Disease/drought-resistant plants and animals market is currently hundreds of billions of dollars
Predictor: Ben Lamm · ep#245 "AI + Synthetic Biology: The Most Transformative Technology in Human History | Ben Lamm (Colossal)" · source
Prediction text
Disease/drought-resistant plants and animals market is currently hundreds of billions of dollars | it it's hundreds of billions today and that's and it's just not well tracked
Verbatim quote
it it's hundreds of billions today and that's and it's just not well tracked
Predictor: Ben Lamm
Calibration plot (stated vs observed)
Evidence about this node from Ben Lamm is multiplied by κ in /api/intake. Lower κ = less weight; floors at 0.10 (effectively silenced) and caps at 1.00 (full weight).
Reference class
This node isn't linked to a reference class. The Bayesian update applies without outside-view blending.
Probability over time
Milestone chain
- 2026-04-12overdueColossal's 'Lamm $5.4T invasive-species' narrative is repeatedly cited by analystsHow: 247 Wall St. and at least two follow-on tier-2 outlets (Bloomberg, Reuters, FT, WSJ) cite Lamm's $5.4T invasive-species framing in 2026.Source: deep_research_enrichedconf 60%
- 2026-06-01 → 2027-06-30pendingColossal-affiliated Tropic Biosciences reports disease-resistant crop deploymentHow: Tropic Biosciences (a Colossal investee) reports gene-edited Panama-disease-resistant banana planted at commercial scale, with hectarage figure published.Source: deep_research_enrichedconf 55%
- 2026-06-01 → 2027-06-30pendingIndustry analyst sizes the disease-resistant ag-biotech market explicitlyHow: A major analyst (e.g. McKinsey, BCG, Lux, Boston Consulting, Bain, Bloomberg NEF) or the USDA publishes a sizing report estimating the genetic-resistance plant+animal market at >=$100B globally.Source: llm_enrichedconf 45%
- 2026-06-01 → 2027-12-31pendingColossal Foundation EEHV mRNA vaccine expands to additional zoos/herdsHow: Colossal Foundation announces vaccination beyond the initial Cincinnati Zoo cohort, with a deployed-dose count.Source: deep_research_enrichedconf 55%
- 2027-01-01 → 2028-06-30pendingFirst publicly traded comp pure-play in disease-resistant biotech announces revenueHow: A publicly traded firm explicitly classified as gene-edited disease-resistance reports >=$100M annualized revenue.Source: llm_enrichedconf 35%
What if this resolves?
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Evidence chain
Raw metadata
{
"trf": 1,
"kappa": 0.6875,
"base_rate": null,
"predictor": "Ben Lamm",
"total_llr": -0.4054651081081644,
"grace_days": 7,
"bayesian_v2": true,
"prior_logit": -0.3908139963572008,
"bayes_factor": "1.2:1 against",
"blend_reason": "no reference_class linked",
"inside_prior": 0.4035213630188968,
"kappa_source": "predictor_table",
"n_milestones": 1,
"blend_applied": false,
"contributions": [
{
"llr": -0.4054651081081644,
"kind": "llm_pre_event",
"kappa": 0.4125,
"label": "Colossal's 'Lamm $5.4T invasive-species' narrative is repeatedly cited by analysts",
"weight": 0.4,
"strength": "weak",
"confidence": 0.6,
"source_url": "https://247wallst.com/investing/2026/04/12/colossals-ben-lamm-says-invasive-species-is-a-5-4-trillion-problem-heres-his-solution/",
"adjusted_llr": -0.1672543570946178,
"expected_date": "2026-04-12",
"measurement_criterion": "247 Wall St. and at least two follow-on tier-2 outlets (Bloomberg, Reuters, FT, WSJ) cite Lamm's $5.4T invasive-species framing in 2026."
}
],
"evidence_kind": "metadata_milestone_miss_sweep",
"inside_source": "history_v2",
"inside_weight": 0.3,
"outside_weight": 0.7,
"posterior_prob": 0.36399452315422753,
"posterior_logit": -0.5580683534518186,
"predictor_brier": 0.00427,
"inside_posterior": 0.36399452315422753,
"blended_posterior": 0.36399452315422753,
"reference_class_id": null,
"total_adjusted_llr": -0.1672543570946178,
"predictor_n_resolved": 3
}Network propagation neighbors
Top incoming (parents)
Edges that influence THIS node's belief
| Kind | Node | Their prob | P(c|s=T) | P(c|s=F) | Δ implied |
|---|---|---|---|---|---|
| prereq | 234_012 Anthropic revenue will cross OpenAI revenue in middle of 202 — Peter Diamandis | 67.1% | 0.450 | 0.050 | -0.048 |
| killer | TK03 AI Regulatory Moratorium (EU/US Capability Freeze) | 10.0% | 0.050 | 0.450 | +0.046 |
| killer | TK01 AGI Capability Plateau (2026-27 Training Stall) | 15.0% | 0.050 | 0.450 | +0.026 |
| prereq | SEM_042 2025 will be the definitive year that agentic systems finall — Kevin Weil | 73.8% | 0.450 | 0.050 | -0.023 |
| prereq | SEM_012 Nvidia quadrupled chip production output while only doubling — Jensen Huang | 75.0% | 0.450 | 0.050 | -0.017 |
Top outgoing (children)
Predictions THIS node influences
| Kind | Node | Their prob | P(c|s=T) | P(c|s=F) | Δ implied |
|---|---|---|---|---|---|
| prereq | 231_013 Math is cooked (will be solved), physics cooked, biology cha — Alex Wissner-Gross | 35.4% | 0.620 | 0.050 | -0.095 |
| prereq | 241_043 ASI will arrive within 2 years to 5 years to this next decad — Peter Diamandis | 35.9% | 0.650 | 0.050 | -0.089 |
| prereq | 235_030 Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 203 — Ray Kurzweil | 39.2% | 0.750 | 0.050 | -0.086 |
