Timeline Fan

88 of 88 tracked claims plotted by expected resolution date (X) × posterior probability (Y). Probabilities have already absorbed past + recent evidence (LBP + intake). Ghost arrows show how far each claim has moved off its analyst-seeded prior.

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0255075100historyPMCI_FSLR_20260511 resolved miss on 2026-05-18 — FSLR >10% in 5 trading days from 2026-05-11PMCI_FTNT_20260511 resolved miss on 2026-05-18 — FTNT >10% in 5 trading days from 2026-05-11PMCI_CDNS_20260511 resolved miss on 2026-05-18 — CDNS >10% in 5 trading days from 2026-05-11244_020 resolved partial on 2026-05-01 — Need for driver's licenses is going to collapse over the next few yearsPMCI_MKSI_20260518 resolved miss on 2026-05-25 — MKSI >10% in 5 trading days from 2026-05-18230_014 resolved hit on 2026-04-29 — The consulting industry will go through the roof as consultants leverage AI to automate/improve exisPMCI_ENVX_20260518 resolved hit on 2026-05-25 — ENVX >10% in 5 trading days from 2026-05-18PMCI_QCOM_20260515 resolved hit on 2026-05-22 — QCOM >10% in 5 trading days from 2026-05-15PMCI_MU_20260515 resolved miss on 2026-05-22 — MU >10% in 5 trading days from 2026-05-15PMCI_RRX_20260519 resolved hit on 2026-05-26 — RRX >10% in 5 trading days from 2026-05-19239_033 resolved partial on 2026-05-21 — Optimus 3 will be by far the most advanced robot in the worldINF_058 resolved partial on 2026-05-01 — The electrical grid topology will transition from centralized to highly decentralized: localized solPMCI_SNOW_20260505 resolved miss on 2026-05-12 — SNOW >10% in 5 trading days from 2026-05-05232_003 resolved partial on 2026-05-10 — AI will make workers 3x more productive, effectively reducing headcount by two-thirds unless compani238_010 resolved hit on 2026-04-29 — AI takeoff/inflection is happening now240_027 resolved hit on 2026-04-29 — SpaceX and xAI will merge and go public in the next couple of monthsAI_023 resolved hit on 2026-04-29 — Inside Uber, 90% of software engineers currently rely on AI, and executive teams rehearse high-stake236_033 resolved partial on 2026-05-17 — Pie will grow very quickly as AI does work of millions of humans in hours238_009 resolved hit on 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)CMQ_027 resolved hit on 2026-04-29 — The inference inflection has arrived — industry transitioning from training-dominated capex (2023-20AI_005 resolved hit on 2026-04-29 — Current frontier models suffer from 'jagged intelligence' — excelling at international mathematics o240_001 resolved hit on 2026-04-29 — NVIDIA to reach at least $1 trillion in bookings/revenue through 2027SEM_041 resolved partial on 2026-05-17 — At least 100,000 personal AI robots will be preordered in 2025 (driven by speech/vision/dexterity adAI_028 resolved partial on 2026-05-01 — Decentralized offline messaging via Bluetooth Low Energy (BLE) mesh networks — exemplified by DorseyFUT_024 resolved hit on 2026-04-29 — XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in InternaAUT_003 resolved hit on 2026-04-29 — 'Vibe coding' — the full delegation of syntactic code generation to autonomous models, with human en238_020 resolved partial on 2026-05-01 — Math field is 'cooked' — AI will solve research-level mathematics (first open hard math problem immi242_057 resolved hit on 2026-04-30 — Artemis 2 launches April 1, 2026 - circumlunar mission244_019 resolved hit on 2026-04-29 — Peter's son won't need a driver's license in 2 yearsPMCI_NVDA_20260505 resolved hit on 2026-05-12 — NVDA >10% in 5 trading days from 2026-05-05PMCI_TSLA_20260505 resolved hit on 2026-05-12 — TSLA >10% in 5 trading days from 2026-05-05PMCI_AGX_20260505 resolved miss on 2026-05-12 — AGX >10% in 5 trading days from 2026-05-05PMCI_ALAB_20260505 resolved miss on 2026-05-12 — ALAB >10% in 5 trading days from 2026-05-05PMCI_ASML_20260505 resolved hit on 2026-05-12 — ASML >10% in 5 trading days from 2026-05-05PMCI_CB_20260505 resolved miss on 2026-05-12 — CB >10% in 5 trading days from 2026-05-05PMCI_COHR_20260505 resolved hit on 2026-05-12 — COHR >10% in 5 trading days from 2026-05-05PMCI_CORZ_20260505 resolved hit on 2026-05-12 — CORZ >10% in 5 trading days from 2026-05-05PMCI_CRM_20260505 resolved miss on 2026-05-12 — CRM >10% in 5 trading days from 2026-05-05PMCI_CRWD_20260505 resolved hit on 2026-05-12 — CRWD >10% in 5 trading days from 2026-05-05PMCI_CRWV_20260505 resolved miss on 2026-05-12 — CRWV >10% in 5 trading days from 2026-05-05PMCI_GEV_20260505 resolved miss on 2026-05-12 — GEV >10% in 5 trading days from 2026-05-05231_002 resolved miss on 2026-04-29 — Grok 5 launches in March with massive expansion in training set, parameters, and capability.PMCI_FERG_20260505 resolved miss on 2026-05-12 — FERG >10% in 5 trading days from 2026-05-05PMCI_FIX_20260505 resolved miss on 2026-05-12 — FIX >10% in 5 trading days from 2026-05-05PMCI_GEHC_20260505 resolved miss on 2026-05-12 — GEHC >10% in 5 trading days from 2026-05-05PMCI_GFS_20260505 resolved miss on 2026-05-12 — GFS >10% in 5 trading days from 2026-05-05PMCI_LITE_20260505 resolved miss on 2026-05-12 — LITE >10% in 5 trading days from 2026-05-05PMCI_LMB_20260505 resolved miss on 2026-05-12 — LMB >10% in 5 trading days from 2026-05-05231_018 resolved miss on 2026-04-29 — Blitz will switch to next generation model in late March 2026.PMCI_LRCX_20260505 resolved miss on 2026-05-12 — LRCX >10% in 5 trading days from 2026-05-05PMCI_LUNR_20260505 resolved hit on 2026-05-12 — LUNR >10% in 5 trading days from 2026-05-05PMCI_MRVL_20260505 resolved miss on 2026-05-12 — MRVL >10% in 5 trading days from 2026-05-05PMCI_MSFT_20260505 resolved miss on 2026-05-12 — MSFT >10% in 5 trading days from 2026-05-05PMCI_MTSI_20260505 resolved hit on 2026-05-12 — MTSI >10% in 5 trading days from 2026-05-05PMCI_MU_20260505 resolved hit on 2026-05-12 — MU >10% in 5 trading days from 2026-05-05PMCI_NVO_20260505 resolved miss on 2026-05-12 — NVO >10% in 5 trading days from 2026-05-05PMCI_NXPI_20260505 resolved miss on 2026-05-12 — NXPI >10% in 5 trading days from 2026-05-05PMCI_OKLO_20260505 resolved hit on 2026-05-12 — OKLO >10% in 5 trading days from 2026-05-05PMCI_ORCL_20260505 resolved miss on 2026-05-12 — ORCL >10% in 5 trading days from 2026-05-05PMCI_RTX_20260505 resolved miss on 2026-05-12 — RTX >10% in 5 trading days from 2026-05-05PMCI_RUN_20260505 resolved miss on 2026-05-12 — RUN >10% in 5 trading days from 2026-05-05PMCI_PLTR_20260505 resolved miss on 2026-05-12 — PLTR >10% in 5 trading days from 2026-05-05PMCI_PYPL_20260505 resolved miss on 2026-05-12 — PYPL >10% in 5 trading days from 2026-05-05PMCI_QCOM_20260505 resolved hit on 2026-05-12 — QCOM >10% in 5 trading days from 2026-05-05PMCI_QLYS_20260505 resolved miss on 2026-05-12 — QLYS >10% in 5 trading days from 2026-05-05PMCI_RBRK_20260505 resolved miss on 2026-05-12 — RBRK >10% in 5 trading days from 2026-05-05PMCI_RIOT_20260505 resolved hit on 2026-05-12 — RIOT >10% in 5 trading days from 2026-05-05PMCI_RIVN_20260505 resolved miss on 2026-05-12 — RIVN >10% in 5 trading days from 2026-05-05PMCI_SAP_20260505 resolved miss on 2026-05-12 — SAP >10% in 5 trading days from 2026-05-05PMCI_TRU_20260505 resolved miss on 2026-05-12 — TRU >10% in 5 trading days from 2026-05-05PMCI_RKLB_20260505 resolved hit on 2026-05-12 — RKLB >10% in 5 trading days from 2026-05-05PMCI_RLAY_20260505 resolved miss on 2026-05-12 — RLAY >10% in 5 trading days from 2026-05-05PMCI_ROOT_20260505 resolved miss on 2026-05-12 — ROOT >10% in 5 trading days from 2026-05-05PMCI_TXN_20260505 resolved miss on 2026-05-12 — TXN >10% in 5 trading days from 2026-05-05PMCI_SYM_20260505 resolved miss on 2026-05-12 — SYM >10% in 5 trading days from 2026-05-05PMCI_T_20260505 resolved miss on 2026-05-12 — T >10% in 5 trading days from 2026-05-05PMCI_SERV_20260505 resolved miss on 2026-05-12 — SERV >10% in 5 trading days from 2026-05-05PMCI_TEM_20260505 resolved miss on 2026-05-12 — TEM >10% in 5 trading days from 2026-05-05PMCI_TSEM_20260505 resolved miss on 2026-05-12 — TSEM >10% in 5 trading days from 2026-05-05PMCI_TSM_20260505 resolved miss on 2026-05-12 — TSM >10% in 5 trading days from 2026-05-05PMCI_XIACY_20260505 resolved miss on 2026-05-12 — XIACY >10% in 5 trading days from 2026-05-05PMCI_VRT_20260505 resolved miss on 2026-05-12 — VRT >10% in 5 trading days from 2026-05-05PMCI_AAPL_20260505 resolved miss on 2026-05-12 — AAPL >10% in 5 trading days from 2026-05-05PMCI_TT_20260505 resolved miss on 2026-05-12 — TT >10% in 5 trading days from 2026-05-05PMCI_V_20260505 resolved miss on 2026-05-12 — V >10% in 5 trading days from 2026-05-05PMCI_XYL_20260505 resolved miss on 2026-05-12 — XYL >10% in 5 trading days from 2026-05-05PMCI_TMUS_20260505 resolved miss on 2026-05-12 — TMUS >10% in 5 trading days from 2026-05-05PMCI_SO_20260505 resolved miss on 2026-05-12 — SO >10% in 5 trading days from 2026-05-05PMCI_CIFR_20260505 resolved miss on 2026-05-12 — CIFR >10% in 5 trading days from 2026-05-05PMCI_SIEGY_20260505 resolved miss on 2026-05-12 — SIEGY >10% in 5 trading days from 2026-05-05PMCI_SPOT_20260505 resolved miss on 2026-05-12 — SPOT >10% in 5 trading days from 2026-05-05PMCI_SMMNY_20260505 resolved miss on 2026-05-12 — SMMNY >10% in 5 trading days from 2026-05-05PMCI_SBGSY_20260505 resolved miss on 2026-05-12 — SBGSY >10% in 5 trading days from 2026-05-05PMCI_XOM_20260505 resolved miss on 2026-05-12 — XOM >10% in 5 trading days from 2026-05-05PMCI_RYCEY_20260505 