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240_052predictionBiotech/LongevityAI-timing

Uploading consciousness (whole brain emulation) really will be you in the future

Predictor: Alex Wissner-Gross · ep#240 "NVIDIA's $1 Trillion Prediction, Anthropic Beats OpenAI, Tesla vs. TSMC & The CS Job Collapse" · source

Prior probability
45.0%
Current probability
40.6%
evolves via intake + LBP
Conviction
3/5
Signal quality
C
Resolution
pending
Window
— – —
Edges in / out
3 / 0
Tickers exposed
33

Prediction text

Uploading consciousness (whole brain emulation) really will be you in the future | I would say fully realized uploading is really going to be you. We're not there yet. It's not imminent

Watch events: Neuralink human trial enrollment; first commercial BCI

Verbatim quote

From episode "NVIDIA's $1 Trillion Prediction, Anthropic Beats OpenAI, Tesla vs. TSMC & The CS Job Collapse"
I would say fully realized uploading is really going to be you. We're not there yet. It's not imminent

Predictor: Alex Wissner-Gross

κ + Brier as of 2026-05-22
κ (discount)
0.844
Brier
0.0341
excellent
Hits / Misses
6 / 1
of 11 resolved
Hit rate
54.5%
Calibration plot (stated vs observed)

Evidence about this node from Alex Wissner-Gross is multiplied by κ in /api/intake. Lower κ = less weight; floors at 0.10 (effectively silenced) and caps at 1.00 (full weight).

Reference class

Not linked

This node isn't linked to a reference class. The Bayesian update applies without outside-view blending.

Probability over time

2 prob_history rows
0%25%50%75%100%prior 45%2026-04-302026-04-30
intake v2milestone miss sweeplbp propagationreference class assignedlegacy v1prior_prob (analyst seed)current = 40.6%

Milestone chain

Pre-event signals (upstream prereqs + window checkpoints) → resolution event → downstream cascades. Status/dates update from linked nodes; re-derive nightly via scripts/ops/derive_milestones.py.
Leading chain: 4 pending
  1. 2026-05-01 → 2026-12-31pendingCortical Labs CL1 maintains commercial neural compute platform with API access; whole-brain emulation NOT achieved
    How: CL1 platform remains commercially available with documented neuron lifetimes <12 months and minimal-viable-brain at <100 neurons (vs ~86B human neurons), per Cortical Labs roadmap and 2026 CL API paper
    Source: deep_research_enrichedconf 95%
  2. 2027-01-01 → 2030-12-31pendingConnectomics milestone: full mouse brain (~70M neurons) connectome mapped or in active mapping
    How: MICrONS / Allen Institute / Janelia announces completion or >50% progress on full-mouse-brain electron microscopy connectome, published in Nature or peer-reviewed venue
    Source: deep_research_enrichedconf 55%
  3. 2027-01-01 → 2030-12-31pendingPhilosophical surveys (PhilPapers / Bostrom Future of Humanity follow-ups) show no consensus on personal-identity continuity after WBE
    How: PhilPapers survey or equivalent of academic philosophers shows <60% agreement on the question 'a successful WBE upload is the same person as the original'
    Source: deep_research_enrichedconf 78%
  4. 2028-01-01 → 2032-12-31pendingWhole-brain emulation timelines pushed back: leading labs (Cortical, Allen Institute, OpenWorm follow-ups) project WBE >30 years out
    How: Cortical Labs / Allen / Future of Humanity Institute successor publishes roadmap citing >30 year WBE horizon, supporting 'not imminent' framing
    Source: deep_research_enrichedconf 62%

No downstream cascades — this prediction is a leaf in the dependency graph.

What if this resolves?

Clamp this prediction TRUE or FALSE and run a counterfactual Gibbs sample. Surfaces the predictions whose marginals shift most under that assumption.
(live posterior: 41%)

Click a button to clamp this prediction and run a Gibbs sample. Returns the predictions whose marginals shift most. ~30s per run; ideal for stress-testing "if X resolves, what else moves?"

Evidence chain

Every probability update with full Bayesian provenance — chronological, latest first
LBP2026-04-30T16:39:51Z40.6%-1.5pp
Network propagation: 42.1% → 40.6%
5-iter LBP, residual 0.00825 · damping 0.5, w_intrinsic 0.5 · method lbp_v2 · run 0c8a4ea3
LBP2026-04-30T02:18:57Z42.1%-2.9pp
Network propagation: 45.0% → 42.1%
5-iter LBP, residual 0.00825 · damping 0.5, w_intrinsic 0.5 · method lbp_v1 · run 592311ef

Network propagation neighbors

Top edges sorted by latest LBP cross-impact
All propagation →

Top incoming (parents)

Edges that influence THIS node's belief

KindNodeTheir probP(c|s=T)P(c|s=F)Δ implied
killerTK14
Superbubble Pop (S&P 500 -40%, Moonshot Capital Evaporates)
20.0%0.0500.450-0.036
killerTK01
AGI Capability Plateau (2026-27 Training Stall)
15.0%0.0500.450-0.016
killerTK03
AI Regulatory Moratorium (EU/US Capability Freeze)
10.0%0.0500.450+0.004

Top outgoing (children)

Predictions THIS node influences

No outgoing edges.

