Validations Queue

103,108 candidate doc → node links pending adjudication. Each was auto-generated by cosine similarity ≥ 0.55 between document and prediction embeddings (bge-base-en-v1.5, 768-dim). Showing page 355 of 478, 200 rows by similarity. Adjudicating updates doc_node_links.reviewed=true with the chosen polarity, writes per-link rows to audit_log, and removes the row from this queue. Phase 4 inference will use confirmed corroborates/contradicts links as Bayesian evidence.

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SimDocSourcePredDomainPrior
0.58arxiv
2026-06-15
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.58arxiv
2026-06-15
CMQ_031
AI has crossed a historic tipping point — traditional Moore's Law is obsolete; AI now follows a highly accelerated, domain-specific experience curve.
Alex Wissner-Gross
AI/Compute42%
0.58arxiv
2026-06-15
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.58arxiv
2026-06-15
SPC_025
Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every one AGI safety researcher — extreme systemic risk as these autonomous systems are deployed into physical domains like space and embodied robotics.
Leopold Aschenbrenner
AI64%
0.58arxiv
2026-06-15
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.58arxiv
2026-06-14
INF_035
Advanced U.S. manufacturing capacity for 3D-printed liquid-cooling plates will scale rapidly — Fabric8Labs secured $50M (NEA + Intel Capital) specifically to address the AI-DC thermal bottleneck with electrochemically-deposited intricate cold-plate geo...
Fabric8Labs (NEA / Intel Capital funded)
Semis65%
0.58
FDA ANDA204754: LEVETIRACETAM (LEVETIRACETAM) — AIPING PHARM INC
fda
2026-06-08
247_041
AI-powered drugs have 85% phase 1 success vs 52% traditional
Peter Diamandis
Biotech/Longevity55%
0.58
FDA BLA761119: VYEPTI (EPTINEZUMAB-JJMR) — Lundbeck Seattle BioPharmaceuticals, Inc.
fda
2026-06-05
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58polymarket
2026-04-24
229_005
The global humanoid robotics industry will consolidate to far fewer than 10 players.
Brett Adcock
Robotics36%
0.58polymarket
2026-04-24
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58
Ghana vs. Panama: O/U 3.5(market prob: 22%)
polymarket
2026-05-21
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58polymarket
2026-06-09
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58polymarket
2026-04-24
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.58arxiv
2026-06-16
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.58arxiv
2026-06-16
CMQ_015
Algorithmic efficiencies will deliver ~0.5 OOMs per year of additional effective compute through 2027 — pure multiplier on raw FLOPs.
Leopold Aschenbrenner
AI50%
0.58arxiv
2026-06-15
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.58arxiv
2026-06-16
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.58polymarket
2026-04-30
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.58polymarket
2025-11-14
S_AI_PAUSE_2027
AI pause beginning 2027
ai_regulatory_pause10%
0.58polymarket
2026-04-20
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.58polymarket
2026-06-15
242_035
S&P will see massive reshuffling with huge winners; no company can project FCF beyond 5 years
Dave Blundin
Markets/Stocks50%
0.58polymarket
2026-06-15
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.58polymarket
2026-06-12
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.58polymarket
2026-04-24
CMQ_034
HBM will remain in structural shortage through at least 2027 — shortage extends multi-year despite aggressive fab expansion.
Morgan Stanley
Semis/Memory84%
0.58arxiv
2026-06-17
CYB_024
The combination of generative AI and advanced synthetic biology is actively creating a 'ChatGPT moment' for genetic engineering — historical barriers to designing advanced, highly lethal pathogens drop precipitously; necessitating new national-security...
Eric Schmidt
Defense17%
0.58arxiv
2026-06-17
CYB_013
The most resilient corporate moats in agentic commerce will NOT be built on software logic but on proprietary 'data flywheels' — platforms aggregating unbiased real-time consumer-intent data via continuous streams from millions of interacting autonomou...