resolved miss on 2026-05-12 — RYCEY >10% in 5 trading days from 2026-05-05PMCI_VZ_20260505 resolved miss on 2026-05-12 — VZ >10% in 5 trading days from 2026-05-05PMCI_BRK.B_20260505 resolved miss on 2026-05-12 — BRK.B >10% in 5 trading days from 2026-05-05PMCI_BYDDY_20260505 resolved miss on 2026-05-12 — BYDDY >10% in 5 trading days from 2026-05-05PMCI_TM_20260505 resolved miss on 2026-05-12 — TM >10% in 5 trading days from 2026-05-05PMCI_UBER_20260505 resolved miss on 2026-05-12 — UBER >10% in 5 trading days from 2026-05-05PMCI_EADSY_20260505 resolved miss on 2026-05-12 — EADSY >10% in 5 trading days from 2026-05-05PMCI_WDAY_20260505 resolved miss on 2026-05-12 — WDAY >10% in 5 trading days from 2026-05-05241_004 resolved hit on 2026-04-29 — AI progress is not stoppable or controllable by any government, individual, or corporationPMCI_VST_20260505 resolved miss on 2026-05-12 — VST >10% in 5 trading days from 2026-05-05PMCI_SHOP_20260505 resolved miss on 2026-05-12 — SHOP >10% in 5 trading days from 2026-05-05PMCI_ABT_20260505 resolved miss on 2026-05-12 — ABT >10% in 5 trading days from 2026-05-05PMCI_ACLS_20260505 resolved hit on 2026-05-12 — ACLS >10% in 5 trading days from 2026-05-05PMCI_ACN_20260505 resolved miss on 2026-05-12 — ACN >10% in 5 trading days from 2026-05-05PMCI_MCHP_20260505 resolved miss on 2026-05-12 — MCHP >10% in 5 trading days from 2026-05-05PMCI_ADBE_20260505 resolved miss on 2026-05-12 — ADBE >10% in 5 trading days from 2026-05-05PMCI_ADI_20260505 resolved miss on 2026-05-12 — ADI >10% in 5 trading days from 2026-05-05PMCI_AEHR_20260505 resolved hit on 2026-05-12 — AEHR >10% in 5 trading days from 2026-05-05PMCI_ALL_20260505 resolved miss on 2026-05-12 — ALL >10% in 5 trading days from 2026-05-05PMCI_AMAT_20260505 resolved miss on 2026-05-12 — AMAT >10% in 5 trading days from 2026-05-05PMCI_AMT_20260505 resolved miss on 2026-05-12 — AMT >10% in 5 trading days from 2026-05-05PMCI_MDT_20260505 resolved miss on 2026-05-12 — MDT >10% in 5 trading days from 2026-05-05PMCI_MLI_20260505 resolved miss on 2026-05-12 — MLI >10% in 5 trading days from 2026-05-05PMCI_AMZN_20260505 resolved miss on 2026-05-12 — AMZN >10% in 5 trading days from 2026-05-05PMCI_ANET_20260505 resolved miss on 2026-05-12 — ANET >10% in 5 trading days from 2026-05-05PMCI_APLD_20260505 resolved hit on 2026-05-12 — APLD >10% in 5 trading days from 2026-05-05PMCI_ARM_20260505 resolved hit on 2026-05-12 — ARM >10% in 5 trading days from 2026-05-05PMCI_ASTS_20260505 resolved hit on 2026-05-12 — ASTS >10% in 5 trading days from 2026-05-05PMCI_AMD_20260505 resolved hit on 2026-05-12 — AMD >10% in 5 trading days from 2026-05-05PMCI_FRSH_20260505 resolved miss on 2026-05-12 — FRSH >10% in 5 trading days from 2026-05-05PMCI_INTC_20260505 resolved hit on 2026-05-12 — INTC >10% in 5 trading days from 2026-05-05PMCI_AVGO_20260505 resolved miss on 2026-05-12 — AVGO >10% in 5 trading days from 2026-05-05PMCI_AYI_20260505 resolved miss on 2026-05-12 — AYI >10% in 5 trading days from 2026-05-05PMCI_AZN_20260505 resolved miss on 2026-05-12 — AZN >10% in 5 trading days from 2026-05-05PMCI_BA_20260505 resolved miss on 2026-05-12 — BA >10% in 5 trading days from 2026-05-05PMCI_BE_20260505 resolved miss on 2026-05-12 — BE >10% in 5 trading days from 2026-05-05PMCI_BFLY_20260505 resolved miss on 2026-05-12 — BFLY >10% in 5 trading days from 2026-05-05PMCI_BTDR_20260505 resolved hit on 2026-05-12 — BTDR >10% in 5 trading days from 2026-05-05PMCI_BWXT_20260505 resolved miss on 2026-05-12 — BWXT >10% in 5 trading days from 2026-05-05PMCI_CAT_20260505 resolved miss on 2026-05-12 — CAT >10% in 5 trading days from 2026-05-05PMCI_CEG_20260505 resolved miss on 2026-05-12 — CEG >10% in 5 trading days from 2026-05-05PMCI_CHE_20260505 resolved miss on 2026-05-12 — CHE >10% in 5 trading days from 2026-05-05PMCI_CIEN_20260505 resolved miss on 2026-05-12 — CIEN >10% in 5 trading days from 2026-05-05PMCI_CINF_20260505 resolved miss on 2026-05-12 — CINF >10% in 5 trading days from 2026-05-05PMCI_CSCO_20260505 resolved miss on 2026-05-12 — CSCO >10% in 5 trading days from 2026-05-05PMCI_EME_20260505 resolved miss on 2026-05-12 — EME >10% in 5 trading days from 2026-05-05PMCI_EPAM_20260505 resolved miss on 2026-05-12 — EPAM >10% in 5 trading days from 2026-05-05PMCI_ETN_20260505 resolved miss on 2026-05-12 — ETN >10% in 5 trading days from 2026-05-05PMCI_F_20260505 resolved miss on 2026-05-12 — F >10% in 5 trading days from 2026-05-05PMCI_GLW_20260505 resolved hit on 2026-05-12 — GLW >10% in 5 trading days from 2026-05-05PMCI_GM_20260505 resolved miss on 2026-05-12 — GM >10% in 5 trading days from 2026-05-05PMCI_GOOGL_20260505 resolved miss on 2026-05-12 — GOOGL >10% in 5 trading days from 2026-05-05PMCI_HUT_20260505 resolved hit on 2026-05-12 — HUT >10% in 5 trading days from 2026-05-05PMCI_INFY_20260505 resolved miss on 2026-05-12 — INFY >10% in 5 trading days from 2026-05-05PMCI_IOT_20260505 resolved miss on 2026-05-12 — IOT >10% in 5 trading days from 2026-05-05PMCI_IREN_20260505 resolved hit on 2026-05-12 — IREN >10% in 5 trading days from 2026-05-05PMCI_LEU_20260505 resolved hit on 2026-05-12 — LEU >10% in 5 trading days from 2026-05-05PMCI_MA_20260505 resolved miss on 2026-05-12 — MA >10% in 5 trading days from 2026-05-05PMCI_META_20260505 resolved miss on 2026-05-12 — META >10% in 5 trading days from 2026-05-05PMCI_MRNA_20260505 resolved hit on 2026-05-12 — MRNA >10% in 5 trading days from 2026-05-05PMCI_NEE_20260505 resolved miss on 2026-05-12 — NEE >10% in 5 trading days from 2026-05-05PMCI_NET_20260505 resolved miss on 2026-05-12 — NET >10% in 5 trading days from 2026-05-05PMCI_NFLX_20260505 resolved miss on 2026-05-12 — NFLX >10% in 5 trading days from 2026-05-05PMCI_NOW_20260505 resolved miss on 2026-05-12 — NOW >10% in 5 trading days from 2026-05-05PMCI_ANET_20260506 resolved miss on 2026-05-13 — ANET >10% in 5 trading days from 2026-05-06PMCI_AMD_20260506 resolved miss on 2026-05-13 — AMD >10% in 5 trading days from 2026-05-06PMCI_ACN_20260506 resolved miss on 2026-05-13 — ACN >10% in 5 trading days from 2026-05-06PMCI_FIX_20260506 resolved miss on 2026-05-13 — FIX >10% in 5 trading days from 2026-05-06PMCI_CINF_20260507 resolved miss on 2026-05-14 — CINF >10% in 5 trading days from 2026-05-07PMCI_BFLY_20260507 resolved miss on 2026-05-14 — BFLY >10% in 5 trading days from 2026-05-07PMCI_BE_20260511 resolved miss on 2026-05-18 — BE >10% in 5 trading days from 2026-05-11PMCI_DVA_20260511 resolved miss on 2026-05-18 — DVA >10% in 5 trading days from 2026-05-11PMCI_KTOS_20260511 resolved miss on 2026-05-18 — KTOS >10% in 5 trading days from 2026-05-11PMCI_S_20260511 resolved miss on 2026-05-18 — S >10% in 5 trading days from 2026-05-11PMCI_BE_20260512 resolved miss on 2026-05-19 — BE >10% in 5 trading days from 2026-05-12PMCI_FORM_20260513 resolved miss on 2026-05-20 — FORM >10% in 5 trading days from 2026-05-13PMCI_AMKR_20260513 resolved miss on 2026-05-20 — AMKR >10% in 5 trading days from 2026-05-13PMCI_AMD_20260513 resolved miss on 2026-05-20 — AMD >10% in 5 trading days from 2026-05-13PMCI_QCOM_20260514 resolved miss on 2026-05-21 — QCOM >10% in 5 trading days from 2026-05-14PMCI_AMD_20260514 resolved miss on 2026-05-21 — AMD >10% in 5 trading days from 2026-05-14PMCI_ICHR_20260514 resolved miss on 2026-05-21 — ICHR >10% in 5 trading days from 2026-05-14PMCI_MU_20260514 resolved miss on 2026-05-21 — MU >10% in 5 trading days from 2026-05-14PMCI_CRWV_20260514 resolved miss on 2026-05-21 — CRWV >10% in 5 trading days from 2026-05-14PMCI_ETN_20260514 resolved miss on 2026-05-21 — ETN >10% in 5 trading days from 2026-05-14PMCI_CRWV_20260515 resolved miss on 2026-05-22 — CRWV >10% in 5 trading days from 2026-05-15PMCI_BE_20260515 resolved hit on 2026-05-22 — BE >10% in 5 trading days from 2026-05-15PMCI_LITE_20260518 resolved miss on 2026-05-25 — LITE >10% in 5 trading days from 2026-05-18PMCI_MU_20260518 resolved hit on 2026-05-25 — MU >10% in 5 trading days from 2026-05-18PMCI_BE_20260518 resolved hit on 2026-05-25 — BE >10% in 5 trading days from 2026-05-18PMCI_SLDP_20260518 resolved hit on 2026-05-25 — SLDP >10% in 5 trading days from 2026-05-18PMCI_QCOM_20260518 resolved hit on 2026-05-25 — QCOM >10% in 5 trading days from 2026-05-18PMCI_CB_20260601 resolved miss on 2026-06-08 — CB >10% in 5 trading days from 2026-06-01PMCI_RMBS_20260601 resolved hit on 2026-06-08 — RMBS >10% in 5 trading days from 2026-06-01PMCI_AMPX_20260601 resolved miss on 2026-06-08 — AMPX >10% in 5 trading days from 2026-06-01231_031 resolved partial on 2026-05-10 — OpenAI planning $100B infrastructure spend, going public this year at $1T valuation.229_047 resolved hit on 2026-04-29 — Figure's 3,000 B200 GPU cluster is coming online for Helix pre-training with much larger GPUs planneIND_021 resolved hit on 2026-04-29 — February 2026 realized forecast: AI automation capabilities necessitated severe operational restructCMQ_036 resolved partial on 2026-12-31 — SK Hynix will maintain industry HBM lead, capturing >50% of NVIDIA's total HBM procurement (HBM3E + SPC_008 resolved hit on 2026-04-29 — SpaceX milestone-delivery statistics: 16% on-time, 31% late, 53% undelivered overall — planetary milSEM_048 resolved hit on 2026-04-30 — OpenAI restructured into a $500 billion colossus by removing profit caps for investors (to support SSPC_025 resolved hit on 2026-04-29 — Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every on235_008 resolved miss