Ticker exposure

33 ticker(s) linked

Beneficiaries (23)

SOUNCRWVSITMNVDAARMGTLBBBAITSMAPLDCEVAAIMSFTMRVLSFTBYORCLQCOMAVGOBABAAMDGOOGLIBMAMZNMETA

Adverse (6)

WNSCHGGCTSHIBMINFYACN

Prerequisites (3)

Predictions that must hit first
TypePredTitleDomainLag
killerTK14Superbubble Pop (S&P 500 -40%, Moonshot Capital Evaporates)
killerTK01AGI Capability Plateau (2026-27 Training Stall)
killerTK03AI Regulatory Moratorium (EU/US Capability Freeze)

Dependents (0)

Predictions enabled by this
TypePredTitleDomainLag
No dependents

Linked documents (8)

Auto-generated by cosine similarity from Polymarket / Manifold / EDGAR / GDELT
SimSourceTitleMarket probPolarityReviewedPublished
0.696manifoldHumans have consciousness [Convince the Machine #3]98%mentionspending2026-05-03
0.643manifoldWill any nobel laureate donate their brain to https://bexorg.com/ by eoy2039?30%mentionspending2026-05-28
0.628manifoldAm I a brain in a vat?5%mentionspending2026-06-01
0.602manifoldAm I worthy of moral consideration [Convince the Machine #5]44%mentionspending2026-05-04
0.601manifoldWhen will Manifest 2026 upload videos of presentations to Youtube?mentionspending2026-06-03
0.600manifoldWhich of these will I achieve?mentionspending2026-04-24
0.573manifoldWill https://vivarium.sh/ still exist by EOY202824%mentionspending2026-05-07
0.550manifoldWill Eliezer Yudkowsky actually debate @47fucb4r8c69323?93%mentionspending2026-04-24

Raw metadata

From Thesis_Timeline_v1.0_FINAL workbook
{
  "nia": false,
  "url": "https://www.youtube.com/watch?v=uOGHXAfvK8w",
  "mode": "PREDICTION",
  "role": "Host",
  "caveats": "Missing science/biophysics; not imminent",
  "context": "I would say fully realized uploading is really going to be you. We're not there yet. It's not imminent, but in in a fully realized uploading technology stack...my expectation is it really will be you.",
  "verbatim": "I would say fully realized uploading is really going to be you. We're not there yet. It's not imminent",
  "conv_cues": "my expectation",
  "direction": "HAPPEN",
  "timeframe": "Future (not imminent)",
  "conv_level": "MEDIUM",
  "milestones": [
    {
      "kind": "llm_pre_event",
      "label": "Cortical Labs CL1 maintains commercial neural compute platform with API access; whole-brain emulation NOT achieved",
      "source": "deep_research_enriched",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -4,
      "source_id": null,
      "confidence": 0.95,
      "source_url": "https://corticallabs.com/cl1",
      "expected_date": "2026-08-31",
      "research_origin": "deep_research",
      "expected_date_range": {
        "to": "2026-12-31",
        "from": "2026-05-01"
      },
      "measurement_criterion": "CL1 platform remains commercially available with documented neuron lifetimes <12 months and minimal-viable-brain at <100 neurons (vs ~86B human neurons), per Cortical Labs roadmap and 2026 CL API paper"
    },
    {
      "kind": "llm_pre_event",
      "label": "Connectomics milestone: full mouse brain (~70M neurons) connectome mapped or in active mapping",
      "source": "deep_research_enriched",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -3,
      "source_id": null,
      "confidence": 0.55,
      "source_url": "https://www.microns-explorer.org/",
      "expected_date": "2028-12-31",
      "research_origin": "training",
      "expected_date_range": {
        "to": "2030-12-31",
        "from": "2027-01-01"
      },
      "measurement_criterion": "MICrONS / Allen Institute / Janelia announces completion or >50% progress on full-mouse-brain electron microscopy connectome, published in Nature or peer-reviewed venue"
    },
    {
      "kind": "llm_post_event",
      "label": "Philosophical surveys (PhilPapers / Bostrom Future of Humanity follow-ups) show no consensus on personal-identity continuity after WBE",
      "source": "deep_research_enriched",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -2,
      "source_id": null,
      "confidence": 0.78,
      "source_url": "https://philpapers.org/surveys/",
      "expected_date": "2028-12-31",
      "research_origin": "training",
      "expected_date_range": {
        "to": "2030-12-31",
        "from": "2027-01-01"
      },
      "measurement_criterion": "PhilPapers survey or equivalent of academic philosophers shows <60% agreement on the question 'a successful WBE upload is the same person as the original'"
    },
    {
      "kind": "llm_post_event",
      "label": "Whole-brain emulation timelines pushed back: leading labs (Cortical, Allen Institute, OpenWorm follow-ups) project WBE >30 years out",
      "source": "deep_research_enriched",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -1,
      "source_id": null,
      "confidence": 0.62,
      "source_url": "https://singularityhub.com/2025/12/11/how-scientists-are-growing-computers-from-human-brain-cells-and-why-they-want-to-keep-doing-it/",
      "expected_date": "2030-07-02",
      "research_origin": "deep_research",
      "expected_date_range": {
        "to": "2032-12-31",
        "from": "2028-01-01"
      },
      "measurement_criterion": "Cortical Labs / Allen / Future of Humanity Institute successor publishes roadmap citing >30 year WBE horizon, supporting 'not imminent' framing"
    }
  ],
  "repeat_eps": 1,
  "sub_domain": "Longevity",
  "untimeable": true,
  "affiliation": "Moonshots",
  "attribution": "FIRST_PERSON",
  "episode_num": 2
... (truncated)