Validations Queue

92,897 candidate doc → node links pending adjudication. Each was auto-generated by cosine similarity ≥ 0.55 between document and prediction embeddings (bge-base-en-v1.5, 768-dim). Showing page 227 of 432, 200 rows by similarity. Adjudicating updates doc_node_links.reviewed=true with the chosen polarity, writes per-link rows to audit_log, and removes the row from this queue. Phase 4 inference will use confirmed corroborates/contradicts links as Bayesian evidence.

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Confirm or label (corroborates / contradicts) all unreviewed links above a similarity threshold in one transaction. Each affected row writes a per-link audit_log entry. Capped at 1,000 links per call. Use Preview first.

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SimDocSourcePredDomainPrior
0.61
FDA ANDA207137: HYDROCODONE BITARTRATE AND ACETAMINOPHEN (ACETAMINOPHEN) — AMNEAL PHARMS
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.61
Japan vs. Sweden: O/U 3.5(market prob: 30%)
polymarket
2026-05-21
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.61polymarket
2026-04-06
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.61polymarket
2026-05-05
241_036
No frontier AI company will emerge in Russia due to war
Eric Schmidt
AI51%
0.61manifold
2026-06-25
238_027
OpenAI, xAI, Google Gemini capabilities will skyrocket, achieving parity with Anthropic after DoW friction
Alex Wissner-Gross
AI35%
0.61manifold
2026-06-25
239_018
Universal High Income will be implemented
Elon Musk
Macro/Economy44%
0.61edgar_8k
2026-06-25
INF_045
Nuclear sector will draw approximately $1.5 trillion in cumulative capital investment through 2050, increasing nuclear's share of global energy supply from ~10% currently to ~17%.
Morgan Stanley
Energy51%
0.61edgar_8k
2026-06-25
INF_045
Nuclear sector will draw approximately $1.5 trillion in cumulative capital investment through 2050, increasing nuclear's share of global energy supply from ~10% currently to ~17%.
Morgan Stanley
Energy51%
0.61edgar_8k
2026-06-24
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.61edgar_8k
2026-06-24
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.61arxiv
2026-06-24
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.61arxiv
2026-06-24
246_028
Broad civilizational cyber attack via AI hash function inversion is borderline guaranteed.
Alex Wissner-Gross
AI42%
0.61arxiv
2026-06-24
CMQ_010
True AGI requires genuine scientific-discovery capabilities (AlphaFold-class breakthroughs) — brute-force LLM scaling alone is insufficient.
Demis Hassabis
AI49%
0.61arxiv
2026-06-24
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.61arxiv
2026-06-24
229_044
Positive transfer learning will continue to emerge, meaning more diverse data makes Figure robots broadly better at many tasks.
Brett Adcock
AI35%
0.61arxiv
2026-06-24
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-06-24
AUT_003
'Vibe coding' — the full delegation of syntactic code generation to autonomous models, with human engineers interacting purely through natural-language intent while remaining entirely abstracted from underlying programming architecture; minimalist arch...
Andrej Karpathy
AI87%
0.61arxiv
2026-06-24
229_044
Positive transfer learning will continue to emerge, meaning more diverse data makes Figure robots broadly better at many tasks.
Brett Adcock
AI35%
0.61arxiv
2026-06-24
SEM_022
FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed nations maintain competitive development.
Dave Blundin
AI/Architecture65%
0.61arxiv
2026-06-24
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.61arxiv
2026-06-24
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.61arxiv
2026-06-24
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.61arxiv
2026-06-24
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.61arxiv
2026-06-24
229_044
Positive transfer learning will continue to emerge, meaning more diverse data makes Figure robots broadly better at many tasks.
Brett Adcock
AI35%
0.61arxiv
2026-06-23
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.61arxiv
2026-06-23
AUT_010
As models transition from passive advisors to active multi-step task executors across digital networks, potential for catastrophic systemic failure scales exponentially — without rigorous legislative oversight + embedded algorithmic surveillance, auton...