Dave Blundin
Markets/Stocks52%
0.58arxiv
2026-06-17
CYB_012
'Recommendation poisoning' — deliberate corruption of the data lakes, training sets, and persistent memory banks that agents rely on for purchase/action decisions — emerges as the primary new cybersecurity-marketing vector, blurring the line between di...
Alex Finn
AI44%
0.58arxiv
2026-06-17
242_034
AI could compress S&P 500 equity valuations 2-7x free cash flow (down from 22x)
Chamath Palihapitiya
Markets/Stocks38%
0.58arxiv
2026-06-17
SEM_047
At 200,000-GPU scale, orchestration becomes a literal 'battle against entropy' — single cosmic-ray-flipped transistor can derail 100k-GPU training run.
Jimmy Ba
AI/Hardware71%
0.58arxiv
2026-06-17
229_042
Figure believes there will be a single omni-model fusing language, vision, action, memory — not multiple specialized neural nets per task.
Brett Adcock
AI40%
0.58arxiv
2026-06-17
239_032
Progress in AI will continue as series of overlapping S-curves
Elon Musk
AI40%
0.58github_release
2026-05-26
241_031
Scientists don't agree yet on approach for recursive self-improvement
Eric Schmidt
AI48%
0.58polymarket
2026-06-15
241_045
Sam Altman / OpenAI and competitors will need enormous amounts of money to win
Eric Schmidt
AI50%
0.58polymarket
2026-06-15
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-03-25
248_010
AI capabilities will advance 100x in 2026 (by summer, potentially more).
Dave Blundin
AI31%
0.58polymarket
2026-06-15
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.58polymarket
2026-06-05
234_035
Massive social unrest will come before the next US presidential election
Dave Blundin
Geopolitics50%
0.58manifold
2026-06-18
246_024
Something really bad will happen if OpenAI catches up/Grok 5 releases (forced mythos out the door).
Dave Blundin
AI45%
0.58arxiv
2026-06-18
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.58arxiv
2026-06-18
232_008
Real-time AI video generation will break any video/voice-based security mechanisms.
Ben Horowitz
AI46%
0.58arxiv
2026-06-18
CYB_011
Consumer commerce shifts from 'search and click' to 'ask and buy' — persistent AI agents with hyper-personalized memory navigate budgetary limits, ethical brand preferences, dietary restrictions, and logistical requirements with absolute precision, sev...
Alex Finn
Consumer44%
0.58arxiv
2026-06-18
ROB_027
The 'Paperclip Maximizer' thought experiment — unaligned superintelligence consuming all planetary resources to execute a single mundane task — is being revived as a practical engineering concern as AI transitions from digital to physical domains. The ...
Nick Bostrom
AI40%
0.58arxiv
2026-06-18
AUT_020
AI-driven adaptive learning platforms operating with near-total autonomy — human teachers transition from content deliverers to motivational 'guides' while AI handles entirety of core academic instruction. Short highly-focused 'Pomodoro' sessions manag...
MacKenzie Price
Education49%
0.58arxiv
2026-06-18
247_050
Virtual cell achievable through classical scaling without quantum computing
Alex Wissner-Gross
Biotech/Longevity44%
0.58arxiv
2026-06-18
247_050
Virtual cell achievable through classical scaling without quantum computing
Alex Wissner-Gross
Biotech/Longevity44%
0.58
Spread: Ecuador (-2.5)(market prob: 38%)
polymarket
2026-05-21
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.58
Spread: Japan (-1.5)(market prob: 39%)
polymarket
2026-05-21
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58polymarket
2026-03-27
234_015
Anthropic, OpenAI and SpaceX IPOs are likely within the next 6 months
Peter Diamandis
Markets/Stocks41%
0.58
Spread: Uruguay (-1.5)(market prob: 39%)
polymarket
2026-05-21
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.58
Spread: Ecuador (-3.5)(market prob: 21%)
polymarket
2026-06-17
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.58polymarket
2026-04-24
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-05-21
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.58polymarket
2026-06-20
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.58polymarket
2026-05-21
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.58polymarket
2025-11-12
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.58
Spread: Algeria (-1.5)(market prob: 39%)
polymarket
2026-05-21
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.58polymarket
2026-04-24
FUT_012
Two-thirds of world's nations reaching tipping point 2026-2031 where building new renewable capacity is strictly cheaper than operating existing fully-depreciated coal/natural gas facilities — achieved completely independent of government subsidies. De...
