Mosquito gene drive halted in Africa was possibly wrong to stop since mosquitoes are part of the food web (but invasives are not)
Predictor: Ben Lamm · ep#245 "AI + Synthetic Biology: The Most Transformative Technology in Human History | Ben Lamm (Colossal)" · source
Prediction text
Mosquito gene drive halted in Africa was possibly wrong to stop since mosquitoes are part of the food web (but invasives are not) | people released gene drives in Africa around uh mosquitoes and everyone freaked out and then they stopped it... mosquitoes are a part of the food web. I don't think it was necessarily a bad idea to stop it because they were part of the food web, but we know invasive species are not a part of the food web
Watch events: ARC-AGI-2 scores; Frontier Math Tier 4 benchmark; SWE-bench Verified; Humanity's Last Exam
Verbatim quote
people released gene drives in Africa around uh mosquitoes and everyone freaked out and then they stopped it... mosquitoes are a part of the food web. I don't think it was necessarily a bad idea to stop it because they were part of the food web, but we know invasive species are not a part of the food web
Predictor: Ben Lamm
Calibration plot (stated vs observed)
Evidence about this node from Ben Lamm is multiplied by κ in /api/intake. Lower κ = less weight; floors at 0.10 (effectively silenced) and caps at 1.00 (full weight).
Reference class
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Probability over time
Milestone chain
- 2025-08-22hitBurkina Faso suspends Target Malaria gene-drive trial (Aug 2025)How: Burkina Faso government announces formal halt of Target Malaria gene-drive trialSource: deep_research_enrichedconf 98%
- 2025-12-01hitTanzania-based gene-drive Anopheles trial publishes peer-reviewed efficacyHow: Nature/Science peer-reviewed publication documenting gene-drive Anopheles inhibiting Plasmodium falciparum from patient samplesSource: deep_research_enrichedconf 90%
- 2027-01-01 → 2029-12-31pendingSecond African nation re-permits gene-drive Anopheles trialHow: Government of Uganda, Tanzania, or another African state issues regulatory authorization for an open-field gene-drive Anopheles releaseSource: llm_enrichedconf 50%
- 2028-09-09pendingQ1 window check-in (25%)
- 2027-01-01 → 2031-12-31pendingFirst gene-drive eradication targeting an invasive species achieves measurable population suppressionHow: Peer-reviewed paper or government report documents >=50% reduction in target invasive population in a defined geography via gene driveSource: llm_enrichedconf 40%
- 2028-01-01 → 2032-12-31pendingWHO/CBD adopts standardized gene-drive containment protocol distinguishing native vs invasiveHow: WHO Vector Control Advisory Group or Convention on Biological Diversity publishes formal guidance differentiating gene-drive use cases by ecological roleSource: llm_enrichedconf 40%
- 2031-01-21pendingQ2 window check-in (50%)
- 2033-06-02pendingQ3 window check-in (75%)
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Evidence chain
Network propagation neighbors
Top incoming (parents)
Edges that influence THIS node's belief
| Kind | Node | Their prob | P(c|s=T) | P(c|s=F) | Δ implied |
|---|---|---|---|---|---|
| prereq | S_ASI_SLOW_2040PLUS ASI slow: post-2040 / soft takeoff | 60.0% | 0.450 | 0.050 | -0.085 |
| killer | TK03 AI Regulatory Moratorium (EU/US Capability Freeze) | 10.0% | 0.050 | 0.450 | +0.035 |
| killer | TK01 AGI Capability Plateau (2026-27 Training Stall) | 15.0% | 0.050 | 0.450 | +0.015 |
Top outgoing (children)
Predictions THIS node influences
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Ticker exposure
Beneficiaries (21)
Adverse (7)
Prerequisites (3)
| Type | Pred | Title | Domain | Lag |
|---|---|---|---|---|
| prereq | S_ASI_SLOW_2040PLUS | ASI slow: post-2040 / soft takeoff | asi_recursive_self_improvement | — |