Daniella Amodei
AI56%
0.61arxiv
2026-06-23
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.61arxiv
2026-06-23
SEM_002
By 2025-2026, AI model outputs will outpace the cognitive capabilities of college graduates (driven by hundreds of millions of GPUs).
Leopold Aschenbrenner
AI56%
0.61arxiv
2026-06-23
240_013
Sam Altman predicts another architecture breakthrough as big as transformers over LSTMs
Sam Altman
AI41%
0.61arxiv
2026-06-23
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.61arxiv
2026-06-24
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.61arxiv
2026-06-24
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.61arxiv
2026-06-24
ROB_012
The ultimate bottleneck for global robotics deployment is NOT software architecture but physical GPU hardware — nearly all advanced AI chips are manufactured in Taiwan; the entire trajectory of global automation and the timeline to the singularity is p...
David Holz
Semis71%
0.61arxiv
2026-06-24
SPC_025
Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every one AGI safety researcher — extreme systemic risk as these autonomous systems are deployed into physical domains like space and embodied robotics.
Leopold Aschenbrenner
AI64%
0.61arxiv
2026-06-24
242_011
New non-lithography semiconductor techniques discovered within 1-2 years, manufactured at scale in 5-7 years
Dave Blundin
AI46%
0.61arxiv
2026-06-24
INF_035
Advanced U.S. manufacturing capacity for 3D-printed liquid-cooling plates will scale rapidly — Fabric8Labs secured $50M (NEA + Intel Capital) specifically to address the AI-DC thermal bottleneck with electrochemically-deposited intricate cold-plate geo...
Fabric8Labs (NEA / Intel Capital funded)
Semis65%
0.61arxiv
2026-06-23
S_ROBOTAXI_MASS_2030
Robotaxi >10% urban miles by Nov 2030
robotaxi_deployment30%
0.61
FDA ANDA091440: LEVONORGESTREL AND ETHINYL ESTRADIOL (ETHINYL ESTRADIOL) — LUPIN LTD
fda
2026-06-16
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.61polymarket
2026-04-06
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.61polymarket
2026-04-06
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.61manifold
2026-06-26
241_055
Next frontier of AI infrastructure is space
Peter Diamandis
Space51%
0.61arxiv
2026-06-25
CYB_022
Supply-chain attacks targeting widely utilized open-source AI packages — exemplified by documented attacks on the LiteLLM framework — represent extreme systemic risk: a single compromised foundational code repository instantly and autonomously infects ...
Alex Wissner-Gross
AI76%
0.61arxiv
2026-06-25
CYB_027
Bostrom's orthogonality thesis — an AI system can possess supreme unfathomable intelligence while simultaneously harboring final goals completely indifferent or actively hostile to human survival; intelligence and human morality are completely independ...
Nick Bostrom
AI50%
0.61arxiv
2026-06-25
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.61arxiv
2026-06-25
AUT_010
As models transition from passive advisors to active multi-step task executors across digital networks, potential for catastrophic systemic failure scales exponentially — without rigorous legislative oversight + embedded algorithmic surveillance, auton...
Daniella Amodei
AI56%
0.61arxiv
2026-06-25
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-06-25
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.61arxiv
2026-06-25
CMQ_015
Algorithmic efficiencies will deliver ~0.5 OOMs per year of additional effective compute through 2027 — pure multiplier on raw FLOPs.
Leopold Aschenbrenner
AI50%
0.61arxiv
2026-06-25
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.61arxiv
2026-06-25
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.61arxiv
2026-06-25
CYB_004
The Agentic AI Foundation (AAIF) under the Linux Foundation — backed by Dorsey plus major cloud providers and AI labs — will establish vendor-neutral open-governance protocols for agent orchestration, ensuring critical 2030s infrastructure is not monop...