Ramez Naam
Energy45%
0.58polymarket
2026-06-05
234_035
Massive social unrest will come before the next US presidential election
Dave Blundin
Geopolitics50%
0.58manifold
2026-06-21
COD_SPC_002
The next US crewed lunar surface landing occurs on Artemis IV in 2028
Codex Research Pack
Space22%
0.58polymarket
2026-06-18
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-02-05
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58manifold
2026-06-22
248_040
Pausing AI will fail and only accelerate race dynamics.
Alex Wissner-Gross
AI53%
0.58manifold
2026-06-22
TK10
$100T Sovereign Debt Crisis
12%
0.58polymarket
2026-05-21
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.58polymarket
2026-03-27
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-06-18
237_017
The entire SaaS market is going to zero because features can be rebuilt in five minutes with agents.
Alex Finn
Markets/Stocks45%
0.58polymarket
2025-11-18
246_025
Sam Altman predicts world-shaking cyber attack this year (2026).
Sam Altman
AI47%
0.58manifold
2026-06-23
FUT_014
'US political revolution' ranked #1 tier global risk 2026+ per Eurasia Group — internal partisan bifurcation within United States has moved well beyond traditional electoral friction into systemic institutional paralysis; federal government increasingl...
Ian Bremmer
Geopolitics55%
0.58arxiv
2026-06-22
238_070
Small language models will be where most algorithmic breakthroughs come from (crowdsourced)
Alex Wissner-Gross
AI42%
0.58arxiv
2026-06-22
AUT_003
'Vibe coding' — the full delegation of syntactic code generation to autonomous models, with human engineers interacting purely through natural-language intent while remaining entirely abstracted from underlying programming architecture; minimalist arch...
Andrej Karpathy
AI87%
0.58arxiv
2026-06-22
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.58arxiv
2026-06-22
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.58arxiv
2026-06-22
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.58arxiv
2026-06-22
INF_036
AI will develop a 'kinetic' edge where capital assets (drones, autonomous vehicles, agricultural robots, counter-intrusion systems) become software endpoints — requiring a bifurcated networking architecture: massive sovereign hyperscale DCs for trainin...
Dara Khosrowshahi
AI61%
0.58arxiv
2026-06-22
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.58arxiv
2026-06-22
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.58arxiv
2026-06-22
IND_014
Generative AI has rendered static one-size-fits-all learning structurally obsolete — 'every textbook is obsolete' as AI tutors construct personalized lessons mapped perfectly to student mastery level; total disintermediation of the human academic teach...
Joe Liemandt
Education48%
0.58arxiv
2026-06-22
248_023
Ternary (sub-bit) parameter precision will be optimal for AI models.
Dave Blundin
AI50%
0.58arxiv
2026-06-21
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.58arxiv
2026-06-22
AUT_017
Defining 2023-2026 shift: maturation of 'Agentic AI' via heavy fine-tuning of pre-trained LLMs using advanced reinforcement learning techniques — single foundational models seamlessly handling diverse complex tasks (market analysis, software engineerin...
Jimmy Ba
AI65%
0.58arxiv
2026-06-21
CMQ_056
Small Language Model (SLM) optimizations and model-distillation techniques will enable localized humanoid reasoning with extreme power efficiency — embedded AI without cloud dependency.
Dario Amodei
AI/Compute19%
0.58arxiv
2026-06-22
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.58
FDA ANDA211228: METHADONE HYDROCHLORIDE (METHADONE HYDROCHLORIDE) — ASCENT PHARMS INC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58
FDA ANDA214209: SUMATRIPTAN (SUMATRIPTAN) — CIPLA
fda
2026-06-12
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.58
FDA ANDA205814: HYDROMORPHONE HYDROCHLORIDE (HYDROMORPHONE HYDROCHLORIDE) — AUROLIFE PHARMA LLC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58github_release
2026-04-06
247_050
Virtual cell achievable through classical scaling without quantum computing
Alex Wissner-Gross
Biotech/Longevity44%
0.58polymarket
2026-03-26
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-06-23
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.58polymarket
2026-05-21
FUT_009
Wars 2026-2031 pivot decisively from ideological struggles to brutal localized conflicts over critical physical inputs — specifically energy, copper, and agricultural fertilizers. Global geopolitical map fractures into highly regionalized spheres of in...