on 2026-04-29 — Anthropic/OpenAI will be forced to release first-party OpenClaw competitor in next couple months.246_001 resolved partial on 2026-09-30 — SpaceX will IPO at $2 trillion valuation, raising $75 billion as largest IPO in history.AI_021 resolved partial on 2026-05-03 — The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-caree232_021 resolved hit on 2026-04-29 — No chance AI will be paused in the next three years given current administration and China competiti241_006 resolved hit on 2026-04-29 — Everyone is out of hardware and electricity due to AI boomAUT_019 resolved hit on 2026-04-29 — Weil's April 2026 exit from OpenAI VP of Science signals critical juncture — as AI transitions from 242_015 resolved hit on 2026-04-29 — Full autonomy achieved within 2 years before Salim's son gets driver's license234_012 resolved hit on 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026233_020 resolved hit on 2026-04-29 — Texas Sports Academy will operate at $300/month per parent using Texas billion-dollar voucher prograCMQ_043 resolved hit on 2026-04-29 — In complex Agentic AI workloads, CPU-side processing accounts for 50-90% of end-to-end latency — val246_008 resolved partial on 2026-05-01 — Elon Musk will merge SpaceX and XAI (with Tesla) within a year (Peter's view).246_038 resolved hit on 2026-04-29 — Data centers are driving frontier labs into space (orbital data centers).238_041 resolved hit on 2026-04-29 — Apple will eventually integrate highly competent private frontier models into its OS (when not if)247_023 resolved partial on 2026-05-17 — AI will be able to do everything a white collar worker does imminently247_042 resolved hit on 2026-04-29 — Professional Robotics League first US match on April 19, 2026 in BostonAUT_017 resolved hit on 2026-04-29 — Defining 2023-2026 shift: maturation of 'Agentic AI' via heavy fine-tuning of pre-trained LLMs using245_008 resolved partial on 2026-05-24 — More direwolves will be produced after initial Romulus and RemusIND_013 resolved hit on 2026-04-29 — General intelligence requires systems capable of solving tasks across multidimensional continuous doINF_005 resolved partial on 2026-05-01 — Skilled trade labor (welders, HVAC, electricians, plumbers, heavy-equipment operators, network technAI_016 resolved hit on 2026-04-29 — The 'cost of intelligence' collapse has officially superseded traditional Moore's Law dynamics — an CMQ_053 resolved hit on 2026-04-30 — Figure AI secured $675M Series B in 2024 and partnered commercially with BMW — addressing skilled-laINF_029 resolved partial on 2026-05-03 — Enterprise AI will shift the software economy from licensing to 'outcome-based economics' — corporat246_005 resolved partial on 2026-05-10 — OpenAI and Anthropic IPOs will head toward $1 trillion valuations.AI_010 resolved hit on 2026-04-29 — The 2026 development landscape has entered the 'Slopacolypse' — AI writes the vast majority of new cINF_036 resolved partial on 2026-05-01 — AI will develop a 'kinetic' edge where capital assets (drones, autonomous vehicles, agricultural robCYB_018 resolved hit on 2026-04-29 — Figure AI valuation has eclipsed $39 billion by early 2026 — surpassing SpaceX's 2020 valuation — baSEM_049 resolved partial on 2026-05-24 — AI will soon fully automate software engineering, achieving massive cost reductions via iterative se247_058 resolved hit on 2026-04-29 — Jury selection begins April 27, 2026 for Musk v OpenAI trial235_002 resolved hit on 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026).245_012 resolved hit on 2026-04-29 — UAE's Biovault is a nine-figure initiative for both Colossal and the UAE246_047 resolved hit on 2026-04-29 — Anthropic ARR reached $30B, surpassing OpenAI's $24-25B.CYB_026 resolved hit on 2026-04-29 — The initial assumption that the United States can maintain a durable long-term 'moat' based purely oFUT_003 resolved hit on 2026-04-29 — Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain-ROB_002 resolved partial on 2025-12-31 — 99% of code generation will be entirely automated by the end of 2025 — the elimination of the primarROB_006 resolved hit on 2026-04-29 — 'English is the hottest new programming language' — natural language becomes the dominant programminINF_004 resolved partial on 2026-05-17 — China has massive latent 'ghost data center' capacity — fully powered facilities sitting empty awaitROB_012 resolved hit on 2026-04-29 — The ultimate bottleneck for global robotics deployment is NOT software architecture but physical GPUINF_019 resolved hit on 2026-04-29 — A modern hyperscale AI data center can consume up to 5 million gallons of freshwater per day for evaINF_033 resolved hit on 2026-04-29 — Technology conglomerates have mobilized unprecedented political capital to ensure AI-friendly regulaSEM_033 resolved partial on 2026-05-10 — AI is gaining the capability to autonomously conduct original physics research (e.g., GPT-5.2 Pro prSEM_039 resolved hit on 2026-04-29 — Block unveiled proprietary Bitcoin mining ASIC at 709 Terahashes/second (TH/s) — leading indicator fSEM_042 resolved hit on 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.INF_039 resolved hit on 2026-04-29 — Consumer-facing AI hardware shortages will worsen: high-Unified-Memory Apple Mac Studio lead times nINF_060 resolved partial on 2026-05-10 — Three new battery chemistries beyond lithium-ion will commercialize in 2026 — signaling a definitive229_013 resolved hit on 2026-04-29 — The next 12-18 months will be the largest AI transformation ever seen.248_040 resolved hit on 2026-04-29 — Pausing AI will fail and only accelerate race dynamics.248_005 resolved hit on 2026-04-29 — V3 Starlink satellites will deliver over 1 TB/s downlink and 200+ Gbps uplink each.ROB_016 resolved hit on 2026-04-29 — Block executed massive layoffs explicitly reframing the company as a 'smaller, faster, intelligence-CMQ_038 resolved hit on 2026-12-31 — Micron has initiated HVM production of HBM4 36GB module delivering 2.8 TB/s bandwidth — optimized to235_038 resolved hit on 2026-04-29 — David Sinclair begins partial epigenetic reprogramming trials with Life Biosciences in March 2026.SEM_002 resolved partial on 2026-05-21 — By 2025-2026, AI model outputs will outpace the cognitive capabilities of college graduates (driven SEM_011 resolved hit on 2026-04-30 — Nvidia became the world's first $5 trillion company (late 2025), operating a near-monopoly on advancSEM_014 resolved hit on 2026-04-30 — Nvidia's Arizona-based TSMC factory successfully fabricated cutting-edge semiconductors on US soil fSEM_022 resolved partial on 2026-05-01 — FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed na237_028 resolved hit on 2026-04-29 — Abundance Summit will live-stream Eric Schmidt, Uber CEO Dara Khosrowshahi, and a WTF Moonshot podca238_072 resolved hit on 2026-04-29 — Small-to-large model scaling time has collapsed from 6-12 months to 6 daysSEM_021 resolved partial on 2026-05-10 — Largest AI models will see a 100x leap in size by 2026, driven largely by Chinese research efforts uSEM_037 resolved partial on 2026-05-17 — For any job you can do on the other side of a screen, AI will probably be able to do it better, fast232_014 resolved hit on 2026-04-29 — Recursive self-improvement is already here, not 12 months away.SEM_040 resolved partial on 2026-05-03 — Bitcoin treasury/business strategy allows companies to outpace rival enterprise software firms by 10241_052 resolved hit on 2026-04-29 — Standard AI data centers being built at 400 MW scale, half-mile longSEM_045 resolved partial on 2026-05-03 — Traditional corporate structures will move rapidly toward AI-native operating models by 2026 — forci245_025 resolved hit on 2026-04-29 — Colossal gene editing efficiency has risen from 15% industry / 40% internal to 90% at hundreds of edSPC_014 resolved hit on 2026-04-29 — Starlink constitutes 65% of all active satellites globally by 2026 — making LEO operational manageme248_003 resolved hit on 2026-04-29 — SpaceX plans to launch 40,000 V3 Starlink satellites and then 120,000 V4 satellites.SPC_031 resolved hit on 2026-04-29 — SpaceX's reusability program has driven the cost per kilogram to Low Earth Orbit from $15,600 in 200229_028 resolved hit on 2026-04-29 — Figure will NOT license out its neural net or hardware IP to third-party form-factor builders.CYB_015 resolved hit on 2026-04-29 — The human hiring process becomes progressively distorted as autonomous bot agents actively screen reCYB_003 resolved partial on 2026-05-17 — Localized, ungoverned multi-agent networks will spontaneously generate their own social networks, goCYB_009 resolved hit on 2026-04-29 — Hardware-software alignment will force widespread foundational-codebase rewrites — exemplified by MiCYB_029 resolved hit on 2026-04-29 — Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by AnthrSEM_029 resolved hit on 2026-04-29 — Blackwell RTX PRO 5000 (72GB) engineered with 50% memory boost over previous generation — deliberateINF_008 resolved partial on 2026-05-01 — Leading AI model intelligence has been improving by roughly 2.5 IQ points per month since May 2024 —INF_031 resolved partial on 2028-10-31 — The biggest near-term AI risk to humanity is AI companies themselves acting without proper oversightINF_030 resolved partial on 2026-05-01 — By 2026, generative AI will democratize analytical and operational capabilities previously exclusiveINF_049 resolved hit on 2026-04-29 — Modern