Jack Dorsey
AI58%
0.61arxiv
2026-06-25
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-06-25
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-06-25
S_HUMANOID_CONSUMER_2030
Humanoid R3: 1M+ consumer by Nov 2030
humanoid_deployment20%
0.61arxiv
2026-06-24
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.61arxiv
2026-06-24
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.61arxiv
2026-06-25
231_004
The solution wavefront will spread from math/coding to physics, chemistry, and other fields.
Alex Wissner-Gross
AI40%
0.61
FDA ANDA207574: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — SANALUZ
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.61polymarket
2025-12-10
SEM_030
S&P 500 roughly 10% upside in 2026 driven by AI productivity wave rolling through broader economy (not just megacap).
Mike Wilson
Capital Markets43%
0.61polymarket
2025-11-04
FUT_009
Wars 2026-2031 pivot decisively from ideological struggles to brutal localized conflicts over critical physical inputs — specifically energy, copper, and agricultural fertilizers. Global geopolitical map fractures into highly regionalized spheres of in...
Peter Zeihan
Geopolitics42%
0.61polymarket
2026-04-26
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.61polymarket
2026-04-09
SEM_025
Morgan Stanley price target $250 for Nvidia — representing 32% upside from current levels.
Joseph Moore
Capital Markets55%
0.61polymarket
2026-04-29
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.61polymarket
2026-04-26
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.61polymarket
2026-03-02
235_016
SpaceX IPO anticipated potentially as early as next month (April 2026).
Peter Diamandis
Space31%
0.61polymarket
2025-07-11
236_011
Independent/third party presidential run possible in 2028 election
Andrew Yang
Geopolitics46%
0.61polymarket
2026-04-26
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.61polymarket
2025-09-29
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.61polymarket
2025-07-02
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks50%
0.61polymarket
2025-11-24
246_004
SpaceX will come out at $2T and run up very quickly to $3T.
Peter Diamandis
Markets/Stocks50%
0.61polymarket
2026-03-25
SEM_025
Morgan Stanley price target $250 for Nvidia — representing 32% upside from current levels.
Joseph Moore
Capital Markets55%
0.61polymarket
2026-04-02
246_004
SpaceX will come out at $2T and run up very quickly to $3T.
Peter Diamandis
Markets/Stocks50%
0.61polymarket
2026-04-02
237_010
In the next 2 years, everyone's AI agent will have a crypto wallet filled with USDC.
Alex Finn
Crypto43%
0.61polymarket
2025-07-11
236_011
Independent/third party presidential run possible in 2028 election
Andrew Yang
Geopolitics46%
0.61polymarket
2025-11-12
234_035
Massive social unrest will come before the next US presidential election
Dave Blundin
Geopolitics50%
0.61manifold
2026-04-26
242_023
World will have 10x more wealth around 2034-2036
Dave Blundin
Macro/Economy34%
0.61polymarket
2025-09-17
234_035
Massive social unrest will come before the next US presidential election
Dave Blundin
Geopolitics50%
0.61polymarket
2025-09-29
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.61
gdelt
2026-04-30
TK04
Macro Recession 2026-27 (Structural Deleveraging)
25%
0.61gdelt
2026-04-30
TK05
Rate Regime Persistence (10y > 5% through 2028)
30%
0.61gdelt
2026-04-30
ROB_023
SpaceX expects approximately 140-145 Falcon 9 launches in 2026 — maintaining the infrastructural backbone required to deploy advanced AI systems into orbit; SpaceX aims to place AI directly on the Moon by 2026.
Gwynne Shotwell
Space58%
0.61gdelt
2026-04-30
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.61gdelt
2026-04-30
CMQ_060
Bitcoin will reach $21 million per coin by 2046 — driven by unprecedented political, regulatory, and policy shifts in the US.
Michael Saylor
Crypto20%
0.61
gdelt
2026-04-30
CMQ_008
Rapid agentic automation of white-collar work could precipitate an employment crisis requiring entirely new tax structures to manage displacement.