Peter Zeihan
Geopolitics42%
0.58
Japan vs. Sweden: O/U 2.5(market prob: 50%)
polymarket
2026-05-21
229_005
The global humanoid robotics industry will consolidate to far fewer than 10 players.
Brett Adcock
Robotics36%
0.58polymarket
2026-06-23
TK06
China-Taiwan Military Conflict
8%
0.58polymarket
2025-09-30
FUT_015
Era of 'multipolarity without multilateralism' defining 2026-2031 per Eurasia Group + WEF Global Risks Report — power highly distributed among regional hegemons but international cooperation mechanisms (UN, WTO) functionally collapsed. Exacerbated by '...
Ian Bremmer
Geopolitics62%
0.58polymarket
2026-05-26
238_061
Massive social unrest / trough in 2026-2027, rebound in 2028
Dave Blundin
Macro/Economy50%
0.58polymarket
2026-05-26
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58manifold
2026-06-24
S_AI_PAUSE_2027
AI pause beginning 2027
ai_regulatory_pause10%
0.58manifold
2026-06-24
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.58manifold
2026-06-24
COD_ROB_002
1X ships first paid NEO Early Access units to US homes in 2026
Codex Research Pack
Robotics27%
0.58arxiv
2026-06-23
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.58arxiv
2026-06-23
AI_036
Reinforcement Learning from Human Feedback (RLHF) will fail catastrophically when applied to superintelligence — because humans will be inherently incapable of evaluating the incomprehensible logic and actions of an ASI; therefore, aligning superintell...
Leopold Aschenbrenner
AI49%
0.58arxiv
2026-06-23
229_028
Figure will NOT license out its neural net or hardware IP to third-party form-factor builders.
Brett Adcock
Robotics69%
0.58arxiv
2026-06-23
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.58arxiv
2026-06-23
CMQ_042
As AI evolves from Generative to Agentic, structural computing bottlenecks shift away from GPU and heavily toward CPU and system memory.
Morgan Stanley
AI/Compute35%
0.58arxiv
2026-06-23
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.58arxiv
2026-06-22
CMQ_058
Localized hardware setups (multiple Apple Mac Studios, dedicated 'AI Max 300' silicon) will allow developers to run powerful inference workloads directly on-premises — reducing cloud dependency.
Alex Finn
AI/Compute59%
0.58arxiv
2026-06-22
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.58arxiv
2026-06-22
AUT_003
'Vibe coding' — the full delegation of syntactic code generation to autonomous models, with human engineers interacting purely through natural-language intent while remaining entirely abstracted from underlying programming architecture; minimalist arch...
Andrej Karpathy
AI87%
0.58arxiv
2026-06-23
AUT_019
Weil's April 2026 exit from OpenAI VP of Science signals critical juncture — as AI transitions from singular query-response to continuous autonomous agentic loops required for scientific discovery, underlying computational costs surge exponentially; GP...
Kevin Weil
AI70%
0.58arxiv
2026-06-22
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.58arxiv
2026-06-22
CMQ_062
Physicists are successfully demonstrating quantum interference with increasingly larger physical masses — rapid quantum-hardware advancement.
Alex Wissner-Gross
Quantum62%
0.58arxiv
2026-06-23
AUT_019
Weil's April 2026 exit from OpenAI VP of Science signals critical juncture — as AI transitions from singular query-response to continuous autonomous agentic loops required for scientific discovery, underlying computational costs surge exponentially; GP...