| prereq | CMQ_002 By 2028, AI systems will reach 'independent researcher' leve — Sam Altman | 31.4% | 0.550 | 0.050 | -0.081 |
| prereq | 232_055 We're exiting the industrial age permanently as recursive se — Peter Diamandis | 35.5% | 0.700 | 0.050 | -0.067 |
Ticker exposure
Beneficiaries (23)
Adverse (6)
Prerequisites (8)
| Type | Pred | Title | Domain | Lag |
|---|---|---|---|---|
| prereq | SEM_008 | Training runs costing $10 billion for a single model will commence sometime in 2025. | AI | — |
| prereq | 238_009 | Recursive self-improvement is already happening now (no longer three years out) | AI | — |
| prereq | 234_012 | Anthropic revenue will cross OpenAI revenue in middle of 2026 | Markets/Stocks | — |
| prereq | SEM_012 | Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cursor, Claude Code) across engineering. | AI/Manufacturing | — |
| prereq | SEM_042 | 2025 will be the definitive year that agentic systems finally hit the mainstream. | AI/Agents | — |
| killer | TK14 | Superbubble Pop (S&P 500 -40%, Moonshot Capital Evaporates) | — | — |
| killer | TK01 | AGI Capability Plateau (2026-27 Training Stall) | — | — |
| killer | TK03 | AI Regulatory Moratorium (EU/US Capability Freeze) | — | — |
Dependents (5)
| Type | Pred | Title | Domain | Lag |
|---|---|---|---|---|
| prereq | 235_030 | Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. | Biotech/Longevity | — |
| prereq | 232_055 | We're exiting the industrial age permanently as recursive self-improvement unfolds. | AI | — |
| prereq | 241_043 | ASI will arrive within 2 years to 5 years to this next decade | AI | — |
| prereq | 231_013 | Math is cooked (will be solved), physics cooked, biology char broiled. | AI | — |
| prereq | CMQ_002 | By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human intervention. | AI | — |
Linked documents (2)
| Sim | Source | Title | Market prob | Polarity | Reviewed | Published |
|---|---|---|---|---|---|---|
| 0.576 | polymarket | Confirmed case of Hantavirus in US by May 15? | 12% | mentions | pending | 2026-05-04 |
| 0.568 | polymarket | Ebola case in the US by June 30? | 23% | mentions | pending | 2026-05-15 |
Raw metadata
{
"nia": false,
"qty": "Hundreds of billions USD",
"url": "https://www.youtube.com/watch?v=Goa6c6Qz__I",
"mode": "FORECAST",
"role": "Guest-CEO",
"caveats": "Not well tracked",
"context": "it it's hundreds of billions today and that's and it's just not well tracked, right?",
"to_year": 2026,
"verbatim": "it it's hundreds of billions today and that's and it's just not well tracked",
"conv_cues": "hundreds of billions today",
"direction": "NUMERIC_TARGET",
"from_year": 2026,
"timeframe": "Current",
"conv_level": "MEDIUM",
"milestones": [
{
"kind": "llm_pre_event",
"label": "Colossal's 'Lamm $5.4T invasive-species' narrative is repeatedly cited by analysts",
"source": "deep_research_enriched",
"status": "overdue",
"weight": 0.4,
"ordinal": -6,
"source_id": null,
"confidence": 0.6,
"source_url": "https://247wallst.com/investing/2026/04/12/colossals-ben-lamm-says-invasive-species-is-a-5-4-trillion-problem-heres-his-solution/",
"expected_date": "2026-04-12",
"miss_emitted_at": "2026-05-02T22:07:21.384228+00:00",
"miss_emitted_by": "metadata_milestone_sweep",
"research_origin": "deep_research",
"measurement_criterion": "247 Wall St. and at least two follow-on tier-2 outlets (Bloomberg, Reuters, FT, WSJ) cite Lamm's $5.4T invasive-species framing in 2026."
},
{
"kind": "prereq",
"label": "Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cursor, Claude Code) a",
"status": "hit",
"weight": 0.5,
"ordinal": -5,
"source_id": "SEM_012",
"expected_date": "2026-04-29",
"observed_date": "2026-04-29"
},
{
"kind": "prereq",
"label": "Training runs costing $10 billion for a single model will commence sometime in 2025.",
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"expected_date": "2026-04-29",
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},
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"kind": "prereq",
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{
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"label": "Recursive self-improvement is already happening now (no longer three years out)",
"status": "hit",
"weight": 0.5,
"ordinal": -1,
"source_id": "238_009",
"expected_date": "2026-04-29",
"observed_date": "2026-04-29"
},
{
"kind": "event",
"label": "Disease/drought-resistant plants and animals market is currently hundreds of billions of dollars",
"status": "pending",
"weight": 1,
"ordinal": 0,
"source_id": "245_017",
"expected_date": "2026-06-19",
"observed_date": null
},
{
"kind": "llm_pre_event",
"label": "Colossal-affiliated Tropic Biosciences reports disease-resistant crop deployment",
"source": "deep_research_enriched",
"status": "pending",
"weight": 0.4,
"ordinal": 1,
"source_id": null,
"confidence": 0.55,
"source_url": "https://research.contrary.com/company/colossal-biosciences",
"expected_date": "2026-12-15",
"research_origin": "deep_research",
"expected_date_range": {
"to": "2027-06-30",
"from": "2026-06-01"
},
"measurement_criterion": "Tropic Biosciences (a Colossal investee) reports gene-edited Panama-disease-resistant banana planted at commercial scale, with hectarage figur
... (truncated)