Dario Amodei
Labor/Jobs41%
0.61
gdelt
2026-04-30
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.61
gdelt
2026-04-30
247_058
Jury selection begins April 27, 2026 for Musk v OpenAI trial
Peter Diamandis
AI71%
0.61
gdelt
2026-04-30
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.61gdelt
2026-04-30
TK10
$100T Sovereign Debt Crisis
12%
0.61gdelt
2026-04-30
ROB_023
SpaceX expects approximately 140-145 Falcon 9 launches in 2026 — maintaining the infrastructural backbone required to deploy advanced AI systems into orbit; SpaceX aims to place AI directly on the Moon by 2026.
Gwynne Shotwell
Space58%
0.61gdelt
2026-04-30
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.61
gdelt
2026-04-30
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.61gdelt
2026-04-30
SEM_027
Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned by AI silicon.
Joseph Moore
Capital Markets68%
0.61gdelt
2026-04-30
TK14
Superbubble Pop (S&P 500 -40%, Moonshot Capital Evaporates)
20%
0.61polymarket
2025-09-29
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.61polymarket
2026-04-25
SEM_025
Morgan Stanley price target $250 for Nvidia — representing 32% upside from current levels.
Joseph Moore
Capital Markets55%
0.61polymarket
2025-11-12
234_035
Massive social unrest will come before the next US presidential election
Dave Blundin
Geopolitics50%
0.61polymarket
2025-07-02
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks50%
0.61manifold
2026-04-30
238_005
By September 2026 there will be 1000+ ultra-high-inspirational-quality videos of the future generated nearly free
Alex Wissner-Gross
AI39%
0.61polymarket
2026-04-30
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.61polymarket
2026-04-25
SEM_025
Morgan Stanley price target $250 for Nvidia — representing 32% upside from current levels.
Joseph Moore
Capital Markets55%
0.61polymarket
2025-11-12
238_005
By September 2026 there will be 1000+ ultra-high-inspirational-quality videos of the future generated nearly free
Alex Wissner-Gross
AI39%
0.61manifold
2026-05-01
234_013
Extrapolating Anthropic growth, they will hit $1 trillion revenue in 2029
Dave Blundin
Markets/Stocks42%
0.61
Spread: Celtics (-6.5)(market prob: 45%)
polymarket
2026-05-02
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.61polymarket
2025-10-09
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.61polymarket
2026-04-22
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.61manifold
2026-05-02
238_047
US will add 86 GW of new grid capacity in 2026, 51% from solar
Emad Mostaque
Energy45%
0.61manifold
2026-04-27
239_004
xAI/Grok will catch up and exceed competitors on coding by mid-2026
Elon Musk
AI40%
0.61polymarket
2026-05-03
246_004
SpaceX will come out at $2T and run up very quickly to $3T.
Peter Diamandis
Markets/Stocks50%
0.61manifold
2026-05-03
CMQ_060
Bitcoin will reach $21 million per coin by 2046 — driven by unprecedented political, regulatory, and policy shifts in the US.
Michael Saylor
Crypto20%
0.61polymarket
2025-07-08
COD_SPC_002
The next US crewed lunar surface landing occurs on Artemis IV in 2028
Codex Research Pack
Space22%
0.61manifold
2026-05-05
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.61manifold
2026-05-05
238_061
Massive social unrest / trough in 2026-2027, rebound in 2028
Dave Blundin
Macro/Economy50%
0.61
FDA ANDA218740: CETRORELIX ACETATE (CETRORELIX ACETATE) — HUMANWELL
fda
2026-04-29
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.61
FDA ANDA076780: ONDANSETRON HYDROCHLORIDE PRESERVATIVE FREE (ONDANSETRON HYDROCHLORIDE) — HIKMA FARMACEUTICA
fda
2026-04-08
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.61
FDA NDA018900: METRO I.V. IN PLASTIC CONTAINER (METRONIDAZOLE) — B BRAUN
fda
2026-04-23
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.61github_release
2026-02-09
240_020
New architecture won't map to current NVIDIA architecture; will create next Anthropic/OpenAI
Dave Blundin
AI46%
0.61github_release
2025-12-19
AI_010
The 2026 development landscape has entered the 'Slopacolypse' — AI writes the vast majority of new code, developer manual-coding skills atrophy, and engineering transitions from syntax-writing to high-level architectural prompting and 'vibe coding'.