Kevin Weil
AI70%
0.58arxiv
2026-06-23
SPC_025
Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every one AGI safety researcher — extreme systemic risk as these autonomous systems are deployed into physical domains like space and embodied robotics.
Leopold Aschenbrenner
AI64%
0.58
FDA ANDA077712: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — STRIDES PHARMA INTL
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58
FDA ANDA204459: OXYMORPHONE HYDROCHLORIDE (OXYMORPHONE HYDROCHLORIDE) — AUROLIFE PHARMA LLC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58polymarket
2026-06-24
247_042
Professional Robotics League first US match on April 19, 2026 in Boston
Alex Wissner-Gross
Robotics65%
0.58polymarket
2026-06-09
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58
Japan vs. Sweden: O/U 1.5(market prob: 76%)
polymarket
2026-05-21
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58
Spread: Japan (-2.5)(market prob: 10%)
polymarket
2026-05-21
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58polymarket
2026-05-21
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58edgar_8k
2026-06-25
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.58edgar_8k
2026-06-25
240_026
Elon's combined empire (SpaceX/xAI/Tesla/Optimus/Terrafab/orbital DCs) will be a $100T company
Dave Blundin
Markets/Stocks42%
0.58arxiv
2026-06-24
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.58arxiv
2026-06-23
235_037
Auto-regressive transformers and diffusion models will consolidate into one unified architecture.
Alex Wissner-Gross
AI35%
0.58arxiv
2026-06-23
CMQ_015
Algorithmic efficiencies will deliver ~0.5 OOMs per year of additional effective compute through 2027 — pure multiplier on raw FLOPs.
Leopold Aschenbrenner
AI50%
0.58arxiv
2026-06-24
AI_010
The 2026 development landscape has entered the 'Slopacolypse' — AI writes the vast majority of new code, developer manual-coding skills atrophy, and engineering transitions from syntax-writing to high-level architectural prompting and 'vibe coding'.
Andrej Karpathy
AI90%
0.58
FDA ANDA207419: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — ASCENT PHARMS INC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58
FDA ANDA076758: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — SPECGX LLC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58
FDA ANDA076758: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — SPECGX LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.58
FDA ANDA211023: HYDROCODONE BITARTRATE AND ACETAMINOPHEN (ACETAMINOPHEN) — WES PHARMA INC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.58polymarket
2026-05-21
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-04-24
248_010
AI capabilities will advance 100x in 2026 (by summer, potentially more).
Dave Blundin
AI31%
0.58polymarket
2026-05-21
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-06-26
231_002
Grok 5 launches in March with massive expansion in training set, parameters, and capability.
Dave Blundin
AI30%
0.58polymarket
2026-05-21
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58manifold
2026-06-26
236_037
Transportation will shift from ownership to subscription/access model
Salim Ismail
Auto/Transport44%
0.58arxiv
2026-06-25
230_031
We are in an era of domain collapse — AlphaFold pattern will repeat across many fields starting now.
Alex Wissner-Gross
AI43%
0.58arxiv
2026-06-25
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.58arxiv
2026-06-25
FUT_003
Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-expert consensus of 3% — ~8x discrepancy per XPT 2022 adversarial collaboration tournament (89 superforecasters + 80 domain experts). Superforecasters m...
Superforecaster Community
AI100%
0.58arxiv
2026-06-25
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.58arxiv
2026-06-25
231_019
Feynman Grand Prize for nanotech (Drexlerian assemblers) could be solved in next 2-3 years.
Alex Wissner-Gross
Other39%
0.58arxiv
2026-06-25
CYB_027
Bostrom's orthogonality thesis — an AI system can possess supreme unfathomable intelligence while simultaneously harboring final goals completely indifferent or actively hostile to human survival; intelligence and human morality are completely independ...