AI data centers are no longer server farms but "gigawatt factories"; energy — not silicon supINF_065 resolved hit on 2026-04-29 — Uber has committed an initial $100 million specifically to develop EV charging infrastructure tailorSEM_006 resolved partial on 2025-12-31 — OpenAI will operate at a ~$9B deficit in 2025, driven almost entirely by advanced-chip acquisition aSEM_008 resolved hit on 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.SEM_012 resolved hit on 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deployingSEM_027 resolved hit on 2026-04-29 — Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap SPC_004 resolved hit on 2026-04-29 — Rocket Lab USA (RKLB) will leverage its dominance in the small-to-medium launch market — 2025 revenuSPC_006 resolved hit on 2026-04-29 — Starlink exceeded 10 million active global subscribers by February 2026, generating estimated annualJan 2026FebMarAprMayJunJulAugSepOctNovDecJan 2027FebMarAprMayJunJulAugSepOctNovDecJan 2028FebMarAprMayJunJulAugSepOctNovDecJan 2029FebMarAprMayJunJulAugSepOctNovDecJan 2030FebMarAprMayJunJulAugSepOctNovDecJan 2031FebMarAprMayJunJulAugSepOctNovDecJan 2032FebMarAprMayJunJulAugSepOctNovDecJan 2033FebMarAprMayJunJulAugSepOctNovDecJan 2034FebMarAprMayJunJulAugSepOctNovDecJan 2035FebMarAprMayJunJulAugSepOctNovDecJan 2036FebMarAprMayJunJulAugSepOctNovDecJan 2037FebMarAprMayJunJulAugSepOctNovDecJan 2038FebMarAprMayJunJulAugSepOctNovDecJan 2039FebMarAprMayJunJulAugSepOctNovDecJan 2040FebMarAprMayJunJulAugSepOctNovDecJan 2041FebMarAprMayJunJulAugSepOctNovDecJan 2042FebMarAprMayJunJulAugSepOctNovDecJan 2043FebMarAprMayJunJulAugSepOctNovDecJan 2044FebMarAprMayJunJulAugSepOctNovDecJan 2045FebMarAprMayJunJulAugSepOctNovDecJan 2046FebMarAprMayJuntodaypre #4 · partial · 2025-11-30 — At least 100,000 personal AI robots will be preordered in 2025 (driven by speech/vision/dexterity advances).pre #3 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #2 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #1 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.cascade #1 · pending · 2027-06-17 — Fast food chains will bring in humanoid robots very shortly to replace workers.cascade #2 · pending · 2027-09-03 — Amazon Zoox Robotaxi will launch in LA in 2027cascade #3 · pending · 2028-06-21 — Humanoid robots will be utterly transformative for 2/3 of US services sectorcascade #4 · pending · 2030-06-24 — Humanoid robot assembly of rockets is beyond current robots for a long timecascade #5 · pending · 2032-12-15 — Optimus/humanoid robots to do trades work in 3 to 8 years (Elon's vision)pre #6 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026).pre #5 · pending · 2027-09-16 — ATP-BIO consortium or NIH funds >=$50M dedicated organ-banking initiativepre #4 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump adpre #3 · pending · 2028-07-01 — Reversibly cryopreserved mammalian organ successfully transplanted into recipientpre #2 · pending · 2028-09-30 — 21st Century Medicine or competitor publishes large-mammal whole-brain reversible vitrificationpre #1 · pending · 2029-03-31 — FDA opens pre-IND track for vitrified-organ transplant trialcascade #1 · pending · 2032-07-01 — First UNOS-listed transplant using cryopreserved organcascade #2 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve ecascade #6 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026).pre #1 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.cascade #1 · pending · 2030-04-18 — Dario Amodei will solve most/all neurological diseases by end of decadecascade #2 · pending · 2030-10-10 — Europa Clipper will arrive at Jupiter in 2030, conducting 50 passes near Europa.cascade #3 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #4 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve epre #6 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #5 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026).pre #4 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump adpre #3 · pending · 2028-12-31 — AI healthcare reduces all-cause mortality in any large-scale deploymentpre #2 · pending · 2029-07-01 — AI sudden-cardiac-death detection deployed at population scalepre #1 · pending · 2031-10-01 — Global daily mortality decreases despite population growthcascade #1 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #2 · pending · 2036-08-14 — People will be on Mars within 10 yearscascade #3 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #4 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow.cascade #5 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040pre #6 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #5 · pending · 2026-06-25 — Nvidia agreed to remit 15% of China chip-sale revenue directly to US government in exchange for reversing specific AI chpre #4 · pending · 2027-05-02 — Neuralink human trial enrollment exceeds 50 participantspre #3 · pending · 2030-07-02 — FDA grants first non-medical / cognitive-augmentation BCI trial approvalpre #2 · pending · 2032-01-01 — First FDA full-market approval (non-IDE) for any consumer-targeted invasive BCIpre #1 · pending · 2032-12-31 — Pediatric BCI trial (under 18) approval by FDA or equivalent regulatorcascade #1 · pending · 2035-06-16 — Cumulative invasive BCI implant population exceeds 100,000 globallycascade #2 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040cascade #3 · pending · 2046-07-24 — Combustion engines largely gone in 20 years but world will be very differentcascade #4 · pending · 2048-08-06 — Humans will be demonstrably less safe than autonomous drivers (within 25 years, not 15)cascade #5 · pending · 2063-06-17 — Under a certain age (40-50) life expectancy is infinity due to longevity escape velocity.cascade #6 · pending · 2063-06-21 — Peter's 14-year-old son Milan will never get a driver's license.pre #6 · hit · 2026-02-19 — VITARI pre-orders open H1 2026pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2026-09-30 — First VITARI commercial shipment in H2 2026cascade #2 · pending · 2026-12-15 — Independent customer benchmarks confirm $100/genome at >=Q30 90%cascade #3 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #4 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.cascade #5 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #6 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.pre #6 · pending · 2027-04-18 — Q1 window check-in (25%)pre #5 · pending · 2027-11-01 — State-level lab-grown meat bans repealed or struck downpre #4 · pending · 2028-03-31 — Cultivated meat production cost falls below $20/lb wholesalepre #3 · pending · 2028-04-06 — Q2 window check-in (50%)pre #2 · pending · 2029-03-26 — Q3 window check-in (75%)pre #1 · pending · 2029-09-15 — Cultivated meat captures >1% of US ground meat retail dollarspre #6 · overdue · 2026-02-26 — Q1 window check-in (25%)pre #5 · overdue · 2026-04-23 — Q2 window check-in (50%)pre #4 · hit · 2026-04-30 — Q1 2026 Q1 funding alone reaches ~$1.94B aggregatepre #3 · overdue · 2026-05-17 — Mega-round (>=$200M) in longevity therapeutics announced in 2026pre #2 · pending · 2026-06-18 — Q3 window check-in (75%)pre #1 · pending · 2026-07-31 — Q1 2026 longevity funding rounds disclose mid-year totalscascade #1 · pending · 2026-12-15 — First IPO or major exit by longevity-pure-play in 2026cascade #2 · pending · 2027-02-28 — 2026 full-year longevity VC reaches $12B floorcascade #3 · pending · 2029-01-31 — Colossal gene editing will reach thousands of edits (up from current hundreds)cascade #4 · pending · 2070-06-17 — Infinite longevity is coming for this generation of kids.pre #6 · pending · 2026-10-31 — Diamandis Abundance360 Longevity Trip 2026 confirms market thesispre #5 · pending · 2028-03-16 — Major pharma cap-ex reallocation toward longevity / aging programspre #4 · pending · 2028-09-30 — First aging-as-disease ICD-11 code adoption by major payorpre #3 · pending · 2030-02-07 — Q1 window check-in (25%)pre #2 · pending · 2030-03-17 — Q2 window check-in (50%)pre #1 · pending · 2030-04-24 — Q3 window check-in (75%)pre #6 · pending · 2027-05-07 — Q2 window check-in (50%)pre #5 · pending · 2027-06-30 — First Big Pharma >$5B acquisition explicitly framed as 'longevity' enters announcedpre #4 · pending · 2027-12-31 — First senolytic candidate hits Phase 3 readoutpre #3 · pending · 2028-01-07 — Q3 window check-in (75%)pre #2 · pending · 2028-01-20 — Three or more top-15 pharmas publicly disclose longevity-asset acquisitionspre #1 · pending · 2028-06-30 — FDA grants formal qualified guidance on aging biomarker for clinical trial endpointscascade #1 · pending · 2070-06-17 — Infinite longevity is coming for this generation of kids.pre #6 · pending · 2028-12-31 — AI-designed aging-reversal compound enters human trialpre #5 · pending · 2029-03-31 — Scenario fires: AGI mid: Kurzweil 2029 pathpre #4 · pending · 2029-12-31 — Annual healthy-LE gain crosses 0.5 year per calendar yearpre #3 · pending · 2030-07-02 — First demonstrated whole-organ regeneration in human trialpre #2 · pending · 2031-05-17 — Biological-age reversal demonstrated in healthy-cohort RCTpre #1 · pending · 2033-05-16 — Healthy life-expectancy reaches 1.0 year per calendar year (LEV operational)cascade #1 · pending · 2036-08-14 — People will be on Mars within 10 yearscascade #2 · pending · 2036-08-24 — Mass driver on the moon within 10 yearscascade #3 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #4 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow.pre #6 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #5 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #4 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026).pre #3 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #2 · pending · 2028-03-16 — Mouse whole-brain connectome project funded at >$500Mpre #1 · pending · 2032-07-01 — First whole-mouse-brain connectome publicationcascade #1 · pending · 2033-12-15 — First running mouse whole-brain emulationcascade #2 · pending · 2036-07-30 — Human plumbers are safe for at least 10 years and probably significantly longercascade #3 · pending · 2036-08-14 — People will be on Mars within 10 yearscascade #4 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #5 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow.cascade #6 · pending · 2040-07-01 — First whole-human-brain connectome releasedpre #5 · hit · 2026-03-15 — Eon Systems demonstrates whole-fly multi-behavior emulationpre #4 · overdue · 2026-05-29 — Q1 window check-in (25%)pre #3 · pending · 2026-06-28 — Q2 window check-in (50%)pre #2 · pending · 2026-07-01 — Eon publishes Nature/bioRxiv paper on fly-brain emulationpre #1 · pending · 2026-07-28 — Q3 window check-in (75%)cascade #1 · pending · 2026-08-31 — Eon announces mouse-brain connectome target with timelinecascade #2 · pending · 2026-12-15 — Mouse connectome generation funding round announcedcascade #3 · pending · 2028-09-15 — First mouse brain region (e.g., visual cortex) emulated end-to-endpre #6 · hit · 2026-03-16 — First multi-behavior cyber-Drosophila body-brain integration (March 2026)pre #5 · pending · 2027-05-04 — Q1 window check-in (25%)pre #4 · pending · 2028-05-08 — Q2 window check-in (50%)pre #3 · pending · 2029-03-16 — Eon publishes mouse-brain partial emulation (~70M neurons)pre #2 · pending · 2029-05-13 — Q3 window check-in (75%)pre #1 · pending · 2029-07-01 — First peer-reviewed human cortical organoid + connectome integrationcascade #1 · pending · 2030-07-02 — First publicly announced commercial 'whole-brain digital twin' servicepre #6 · pending · 2026-12-31 — Healthcare humanoid robot market size hits $2.96B in 2026pre #5 · pending · 2026-12-31 — Robotic-assisted surgery market crosses $14B globallypre #4 · pending · 2027-03-17 — AI diagnostic systems (Aidoc, Viz.ai) integrated in >50% of US hospitalspre #3 · pending · 2027-03-19 — Q2 window check-in (50%)pre #2 · pending · 2027-08-28 — Q3 window check-in (75%)pre #1 · pending · 2027-12-16 — Optimus / humanoid surgery demonstration on cadaver or live procedurecascade #1 · pending · 2028-11-30 — Universal access to AI-doctor better than richest-person care NOT achieved by 2028-11-30pre #6 · pending · 2027-10-01 — Q2 window check-in (50%)pre #5 · pending · 2028-01-01 — FDA clearance of AI-as-medical-device for back pain triage or treatmentpre #4 · pending · 2028-04-30 — Major payer covers AI-driven back-pain therapypre #3 · pending · 2028-06-17 — Q3 window check-in (75%)pre #2 · pending · 2028-08-30 — Neuralink or competitor BCI receives FDA approval for chronic-pain indicationpre #1 · pending · 2029-03-01 — Population-scale outcomes evidence: AI back-pain interventions show >30% improvement vs SOCpre #6 · pending · 2027-03-27 — Q1 window check-in (25%)pre #5 · pending · 2027-08-01 — Colossal publishes peer-reviewed paper on novel-trait genetic engineering (beyond ancestral resurrection)pre #4 · pending · 2028-02-22 — Q2 window check-in (50%)pre #3 · pending · 2028-09-30 — First woolly mammoth born to Asian elephant surrogatepre #2 · pending · 2029-01-19 — Q3 window check-in (75%)pre #1 · pending · 2029-07-01 — Colossal or competitor announces first chimeric/de-novo designer creature program (e.g., novel mammal with non-ancestralcascade #1 · pending · 2030-09-15 — First reportable engineering of a 'novel creature' (significantly outside species ancestor) in mammal or birdpre #6 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026).pre #5 · pending · 2026-12-15 — Isomorphic Labs pipeline expands to 17+ active programs with Eli Lilly and Novartis partnerships in mid-trialspre #4 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump adpre #3 · pending · 2029-09-15 — First AI-designed drug receives FDA approval (any indication, primary structure designed by frontier model)pre #2 · pending · 2030-04-01 — First 'virtual cell' (full molecular-state predictive simulation) demonstrated for clinical-grade intervention modelingpre #1 · pending · 2031-03-17 — Cumulative AI-designed drug approvals reach 10+ across major disease categoriescascade #1 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #2 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #3 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #4 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve ecascade #5 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040pre #6 · hit · 2026-04-29 — Nvidia became the world's first $5 trillion company (late 2025), operating a near-monopoly on advanced AI chips.pre #5 · hit · 2026-04-29 — Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinnedpre #4 · hit · 2026-04-29 — Nvidia's Arizona-based TSMC factory successfully fabricated cutting-edge semiconductors on US soil for first time in decpre #3 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #2 · pending · 2026-06-25 — Nvidia agreed to remit 15% of China chip-sale revenue directly to US government in exchange for reversing specific AI chpre #1 · pending · 2028-01-01 — First FDA pivotal approval where Phase 3 control arm is fully replaced by digital twincascade #1 · pending · 2030-05-17 — First sub-indication approved with zero traditional clinical trials (computational + Bayesian only)cascade #2 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #3 · pending · 2036-03-23 — World will have 10x more wealth around 2034-2036cascade #4 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040cascade #5 · pending · 2063-06-17 — Under a certain age (40-50) life expectancy is infinity due to longevity escape velocity.cascade #6 · pending · 2063-06-21 — Peter's 14-year-old son Milan will never get a driver's license.pre #3 · pending · 2027-12-24 — Q1 window check-in (25%)pre #2 · pending · 2029-08-19 — Q2 window check-in (50%)pre #1 · pending · 2031-04-14 — Q3 window check-in (75%)pre #6 · pending · 2027-06-16 — First sovereign government signs paid contract with Colossal for endangered-species genetic rescuepre #5 · pending · 2027-06-16 — Colossal Biovault reaches biobanking milestone (>1000 endangered-species cell lines stored)pre #4 · pending · 2027-09-16 — Australian government allocates funding for thylacine reintroduction feasibility studypre #3 · pending · 2027-10-15 — Q2 window check-in (50%)pre #2 · pending · 2028-05-01 — Multi-government consortium model emerges (UN/CITES adjacent) with paid Colossal servicespre #1 · pending · 2028-07-08 — Q3 window check-in (75%)pre #6 · pending · 2027-06-16 — Colossal's de-extinction portfolio reaches 8+ named species (mammoth, dire wolf, dodo, thylacine, moa, bluebuck, +2)pre #5 · pending · 2027-10-15 — Q2 window check-in (50%)pre #4 · pending · 2028-01-01 — Colossal publishes first artificial-womb feasibility study for elephant-class embryospre #3 · pending · 2028-03-16 — First mammoth calf born to elephant surrogate (or via artificial womb)pre #2 · pending · 2028-04-30 — Computer-vision-based embryo selection deployed at scale (>1000 embryos screened/year)pre #1 · pending · 2028-07-07 — Q3 window check-in (75%)pre #6 · hit · 2026-02-13 — Founder publicly reaffirms 2028 mammoth target at major venuepre #5 · hit · 2026-04-30 — Sixth de-extinction species (bluebuck) added to portfoliopre #4 · pending · 2026-10-15 — Q1 window check-in (25%)pre #3 · pending · 2026-12-15 — First successful mammoth-edited Asian elephant embryo transferpre #2 · pending · 2027-04-01 — Q2 window check-in (50%)pre #1 · pending · 2027-09-16 — Q3 window check-in (75%)cascade #1 · pending · 2028-07-01 — First viable mammoth-trait Asian elephant calf birth (22-month gestation)pre #2 · hit · 2025-01-30 — Khaleesi (third direwolf, female) birth announcementpre #1 · hit · 2025-10-01 — Direwolf pack social-development milestone (1-year birthday update)cascade #1 · hit · 2026-04-30 — Colossal announces new de-extinct species (bluebuck or other)cascade #2 · pending · 2026-12-15 — Colossal announces additional direwolves (4th-onwards)cascade #3 · pending · 2028-03-16 — Woolly mammoth first birth (2028 target tracking)pre #6 · hit · 2026-02-12 — Engineered PETase enzyme paper (Bhattacharya et al.) published in FEBS Journal — highly active polyester degradationpre #5 · pending · 2026-07-20 — Q1 window check-in (25%)pre #4 · pending · 2026-10-10 — Q2 window check-in (50%)pre #3 · pending · 2026-12-15 — PETase/MHETase variant with gut-compatible pH/temperature window (pH 1-7, 37C) demonstratedpre #2 · pending · 2026-12-31 — Q3 window check-in (75%)pre #1 · pending · 2027-03-17 — First published in-vivo (animal model) study of orally-delivered plastic-degrading enzyme on microplastic absorptioncascade #1 · pending · 2027-05-17 — Supplement company / startup announces clinical work toward microplastic-degrading oral productpre #6 · pending · 2027-06-29 — Q2 window check-in (50%)pre #5 · pending · 2027-06-30 — Breaking publishes preclinical paper or whitepaper on human-body microplastic supplementpre #4 · pending · 2027-09-30 — Breaking environmental product (plastic-degrading microbe) hits