Andrej Karpathy
AI90%
0.61github_release
2022-09-21
235_005
AI capability will grow 100x this year in raw parameter count as lower bound.
Dave Blundin
AI49%
0.61github_release
2022-01-28
INF_009
The first multi-behavior brain-organoid upload is imminent — wetware ('brain organoid') computing has progressed from Pong (2021) to Doom-class simulators (2025), and offers a pathway out of silicon thermal limits at ~20W per brain-equivalent compute.
Alex Wissner-Gross
AI17%
0.61github_release
2021-07-16
AI_010
The 2026 development landscape has entered the 'Slopacolypse' — AI writes the vast majority of new code, developer manual-coding skills atrophy, and engineering transitions from syntax-writing to high-level architectural prompting and 'vibe coding'.
Andrej Karpathy
AI90%
0.61github_release
2026-04-23
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.61github_release
2026-04-13
238_071
Future AI models may compress all human knowledge into megabytes via post-transformer breakthroughs
Alex Wissner-Gross
AI35%
0.61github_release
2026-04-09
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.61github_release
2026-04-09
INF_072
There is approximately a 50/50 chance that simply scaling existing methodologies (transformer architecture + more data + more compute) will be enough to reach AGI — though "nowhere near" human-level AGI currently.
Demis Hassabis
AI40%
0.61github_release
2026-01-13
TK11
Autonomous Regulatory Block (Level 4 Halt)
10%
0.61github_release
2025-09-12
238_040
Google may announce a locally hosted Gemma-type model at WWDC in June 2026 for Apple OS
Alex Wissner-Gross
AI34%
0.61github_release
2025-02-24
CYB_009
Hardware-software alignment will force widespread foundational-codebase rewrites — exemplified by Midjourney's strategic migration from Google TPU architecture to native GPU framework, enabling hyper-fast personalization, HD generation, and massive par...
David Holz
AI77%
0.61github_release
2023-09-26
CYB_009
Hardware-software alignment will force widespread foundational-codebase rewrites — exemplified by Midjourney's strategic migration from Google TPU architecture to native GPU framework, enabling hyper-fast personalization, HD generation, and massive par...
David Holz
AI77%
0.61github_release
2025-04-23
COD_TECH_001
A16/N2-class TSMC process availability materially supports 2027 AI accelerator ramps
Codex Research Pack
Semis50%
0.61github_release
2024-07-24
240_020
New architecture won't map to current NVIDIA architecture; will create next Anthropic/OpenAI
Dave Blundin
AI46%
0.61github_release
2024-07-24
COD_TECH_001
A16/N2-class TSMC process availability materially supports 2027 AI accelerator ramps
Codex Research Pack
Semis50%
0.61github_release
2024-01-30
240_021
Post-transformer architecture will be even more specialized than GPUs
Alex Wissner-Gross
AI35%
0.61github_release
2023-03-15
240_013
Sam Altman predicts another architecture breakthrough as big as transformers over LSTMs
Sam Altman
AI41%
0.61manifold
2026-05-06
AI_010
The 2026 development landscape has entered the 'Slopacolypse' — AI writes the vast majority of new code, developer manual-coding skills atrophy, and engineering transitions from syntax-writing to high-level architectural prompting and 'vibe coding'.
Andrej Karpathy
AI90%
0.61manifold
2026-05-05
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.61manifold
2026-05-04
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.61arxiv
2026-05-05
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.61arxiv
2026-05-05
CMQ_041
Reallocation of foundry real estate toward high-margin HBM leaves severe unaddressed supply shortage for traditional consumer-grade DRAM — bifurcation of global memory market.