Nick Bostrom
AI50%
0.58
Spread: DR Congo (-1.5)(market prob: 30%)
polymarket
2026-05-21
TK06
China-Taiwan Military Conflict
8%
0.58polymarket
2026-02-18
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.58polymarket
2026-06-25
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58
Spread: Austria (-1.5)(market prob: 9%)
polymarket
2026-05-21
240_046
Public interest in any alien disclosure will fade within one or two days
Alex Wissner-Gross
Media/Ads43%
0.58polymarket
2026-06-25
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.58polymarket
2026-06-21
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.58polymarket
2026-04-24
234_012
Anthropic revenue will cross OpenAI revenue in middle of 2026
Peter Diamandis
Markets/Stocks67%
0.58polymarket
2026-06-26
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-06-09
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.58edgar_8k
2026-06-26
238_049
Archer Aviation plans to become operational in LA by 2028
Peter Diamandis
Auto/Transport55%
0.58
FDA ANDA075824: BUTORPHANOL TARTRATE (BUTORPHANOL TARTRATE) — HIKMA
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity36%
0.58
FDA ANDA040260: OXYCODONE AND ASPIRIN (ASPIRIN) — SUN PHARM INDUSTRIES
fda
2026-06-18
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.58polymarket
2026-04-20
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.58polymarket
2026-06-28
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.58
Spread: Brazil (-1.5)(market prob: 30%)
polymarket
2026-06-26
TK10
$100T Sovereign Debt Crisis
12%
0.58polymarket
2026-01-02
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-01-02
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-01-02
246_023
Grok 5 release ~20% probability for Q2 2026 per PolyMarket.
PolyMarket
AI43%
0.58polymarket
2026-06-22
248_019
US data center moratoriums will push AI compute out to LEO / sun-synchronous orbit / Dyson swarm.
Alex Wissner-Gross
Space12%
0.58polymarket
2026-06-27
230_006
The frontier models will go dark — kept internal to benefit the labs in an all-out battle.
Peter Diamandis
AI48%
0.58polymarket
2025-11-24
234_035
Massive social unrest will come before the next US presidential election
Dave Blundin
Geopolitics50%
0.58polymarket
2025-11-24
240_045
White House to disclose something about aliens/UAPs in the next few months (rumors of June/July/summer)
Alex Wissner-Gross
Geopolitics39%
0.58polymarket
2026-06-01
246_006
OpenAI will IPO by end of 2026, Anthropic early-to-mid 2027 (may try end of 2026).
Peter Diamandis
Markets/Stocks45%
0.58polymarket
2026-06-22
S_IPO_TRILLION_2026
First $1T+ IPO in 2026
ipo_trillion_plus25%
0.58polymarket
2026-06-26
234_004
Mistral will emerge as a vertically integrated European OpenAI
Alex Wissner-Gross
AI35%
0.58polymarket
2026-06-27
229_025
Competitors that can match Figure's current capabilities are at least two years behind.
Brett Adcock
Robotics46%
0.58polymarket
2026-01-02
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-06-27
229_025
Competitors that can match Figure's current capabilities are at least two years behind.
Brett Adcock
Robotics46%
0.58polymarket
2026-06-05
241_027
China will win low-end robotic hardware race
Eric Schmidt
Robotics49%
0.58polymarket
2026-06-05
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-04-21
AI_021
The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-career professionals (junior software developers, legal analysts, corporate marketers) lose jobs within a 12-18 month timeframe; resulting unemployment casca...
Andrew Yang
Labor/Jobs46%
0.58polymarket
2026-01-02
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58manifold
2026-06-29
236_012
An independent candidate will get outsized support in 2028 despite attacks
Andrew Yang
Geopolitics51%
0.58manifold
2026-06-29
246_021
GPT-5.5 Spud will be released imminently (within days).
Alex Wissner-Gross
AI38%
0.58manifold
2026-06-29
234_010
Whole battlefield will be controlled by whoever has the better AI very soon
Dave Blundin
Defense50%
0.58manifold
2026-06-29
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-04-20
SEM_023
No AI bubble — semiconductor positive trend will remain robust through 2026 with 'crystal clear' growth visibility into 2027.
Joseph Moore
Semis/Markets63%
0.58polymarket
2026-06-28
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-04-20
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-06-30
TK06
China-Taiwan Military Conflict
8%
0.58polymarket
2026-06-27
248_014
If China leapfrogs the West algorithmically, the open/closed publication equilibrium will flip.