commercial scale milestonepre #3 · pending · 2028-01-13 — First peer-reviewed human RCT data on a microplastic-clearance interventionpre #2 · pending · 2028-01-27 — Q3 window check-in (75%)pre #1 · pending · 2028-03-31 — Breaking launches DTC supplement product or files IND with FDApre #6 · pending · 2027-05-02 — Colossal announces 4th-6th spinout under 'dozen companies' planpre #5 · pending · 2027-05-02 — Colossal raises follow-on at ≥$15B valuationpre #4 · pending · 2027-06-16 — Form Bio reaches $100M ARR or $1B valuation milestonepre #3 · pending · 2027-08-01 — Breaking (plastic-degradation spinout) commercial pilot launchedpre #2 · pending · 2027-10-02 — Q3 window check-in (75%)pre #1 · pending · 2028-01-01 — First Colossal spinout reaches IPO or >=$1B unicorn valuationcascade #1 · pending · 2028-12-31 — Colossal spinout count reaches 12 companies (Diamandis claim)pre #6 · pending · 2026-11-15 — Colossal mammoth embryos ready for elephant surrogate implantation by end of 2026pre #5 · pending · 2027-05-02 — EXTEND artificial womb begins first-in-human clinical trials for premature infantspre #4 · pending · 2027-06-07 — Q1 window check-in (25%)pre #3 · pending · 2028-07-01 — First woolly mammoth calf born from edited Asian elephant surrogatepre #2 · pending · 2028-07-15 — Q2 window check-in (50%)pre #1 · pending · 2029-08-23 — Q3 window check-in (75%)cascade #1 · pending · 2030-10-01 — Productionized de-extinction species via artificial wombs (event)pre #6 · overdue · 2026-03-16 — Q2 window check-in (50%)pre #5 · overdue · 2026-04-01 — Viagen acquisition integration enables productionized cloning pipelinepre #4 · overdue · 2026-04-01 — Government MoU or co-funded program announced for endangered-species cloningpre #3 · hit · 2026-04-20 — Colossal cloned 4 red wolves announcedpre #2 · overdue · 2026-04-22 — Q3 window check-in (75%)pre #1 · hit · 2026-04-30 — Bluebuck de-extinction project announcedcascade #1 · pending · 2026-07-02 — Mexican government CONANP partnership advances vaquita biobankcascade #2 · pending · 2029-01-31 — Colossal gene editing will reach thousands of edits (up from current hundreds)cascade #3 · pending · 2070-06-17 — Infinite longevity is coming for this generation of kids.pre #6 · pending · 2027-10-01 — First mammoth-edited embryo implanted in elephant surrogatepre #5 · pending · 2028-06-05 — Q2 window check-in (50%)pre #4 · pending · 2028-12-31 — Synthetic biology demonstration of multi-locus designer trait combination (>100 simultaneous edits)pre #3 · pending · 2029-06-15 — First live mammoth birth (or fail) — primary milestone for de-extinction technologypre #2 · pending · 2029-06-24 — Q3 window check-in (75%)pre #1 · pending · 2030-07-02 — Major regulatory framework explicitly addresses designer organism creationcascade #1 · pending · 2032-12-31 — First synthetic-genome-derived mammal demonstrating non-natural trait combinationpre #6 · pending · 2027-09-16 — First successful CRISPR-engineered chytrid-resistant frog line published in peer-reviewed journalpre #5 · pending · 2028-01-12 — Q2 window check-in (50%)pre #4 · pending · 2028-03-31 — Colossal Foundation or partner publishes Bd-resistance gene multiplex editing protocol in great spotted tree frog or corpre #3 · pending · 2028-11-18 — Q3 window check-in (75%)pre #2 · pending · 2029-03-31 — First field release of gene-edited chytrid-resistant amphibian population approved by national wildlife regulatorpre #1 · pending · 2029-09-15 — IUCN Red List downlists at least one chytrid-affected species citing genetic-rescue interventionpre #6 · overdue · 2026-04-12 — Colossal's 'Lamm $5.4T invasive-species' narrative is repeatedly cited by analystspre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2026-12-15 — Colossal-affiliated Tropic Biosciences reports disease-resistant crop deploymentcascade #2 · pending · 2026-12-15 — Industry analyst sizes the disease-resistant ag-biotech market explicitlycascade #3 · pending · 2027-03-17 — Colossal Foundation EEHV mRNA vaccine expands to additional zoos/herdscascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #5 · pending · 2027-10-01 — First publicly traded comp pure-play in disease-resistant biotech announces revenuecascade #6 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.pre #6 · pending · 2026-12-14 — Q1 window check-in (25%)pre #5 · pending · 2026-12-15 — Gene drive screwworm efficiency demonstrated in labpre #4 · pending · 2026-12-31 — USDA south Texas sterile fly facility operational (100M flies/wk)pre #3 · pending · 2027-07-30 — Q2 window check-in (50%)pre #2 · pending · 2028-01-01 — Regulatory framework for gene drive insect release proposedpre #1 · pending · 2028-03-14 — Q3 window check-in (75%)cascade #1 · pending · 2028-12-31 — First field/contained release of gene-drive screwwormcascade #2 · pending · 2029-03-17 — Measurable population suppression of screwworm in target zonepre #6 · overdue · 2026-05-30 — Colossal has major announcements coming this year with a local government on productionizing cloning of endangered specipre #5 · pending · 2026-08-14 — Longevity VC market expected to grow from $8.5B in 2024 to $12-18B in 2026.pre #4 · pending · 2026-09-08 — Colossal DNA synthesis delivery will reach 20x the largest prior delivery by end of 2026pre #3 · pending · 2026-12-15 — Mammoth-like elephant cell line crosses 100 simultaneous editspre #2 · pending · 2027-05-02 — Mammoth-like Asian elephant embryo producedpre #1 · pending · 2028-06-15 — Colossal demonstrates ≥500 simultaneous edits in any cell linecascade #1 · pending · 2029-03-01 — Colossal achieves ≥1,000 simultaneous edits across genomecascade #2 · pending · 2070-06-17 — Infinite longevity is coming for this generation of kids.pre #6 · pending · 2027-10-17 — Q2 window check-in (50%)pre #5 · pending · 2028-01-01 — First peer-reviewed publication applying Colossal's multiplex-edit pipeline to human-disease modelpre #4 · pending · 2028-05-03 — Colossal/spinout signs licensing deal with established biopharma for gene-editing platformpre #3 · pending · 2028-05-03 — Colossal IPO or strategic exit unlocks separate human-therapeutics valuationpre #2 · pending · 2028-07-11 — Q3 window check-in (75%)pre #1 · pending · 2028-08-18 — First IND (Investigational New Drug) filing or pre-IND meeting for Colossal-derived human therapypre #6 · hit · 2026-04-12 — Colossal publicly announces 5x prior-largest DNA delivery already achievedpre #5 · hit · 2026-04-15 — Colossal makes Bluebuck de-extinction breakthrough disclosurepre #4 · overdue · 2026-05-06 — Q2 window check-in (50%)pre #3 · pending · 2026-07-01 — Colossal demonstrates DNA delivery in small mammal first as scaling steppre #2 · pending · 2026-07-07 — Q3 window check-in (75%)pre #1 · pending · 2026-08-16 — Form Bio (Colossal spinout) commercializes large DNA delivery technologycascade #1 · pending · 2026-11-15 — Colossal claims 20x prior-largest DNA synthesis delivery by year-end 2026cascade #2 · pending · 2026-12-15 — Peer review or publication validates Colossal's large-cassette delivery techniquecascade #3 · pending · 2029-01-31 — Colossal gene editing will reach thousands of edits (up from current hundreds)cascade #4 · pending · 2070-06-17 — Infinite longevity is coming for this generation of kids.pre #6 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #5 · pending · 2026-12-15 — Astromech reaches first paying customer or major partnership outside Colossalpre #4 · pending · 2027-05-01 — Astromech valuation step-up and Series B raisepre #3 · pending · 2027-05-02 — Colossal publishes peer-reviewed paper on its synthetic-biology modeling stackpre #2 · pending · 2027-08-01 — Form Bio platform reports cross-pharma adoption metricspre #1 · pending · 2028-03-16 — Mammoth/thylacine de-extinction proof-of-concept embryo or birthcascade #1 · pending · 2030-04-18 — Dario Amodei will solve most/all neurological diseases by end of decadecascade #2 · pending · 2030-10-10 — Europa Clipper will arrive at Jupiter in 2030, conducting 50 passes near Europa.cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #4 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040cascade #5 · pending · 2063-06-21 — Peter's 14-year-old son Milan will never get a driver's license.pre #6 · pending · 2027-06-16 — Q2 window check-in (50%)pre #5 · pending · 2027-06-30 — Colossal publishes peer-reviewed paper on hydrogel/microfluidic embryo culture for elephant ARTpre #4 · pending · 2027-12-15 — First US fertility clinic adopts microfluidic embryo culture commerciallypre #3 · pending · 2027-12-31 — Colossal commercial spinout for human IVF tech announcedpre #2 · pending · 2028-01-08 — Q3 window check-in (75%)pre #1 · pending · 2028-03-31 — ASRM or ESHRE recognizes new IVF embryo grading scale tied to microfluidic biomarkerspre #6 · pending · 2027-11-01 — IUCN formally endorses synthetic-biology assisted-evolution for conservationpre #5 · pending · 2028-03-16 — First gene-edited endangered animal released into wild monitored habitatpre #4 · pending · 2028-04-11 — Q2 window check-in (50%)pre #3 · pending · 2028-09-15 — Heat-tolerant coral or amphibian gene-edit deployed at reef/wetland scalepre #2 · pending · 2029-03-16 — Treaty-level framework on environmental release of edited organisms enters forcepre #1 · pending · 2029-04-02 — Q3 window check-in (75%)pre #6 · pending · 2027-02-10 — Q1 window check-in (25%)pre #5 · pending · 2027-11-24 — Q2 window check-in (50%)pre #4 · pending · 2028-03-16 — First woolly mammoth birth occurspre #3 · pending · 2028-09-06 — Q3 window check-in (75%)pre #2 · pending · 2028-09-15 — Regulatory approval secured for first reintroduction sitepre #1 · pending · 2029-03-31 — First de-extincted species pilot release into managed habitatpre #6 · hit · 2026-04-12 — Colossal publicly describes gene drive as reversible (rollback feature documented)pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2026-12-15 — Peer-reviewed publication on Colossal's reversible gene drive containment mechanismcascade #2 · pending · 2027-03-17 — Independent demonstration of rollback in caged trialcascade #3 · pending · 2027-03-17 — Critical scientific pushback (rebuttal paper questioning rollback feasibility)cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #5 · pending · 2027-08-01 — Regulatory approval (USDA APHIS / NZ EPA / Australia OGTR) for first wild-release pilotcascade #6 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.pre #6 · pending · 2026-10-29 — Q1 window check-in (25%)pre #5 · pending · 2027-03-17 — Colossal artificial-womb spinout announcedpre #4 · pending · 2027-04-30 — Q2 window check-in (50%)pre #3 · pending · 2027-09-16 — Breaking Inc. (plastics microbe spinout) reaches commercial deploymentpre #2 · pending · 2027-10-29 — Q3 window check-in (75%)pre #1 · pending · 2028-01-01 — Colossal announces 5th technology spinoutpre #6 · pending · 2028-07-01 — Second African nation re-permits gene-drive Anopheles trialpre #5 · pending · 2028-09-09 — Q1 window check-in (25%)pre #4 · pending · 2029-07-01 — First gene-drive eradication targeting an invasive species achieves measurable population suppressionpre #3 · pending · 2030-07-02 — WHO/CBD adopts standardized gene-drive containment protocol distinguishing native vs invasivepre #2 · pending · 2031-01-21 — Q2 window check-in (50%)pre #1 · pending · 2033-06-02 — Q3 window check-in (75%)pre #6 · pending · 2026-11-29 — Colossal Biosciences announces second sovereign-state Biovault partnership (post-UAE)pre #5 · pending · 2027-02-21 — Q2 window check-in (50%)pre #4 · pending · 2027-05-02 — Dubai Museum of the Future BioVault facility opens to public visitorspre #3 · pending · 2027-05-02 — Colossal banks first 100 of the 10,000-species targetpre #2 · pending · 2027-07-19 — Q3 window check-in (75%)pre #1 · pending · 2027-08-01 — Colossal Series D or pre-IPO financing round closes at >=$10B valuationcascade #1 · pending · 2028-01-01 — Third or more sovereign Biovault site under construction simultaneously (network confirmation)cascade #2 · pending · 2029-12-31 — First de-extinction or rewilded species sourced from BioVault genetic materialpre #6 · pending · 2026-08-27 — Q1 window check-in (25%)pre #5 · pending · 2026-12-25 — Q2 window check-in (50%)pre #4 · pending · 2027-01-30 — Dubai facility opens with public-facing living-lab programspre #3 · pending · 2027-04-24 — Q3 window check-in (75%)pre #2 · pending · 2027-05-01 — First UAE biovault species samples archived (≥1000 specimens)pre #1 · pending · 2027-07-02 — Colossal expands to second international living-lab sitepre #6 · pending · 2027-05-04 — Q1 window check-in (25%)pre #5 · pending · 2027-12-31 — Synthetic biology total market crosses $50B annual revenuepre #4 · pending · 2028-03-16 — AI-designed protein / molecule receives first FDA new molecular entity approvalpre #3 · pending · 2028-05-07 — Q2 window check-in (50%)pre #2 · pending · 2029-05-11 — Q3 window check-in (75%)pre #1 · pending · 2029-07-01 — Synthetic biology firm achieves $100B+ market capcascade #1 · pending · 2032-12-31 — Synthetic biology revenue equals 1% of US GDP (~$300B/yr)pre #6 · pending · 2026-12-31 — Carbios Longlaville facility online (50K t/yr PET)pre #5 · pending · 2027-05-02 — Breaking secures Series A funding ≥$50Mpre #4 · pending · 2027-09-01 — Q2 window check-in (50%)pre #3 · pending · 2028-03-16 — Breaking demonstrates pilot-scale facility for ≥1 non-PET plasticpre #2 · pending · 2028-05-03 — Q3 window check-in (75%)pre #1 · pending · 2028-09-15 — Independent benchmark confirms Breaking enzymes outperform PETase variants on rate/areapre #6 · pending · 2027-05-02 — First viable northern-white-rhino embryo transfer pregnancy maintained past 90 days in southern white rhino surrogatepre #5 · pending · 2027-08-19 — Q1 window check-in (25%)pre #4 · pending · 2028-06-15 — Functional oocytes from northern-white-rhino induced pluripotent stem cells produced (synthetic genetic diversity proof)pre #3 · pending · 2028-12-07 — Q2 window check-in (50%)pre #2 · pending · 2029-06-15 — First northern white rhino calf born from BioRescue embryo + southern white rhino surrogatepre #1 · pending · 2030-03-28 — Q3 window check-in (75%)cascade #1 · pending · 2031-07-18 — Synthetic-genetic-diversity engineering applied to NWR — first calf born with iPSC-derived gametespre #6 · pending · 2028-10-25 — Q1 window check-in (25%)pre #5 · pending · 2029-03-16 — Colossal announces no new pivot beyond de-extinction core (consistent w/ thesis)pre #4 · pending · 2029-03-31 — Colossal launches first calf (mammoth or thylacine equivalent)pre #3 · pending · 2031-04-22 — Q2 window check-in (50%)pre #2 · pending · 2032-01-01 — First scientifically validated reintroduction of de-extinct species into protected reservepre #1 · pending · 2033-10-17 — Q3 window check-in (75%)pre #6 · hit · 2026-04-14 — OpenAI x Novo Nordisk drug-discovery partnership announced (broader pharma platform)pre #5 · pending · 2027-03-21 — Q1 window check-in (25%)pre #4 · pending · 2028-02-10 — Q2 window check-in (50%)pre #3 · pending · 2028-03-31 — First repurposed off-patent compound from OpenAI program shows positive Alzheimer's biomarker signalpre #2 · pending · 2028-06-15 — First OpenAI-Foundation backed Alzheimer's drug candidate enters Phase 1 clinical trialpre #1 · pending · 2029-01-01 — Q3 window check-in (75%)cascade #1 · pending · 2030-07-02 — Spinout/IPO of any AI-pharma company launched from OpenAI Alzheimer's program crosses $10B valuationcascade #2 · pending · 2030-12-31 — First FDA approval of OpenAI-Foundation lineage Alzheimer's drugpre #6 · pending · 2026-12-15 — Arc Institute Virtual Cell Challenge 2026 results show >2x improvement over State baselinepre #5 · pending · 2027-03-17 — CZI rBio / TranscriptFormer next-gen model published with whole-cell perturbation predictionpre #4 · pending · 2027-03-17 — Nvidia or major cloud announces dedicated virtual-cell training compute partnershippre #3 · pending · 2028-01-01 — First peer-reviewed virtual-cell prediction validated wet-lab in independent academic studypre #2 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump adpre #1 · pending · 2029-06-15 — First FDA-acceptable in-silico virtual-cell experiment cited in IND submissioncascade #1 · pending · 2031-06-16 — Cascade: First drug program with discovery anchor in virtual-cell simulation enters Phase 1cascade #2 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve ecascade #6 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040pre #6 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #5 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #4 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)pre #3 · pending · 2027-05-02 — First E. coli whole-cell model with predictive accuracy on growth/metabolism publishedpre #2 · pending · 2028-06-15 — Compute time for 1 hour of cell biology drops from 6 days to <1 daypre #1 · pending · 2029-03-31 — First yeast (S. cerevisiae) whole-cell digital twin publishedcascade #1 · pending · 2030-07-31 — First mammalian (HeLa or hepatocyte) whole-cell simulation reaches publicationcascade #2 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve ecascade #6 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040pre #4 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)pre #3 · pending · 2027-10-22 — Q1 window check-in (25%)pre #2 · pending · 2029-08-12 — Q2 window check-in (50%)pre #1 · pending · 2031-06-03 — Q3 window check-in (75%)cascade #1 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow.pre #6 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #5 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)pre #4 · pending · 2027-03-17 — Pharma AI R&D spend >75% increase YoYpre #3 · pending · 2028-12-31 — AI-driven biotech aging-reversal compound enters Phase 1pre #2 · pending · 2030-07-02 — Multiple AI-designed drugs receive FDA approvalpre #1 · pending · 2032-12-31 — Healthy life-expectancy gain exceeds 1 year per calendar year sustainedcascade #1 · pending · 2034-06-16 — US life expectancy at birth crosses 90 yearscascade #2 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow.cascade #3 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040cascade #4 · pending · 2046-07-24 — Combustion engines largely gone in 20 years but world will be very differentpre #6 · pending · 2028-06-04 — Competitors that can match Figure's current capabilities are at least two years behind.pre #5 · pending · 2028-06-24 — AI will bulk-solve math, physical sciences, engineering, medicine, and material sciences.pre #4 · pending · 2028-07-01 — First AI-designed drug approved for any neurological indicationpre #3 · pending · 2028-07-10 — For the next few years more people will end up doing more work, not less (996 turns into 997).pre #2 · pending · 2028-07-21 — Figure is effectively sold out on its current customer base for the next two to three years.pre #1 · pending · 