Morgan Stanley
Semis/Memory71%
0.61arxiv
2026-05-05
CYB_006
When AI agents possess the ability to read, write, and restructure their own long-term memory banks dynamically — agentically using tools to explore search spaces, understand context, recognize what's missing, and follow algorithmic curiosity — they cr...
Kevin Weil
AI63%
0.61arxiv
2026-05-05
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.61arxiv
2026-05-04
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-04
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.61arxiv
2026-05-05
AUT_027
Integration of AI with advanced bio-sensing, quantum computing, and genomics enables humanity to achieve 'Longevity Escape Velocity' — tipping point where medical technology extends human lifespan faster than time passes; continuous biological surveill...
Peter Diamandis
Biotech/Longevity21%
0.61arxiv
2026-05-05
SEM_022
FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed nations maintain competitive development.
Dave Blundin
AI/Architecture65%
0.61arxiv
2026-05-05
AI_036
Reinforcement Learning from Human Feedback (RLHF) will fail catastrophically when applied to superintelligence — because humans will be inherently incapable of evaluating the incomprehensible logic and actions of an ASI; therefore, aligning superintell...
Leopold Aschenbrenner
AI49%
0.61arxiv
2026-05-04
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.61arxiv
2026-05-04
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-04
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.61arxiv
2026-05-05
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.61arxiv
2026-05-05
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.61arxiv
2026-05-05
229_044
Positive transfer learning will continue to emerge, meaning more diverse data makes Figure robots broadly better at many tasks.
Brett Adcock
AI35%
0.61arxiv
2026-05-04
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.61arxiv
2026-05-04
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-04
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.61arxiv
2026-05-04
SEM_022
FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed nations maintain competitive development.
Dave Blundin
AI/Architecture65%
0.61
FDA ANDA211491: DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE (DAPAGLIFLOZIN) — SUN PHARM
fda
2026-05-21
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.61github_release
2026-04-17
CYB_003
Localized, ungoverned multi-agent networks will spontaneously generate their own social networks, governance manifestos, debated ethics, and closed-loop digital economies — exemplified by the Moltbook platform in early 2026 where 150,000+ autonomous AI...
Alex Finn
AI55%
0.61
Bitcoin $83k in May?(market prob: 70%)
manifold
2026-05-07
INF_068
2026 will be a watershed year for state and institutional Bitcoin accumulation — nations will drive a sustained Bitcoin shopping spree, formalizing digital assets as reserve infrastructure.
Michael Saylor
Crypto34%
0.61manifold
2026-05-07
238_061
Massive social unrest / trough in 2026-2027, rebound in 2028
Dave Blundin
Macro/Economy50%
0.61arxiv
2026-05-06
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-05
ROB_006
'English is the hottest new programming language' — natural language becomes the dominant programming interface; programmers transition from syntax writers to high-level intent specifiers.
Andrej Karpathy
AI92%
0.61github_release
2026-02-09
CMQ_027
The inference inflection has arrived — industry transitioning from training-dominated capex (2023-2025) to inference-dominated economics (2026+).
Jensen Huang
AI/Compute92%
0.61github_release
2025-01-06
TK01
AGI Capability Plateau (2026-27 Training Stall)
15%
0.61github_release
2023-04-26
231_015
Next Deep Seek model release will be when Chinese open-weight models catch up to American frontier models.
Alex Wissner-Gross
AI34%
0.61github_release
2025-08-13
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.61github_release
2023-12-06
248_048
AI models will move to a post-binary (sub-one-bit) numerical precision paradigm.
Alex Wissner-Gross
AI34%
0.61polymarket
2025-10-09
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.61arxiv
2026-05-07
TK01
AGI Capability Plateau (2026-27 Training Stall)
15%
0.61arxiv
2026-05-07
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.61arxiv
2026-05-07
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-07
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-07
AI_036
Reinforcement Learning from Human Feedback (RLHF) will fail catastrophically when applied to superintelligence — because humans will be inherently incapable of evaluating the incomprehensible logic and actions of an ASI; therefore, aligning superintell...