| killer | TK01 | AGI Capability Plateau (2026-27 Training Stall) | — | — |
| killer | TK03 | AI Regulatory Moratorium (EU/US Capability Freeze) | — | — |
Dependents (0)
| Type | Pred | Title | Domain | Lag |
|---|---|---|---|---|
| No dependents | ||||
Raw metadata
{
"nia": false,
"url": "https://www.youtube.com/watch?v=Goa6c6Qz__I",
"mode": "THESIS",
"role": "Guest-CEO",
"context": "people released gene drives in Africa around uh mosquitoes and everyone freaked out and then they stopped it... mosquitoes are a part of the food web. I don't think it was necessarily a bad idea to stop it because they were part of the food web, but we know invasive species are not a part of the food web",
"verbatim": "people released gene drives in Africa around uh mosquitoes and everyone freaked out and then they stopped it... mosquitoes are a part of the food web. I don't think it was necessarily a bad idea to stop it because they were part of the food web, but we know invasive species are not a part of the food web",
"conv_cues": "I don't think it was necessarily a bad idea",
"direction": "HAPPEN",
"timeframe": "Current",
"conv_level": "MEDIUM",
"milestones": [
{
"kind": "llm_pre_event",
"label": "Burkina Faso suspends Target Malaria gene-drive trial (Aug 2025)",
"source": "deep_research_enriched",
"status": "hit",
"weight": 0.4,
"ordinal": -8,
"source_id": null,
"confidence": 0.98,
"source_url": "https://countercurrents.org/2026/02/target-malaria-project-halted-in-burkina-faso-victory-for-opponents-of-open-field-gene-drive-releases/",
"expected_date": "2025-08-22",
"observed_date": "2025-08-22",
"research_origin": "deep_research",
"measurement_criterion": "Burkina Faso government announces formal halt of Target Malaria gene-drive trial"
},
{
"kind": "llm_pre_event",
"label": "Tanzania-based gene-drive Anopheles trial publishes peer-reviewed efficacy",
"source": "deep_research_enriched",
"status": "hit",
"weight": 0.4,
"ordinal": -7,
"source_id": null,
"confidence": 0.9,
"source_url": "https://www.nature.com/articles/s41586-025-09685-6",
"expected_date": "2026-02-14",
"observed_date": "2025-12-01",
"research_origin": "deep_research",
"expected_date_range": {
"to": "2026-06-30",
"from": "2025-10-01"
},
"measurement_criterion": "Nature/Science peer-reviewed publication documenting gene-drive Anopheles inhibiting Plasmodium falciparum from patient samples"
},
{
"kind": "llm_pre_event",
"label": "Second African nation re-permits gene-drive Anopheles trial",
"source": "llm_enriched",
"status": "pending",
"weight": 0.4,
"ordinal": -6,
"source_id": null,
"confidence": 0.5,
"expected_date": "2028-07-01",
"research_origin": "training",
"expected_date_range": {
"to": "2029-12-31",
"from": "2027-01-01"
},
"measurement_criterion": "Government of Uganda, Tanzania, or another African state issues regulatory authorization for an open-field gene-drive Anopheles release"
},
{
"kind": "quartile_checkpoint",
"label": "Q1 window check-in (25%)",
"status": "pending",
"weight": 0.05,
"ordinal": -5,
"source_id": null,
"expected_date": "2028-09-09",
"observed_date": null
},
{
"kind": "llm_pre_event",
"label": "First gene-drive eradication targeting an invasive species achieves measurable population suppression",
"source": "llm_enriched",
"status": "pending",
"weight": 0.4,
"ordinal": -4,
"source_id": null,
"confidence": 0.4,
"expected_date": "2029-07-01",
"research_origin": "training",
"expected_date_range": {
"to": "2031-12-31",
"from": "2027-01-01"
},
"measurement_criterion": "Peer-reviewed paper or government report documents >=50% reduction in target invasive population in a defined geography via gene drive"
},
{
"kind": "llm_post_event",
"label": "WHO/CBD adopts standardized gene-drive containment protocol distinguishing native vs inv
... (truncated)