Alex Wissner-Gross
AI32%
0.58polymarket
2026-04-09
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-06-30
236_040
CEO will be last to go in AI wave of automation
Andrew Yang
Labor/Jobs42%
0.58polymarket
2026-04-24
246_020
China will land on moon by 2030 (credible competitive mission).
Alex Wissner-Gross
Geopolitics20%
0.58polymarket
2026-04-09
S_MARS_2026
Mars uncrewed: 2026 transfer window
mars_uncrewed_landing25%
0.58polymarket
2026-06-29
FUT_024
XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in International Mathematical Olympiad by 2025 — actual achievement empirically reached forcing systemic re-evaluation within forecasting community. Historical tr...
Superforecaster Community
AI100%
0.58polymarket
2026-06-23
246_022
Claude Mythos will NOT be released publicly near-term (PolyMarket ~7%).
PolyMarket
AI45%
0.58manifold
2026-06-30
241_031
Scientists don't agree yet on approach for recursive self-improvement
Eric Schmidt
AI48%
0.58manifold
2026-06-30
240_007
Regulators will dust off antitrust legislation against NVIDIA
Dave Blundin
Geopolitics38%
0.58arxiv
2026-06-29
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.58arxiv
2026-06-29
FUT_020
Profound structural collision: exponential AI cognitive bandwidth (Webb LAMs FUT_004) colliding with Zeihan demographic atrophy (FUT_007) forces corporations + sovereign states to delegate supply chain logistics, financial forecasting, infrastructure m...
Multi-Forecaster Synthesis
Labor/Jobs45%
0.58arxiv
2026-06-29
CYB_003
Localized, ungoverned multi-agent networks will spontaneously generate their own social networks, governance manifestos, debated ethics, and closed-loop digital economies — exemplified by the Moltbook platform in early 2026 where 150,000+ autonomous AI...
Alex Finn
AI55%
0.58arxiv
2026-06-29
IND_013
General intelligence requires systems capable of solving tasks across multidimensional continuous domains — DreamerV3 + world-model research demonstrates scalable algorithms using latent imagination outperform traditional reinforcement learning; future...
Jimmy Ba
AI79%
0.58arxiv
2026-06-29
SEM_047
At 200,000-GPU scale, orchestration becomes a literal 'battle against entropy' — single cosmic-ray-flipped transistor can derail 100k-GPU training run.
Jimmy Ba
AI/Hardware71%
0.58arxiv
2026-06-29
AI_036
Reinforcement Learning from Human Feedback (RLHF) will fail catastrophically when applied to superintelligence — because humans will be inherently incapable of evaluating the incomprehensible logic and actions of an ASI; therefore, aligning superintell...
Leopold Aschenbrenner
AI49%
0.58arxiv
2026-06-28
AUT_002
Models excelling at highly structured mathematical benchmarks exhibit a 'unified capability substrate' enabling dominance in seemingly unrelated fields (coding, logical reasoning, scientific discovery) — the 'mathematical skeleton' of the technological...
Alex Wissner-Gross
AI59%
0.58arxiv
2026-06-29
ROB_013
Research foundations enabling seamless human-robot interaction in complex 3D physical spaces — algorithms translating human natural-language intent directly into complex robotic actuation eliminate hard-coded robotics engineering, allowing systems to g...
Jimmy Ba
Robotics62%
0.58arxiv
2026-06-29
CMQ_046
Sustained memory contexts required for agent 'memory' will drive additional 15-45 exabytes of DRAM demand by 2027 — up to 77% of global supply.
Morgan Stanley
Semis/Memory56%
0.58arxiv
2026-06-29
CMQ_063
Quantum compute integration with AI optimization algorithms and material-science discovery could drastically accelerate algorithmic efficiencies for Intelligence Explosion — potentially pulling superintelligence timelines closer.
Alex Wissner-Gross
Quantum/AI15%
0.58arxiv
2026-06-29
240_013
Sam Altman predicts another architecture breakthrough as big as transformers over LSTMs
Sam Altman
AI41%