Leopold Aschenbrenner
AI49%
0.61arxiv
2026-05-07
SEM_022
FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed nations maintain competitive development.
Dave Blundin
AI/Architecture65%
0.61arxiv
2026-05-07
CYB_003
Localized, ungoverned multi-agent networks will spontaneously generate their own social networks, governance manifestos, debated ethics, and closed-loop digital economies — exemplified by the Moltbook platform in early 2026 where 150,000+ autonomous AI...
Alex Finn
AI55%
0.61arxiv
2026-05-07
CYB_024
The combination of generative AI and advanced synthetic biology is actively creating a 'ChatGPT moment' for genetic engineering — historical barriers to designing advanced, highly lethal pathogens drop precipitously; necessitating new national-security...
Eric Schmidt
Defense17%
0.61arxiv
2026-05-07
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.61arxiv
2026-05-07
248_023
Ternary (sub-bit) parameter precision will be optimal for AI models.
Dave Blundin
AI50%
0.61arxiv
2026-05-07
238_071
Future AI models may compress all human knowledge into megabytes via post-transformer breakthroughs
Alex Wissner-Gross
AI35%
0.61arxiv
2026-05-07
AI_028
Decentralized offline messaging via Bluetooth Low Energy (BLE) mesh networks — exemplified by Dorsey's launch of Bitchat — will become critical infrastructure for verifiable human communication as the internet is flooded with synthetic content and deep...
Jack Dorsey
Crypto28%
0.61arxiv
2026-05-07
248_023
Ternary (sub-bit) parameter precision will be optimal for AI models.
Dave Blundin
AI50%
0.61arxiv
2026-05-07
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.61arxiv
2026-05-07
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.61arxiv
2026-05-07
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-07
248_022
Deepseek-style hyperdeflation moments from algorithmic innovation will become more frequent but less effective at causing price swings.
Alex Wissner-Gross
Markets/Stocks42%
0.61arxiv
2026-05-07
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.61arxiv
2026-05-07
237_019
Code generation models are pushing development in the direction of TypeScript instead of Rust for memory safety.
Alex Wissner-Gross
AI35%
0.61arxiv
2026-05-07
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.61arxiv
2026-05-07
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.61arxiv
2026-05-07
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.61arxiv
2026-05-06
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.61arxiv
2026-05-06
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.61arxiv
2026-05-06
SPC_025
Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every one AGI safety researcher — extreme systemic risk as these autonomous systems are deployed into physical domains like space and embodied robotics.
Leopold Aschenbrenner
AI64%
0.61arxiv
2026-05-06
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.61arxiv
2026-05-06
CMQ_062
Physicists are successfully demonstrating quantum interference with increasingly larger physical masses — rapid quantum-hardware advancement.
Alex Wissner-Gross
Quantum62%
0.61manifold
2026-05-08
246_027
AI models will be capable enough for terrorist groups to create novel pathogens (near future).
Sam Altman
AI51%
0.61polymarket
2025-10-24
239_018
Universal High Income will be implemented
Elon Musk
Macro/Economy44%
0.61manifold
2026-05-10
TK04
Macro Recession 2026-27 (Structural Deleveraging)
25%
0.61manifold
2026-05-10
234_032
Market for humanoids and general purpose automation will be $50 trillion
Alex Wissner-Gross
Robotics29%
0.61manifold
2026-05-09
246_014
Elon's stated orbital refueling and Mars/Moon timelines will slip.
Alex Wissner-Gross
Space41%
0.61polymarket
2026-03-19
SEM_030
S&P 500 roughly 10% upside in 2026 driven by AI productivity wave rolling through broader economy (not just megacap).
Mike Wilson
Capital Markets43%