
The global humanoid robotics industry will consolidate to far fewer than 10 players.
Brett Adcock
Robotics36%
0.60edgar_8k
2026-05-29
TK02
AI Compute Supply Shock (TSMC/Taiwan Disruption)
12%
0.60arxiv
2026-05-28
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.60arxiv
2026-05-28
IND_003
Latency of medical truth actively collapsing — genomic sequencing for newborns in neonatal intensive care units (NICUs) reduced to a 4-hour window, effectively moving diagnostics from 'wait and see' paradigm to real-time intervention; convergence of ph...
Alex Wissner-Gross
Biotech/Longevity46%
0.60arxiv
2026-05-28
IND_014
Generative AI has rendered static one-size-fits-all learning structurally obsolete — 'every textbook is obsolete' as AI tutors construct personalized lessons mapped perfectly to student mastery level; total disintermediation of the human academic teach...
Joe Liemandt
Education48%
0.60arxiv
2026-05-28
SPC_017
Startups capable of cleaning, structuring, and validating multimodal data pipelines (video, telemetry, Earth-observation) will unlock enterprise value of space-based observations — unstructured multimodal data causes AI agent workflows to hallucinate o...
Jennifer Li
AI63%
0.60arxiv
2026-05-28
CMQ_015
Algorithmic efficiencies will deliver ~0.5 OOMs per year of additional effective compute through 2027 — pure multiplier on raw FLOPs.
Leopold Aschenbrenner
AI50%
0.60arxiv
2026-05-28
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.60arxiv
2026-05-28
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.60arxiv
2026-05-28
SPC_025
Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every one AGI safety researcher — extreme systemic risk as these autonomous systems are deployed into physical domains like space and embodied robotics.
Leopold Aschenbrenner
AI64%
0.60arxiv
2026-05-28
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.60arxiv
2026-05-28
ROB_025
Genomic prediction will be entirely revolutionized by high-throughput phenotyping — utilizing swarms of drones and physical robots to collect orders of magnitude more trait information than historically possible by human scientists; Bayesian optimizati...
Peter Dannenberg
Biotech/Longevity70%
0.60arxiv
2026-05-28
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.60arxiv
2026-05-28
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60arxiv
2026-05-28
CYB_022
Supply-chain attacks targeting widely utilized open-source AI packages — exemplified by documented attacks on the LiteLLM framework — represent extreme systemic risk: a single compromised foundational code repository instantly and autonomously infects ...
Alex Wissner-Gross
AI76%
0.60arxiv
2026-05-28
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.60arxiv
2026-05-28
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.60arxiv
2026-05-28
AI_024
As AI-generated video becomes indistinguishable from reality, a massive economic resurgence in the 'Face-to-Face' (F2F) economy will emerge — live-event production, in-person experiences, and physical gatherings rebound as synthetic-reality counterweig...
Mark Cuban
Consumer45%
0.60arxiv
2026-05-28
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60arxiv
2026-05-28
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.60arxiv
2026-05-28
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.60arxiv
2026-05-28
CMQ_043
In complex Agentic AI workloads, CPU-side processing accounts for 50-90% of end-to-end latency — validating CPU-bottleneck shift empirically.
Morgan Stanley / Georgia Tech / Intel
AI/Compute92%
0.60arxiv
2026-05-28
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.60arxiv
2026-05-27
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.60arxiv
2026-05-28
234_041
50% probability fundamental physics could be solved in the next few years
Alex Wissner-Gross
Other39%
0.60arxiv
2026-05-28
CMQ_062
Physicists are successfully demonstrating quantum interference with increasingly larger physical masses — rapid quantum-hardware advancement.
Alex Wissner-Gross
Quantum62%
0.60
FDA NDA214275: UPTRAVI (SELEXIPAG) — ACTELION
fda
2026-05-23
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.60manifold
2026-05-31
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.60manifold
2026-05-31
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.60polymarket
2025-07-06
232_021
No chance AI will be paused in the next three years given current administration and China competition.
Dave Blundin
Geopolitics75%
0.60polymarket
2026-04-06
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.60
Monaco vs. Nanterre(market prob: 100%)
polymarket
2026-05-30
247_010
Anthropic will beat OpenAI in valuation trajectory
Dave Blundin
AI40%
0.60polymarket
2026-04-24
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.60polymarket
2026-04-06
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.60polymarket
2026-04-06
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.60polymarket
2025-10-09
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.60edgar_8k
2026-06-01
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.60
FDA NDA212479: JYLAMVO (METHOTREXATE) — SHORLA
fda
2026-05-27
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.60
FDA BLA761275: TYENNE (TOCILIZUMAB-AAZG) — FRESENIUS KABI USA
fda
2026-05-21
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.60polymarket
2026-04-06
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.60arxiv
2026-06-01
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%