2028-08-10 — Two years from now, best AI will not be freely accessible — it will be withheld citing security/safety.cascade #1 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #2 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034.cascade #3 · pending · 2036-09-06 — Moon base will exist in 10 yearscascade #4 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve ecascade #5 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040pre #6 · hit · 2025-06-30 — Insilico Medicine Phase IIa positive results (TNIK inhibitor for IPF)pre #5 · hit · 2026-02-01 — Industry analyst report confirms 80-90% AI-drug Phase 1 success ratepre #4 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #3 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2027-03-17 — First AI-designed drug enters Phase III pivotal trialcascade #2 · pending · 2027-05-02 — Isomorphic Labs first IsoDDE molecule enters clinical trialscascade #3 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #4 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.cascade #5 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #6 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.pre #6 · pending · 2027-06-16 — Arc Institute or CZI Virtual Cell program releases >=10x scaled multimodal cell foundation modelpre #5 · pending · 2027-08-01 — First full-cell multimodal foundation model demonstrates causal-transport prediction across cell types in Nature/Sciencepre #4 · pending · 2028-01-14 — Q2 window check-in (50%)pre #3 · pending · 2028-09-15 — AI-designed perturbation prediction reaches AlphaFold-tier benchmark accuracy via classical computepre #2 · pending · 2028-11-21 — Q3 window check-in (75%)pre #1 · pending · 2028-12-14 — Major pharma signs >=$500M deal predicated on classical-scaled virtual-cell platform without quantum-computing dependencpre #6 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #5 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #4 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #3 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #2 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)pre #1 · pending · 2026-06-15 — First true n=1 personalized drug therapy approvedcascade #1 · pending · 2026-12-16 — n>=10 documented n=1 AI-designed therapies in patientscascade #2 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #3 · pending · 2027-07-02 — AI-designed drug discovery time falls to <12 months consistentlycascade #4 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.cascade #5 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #6 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.pre #6 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #5 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #4 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #3 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)pre #2 · overdue · 2026-05-27 — FDA Commissioner Makary departure, replacement, or announced leavepre #1 · overdue · 2026-05-27 — RFK Jr override of FDA decision becomes public or formalcascade #1 · pending · 2026-07-16 — Major FDA reorganization or RIF (reduction in force) announcementcascade #2 · pending · 2026-08-31 — Congressional hearing or bipartisan letter calls for FDA reformcascade #3 · pending · 2026-12-30 — Pharma industry lobbying for FDA leadership change escalates publiclycascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #5 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.cascade #6 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human pre #6 · hit · 2025-05-21 — Inaugural Enhanced Games scheduled for May 21-24, 2026 Las Vegaspre #5 · hit · 2025-05-21 — Gkolomeev posts unofficial 50m freestyle world record (20.89s) in Enhanced trialpre #4 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #3 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2026-05-22 — Enhanced Games inaugural competition delivered without major safety incidentcascade #2 · pending · 2026-05-22 — Enhanced 2026 produces >=2 records faster than current official world recordscascade #3 · pending · 2027-01-30 — Enhanced Games announces second edition with year-over-year mark improvementscascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #5 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.cascade #6 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2026-12-15 — Number of Neuralink human implants reaches 50+cascade #2 · pending · 2026-12-31 — Neuralink launches high-volume production with automated surgery in 2026cascade #3 · pending · 2026-12-31 — Neuralink Blindsight first patient trial begins (non-destructive read/write to cortex)cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #5 · pending · 2027-07-02 — First whole-brain emulation / connectome scan published from preserved tissuecascade #6 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out)cascade #1 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled.cascade #2 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds.cascade #3 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #4 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033.cascade #5 · pending · 2033-08-10 — ASI will arrive within 2 years to 5 years to this next decadepre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cupre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025.pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream.pre #1 · hit · 2026-04-29 — Professional Robotics League first US match on April 19, 2026 in Bostoncascade #1 · pending · 2026-07-20 — Optimus 3 production starts summer 2026cascade #2 · pending · 2026-08-15 — Tesla Optimus 3 begins production at Fremont (summer 2026)cascade #3 · pending · 2027-03-17 — First peer-reviewed paper on multi-modal embodied 'general' robot intelligencecascade #4 · pending · 2027-06-17 — Fast food chains will bring in humanoid robots very shortly to replace workers.cascade #5 · pending · 2027-09-03 — Amazon Zoox Robotaxi will launch in LA in 2027cascade #6 · pending · 2027-09-16 — Genetic-engineering policy debate around human germline editing intensifiespre #6 · pending · 2031-11-30 — Scenario fires: AGI slow: Schmidt/Hassabis 5-10 year pathpre #5 · pending · 2031-12-05 — Q1 window check-in (25%)pre #4 · pending · 2032-07-01 — First AI-designed therapeutic receives FDA approval (any indication)pre #3 · pending · 2033-09-15 — Cascade: AI-driven biology research accelerates such that publication-rate compression of ~10x reported in major journalpre #2 · pending · 2033-11-07 — Q2 window check-in (50%)pre #1 · pending · 2035-10-11 — Q3 window check-in (75%)pre #3 · pending · 2029-04-29 — Q1 window check-in (25%)pre #2 · pending · 2030-08-27 — Q2 window check-in (50%)pre #1 · pending · 2031-12-25 — Q3 window check-in (75%)pre #5 · hit · 2025-12-31 — Colossal BioVault Dubai partnership officially announcedpre #4 · pending · 2026-12-15 — Initial 100 most-endangered species onboarded to BioVaultpre #3 · pending · 2027-02-04 — Q1 window check-in (25%)pre #2 · pending · 2027-03-11 — Q2 window check-in (50%)pre #1 · pending · 2027-04-14 — Q3 window check-in (75%)cascade #1 · pending · 2027-07-02 — Dubai facility opens to public at Museum of the Futurecascade #2 · pending · 2030-07-02 — 10,000 species genetic preservation milestone reachedcascade #3 · pending · 2032-03-16 — Functional resurrection of keystone species achieved using AI + synthetic biologypre #6 · pending · 2031-07-02 — Phase 1/2 trial readout for thrombolysis or targeted oncology nanorobot platform demonstrates safety + efficacy in humanpre #5 · pending · 2031-08-22 — Q1 window check-in (25%)pre #4 · pending · 2031-12-31 — Demonstration of autonomous in-vivo cellular damage detection or repair (not just delivery) in mammalian model — requirepre #3 · pending · 2033-04-12 — Q2 window check-in (50%)pre #2 · pending · 2034-07-02 — Cascade: regulatory framework for autonomous in-body nanodevices established (FDA combination product or new device pathpre #1 · pending · 2034-12-02 — Q3 window check-in (75%)pre #6 · pending · 2029-03-31 — Continuous biological surveillance via wearables exceeds 1B active users globallypre #5 · pending · 2030-04-19 — Q2 window check-in (50%)pre #4 · pending · 2030-07-02 — First FDA-approved AI-designed therapeutic targeting an aging hallmark (senescence, mitochondrial dysfunction, or epigenpre #3 · pending · 2031-04-01 — Quantum-accelerated genomics workflow demonstrates >100x speedup over classical for variant calling at population scalepre #2 · pending · 2031-12-12 — Q3 window check-in (75%)pre #1 · pending · 2033-07-01 — Mainstream press declares 'longevity escape velocity' as imminent or partially achievedpre #6 · pending · 2029-07-01 — FDA approval of any AI-discovered/designed cancer therapeuticpre #5 · pending · 2029-07-01 — First disease-modifying Alzheimer's therapeutic with AI-designed mechanism enters Phase 2pre #4 · pending · 2031-12-30 — Q1 window check-in (25%)pre #3 · pending · 2032-12-28 — Q2 window check-in (50%)pre #2 · pending · 2033-07-02 — Cascade: First FDA approval claim of AI-discovered Alzheimer's disease-modifying therapeutic with measurable cognitive bpre #1 · pending · 2033-12-26 — Q3 window check-in (75%)cascade #1 · pending · 2070-06-17 — Infinite longevity is coming for this generation of kids.pre #6 · hit · 2025-01-07 — FDA proposes 7-step credibility assessment framework for AI modelspre #5 · overdue · 2025-05-25 — Q1 window check-in (25%)pre #4 · overdue · 2025-10-11 — Q2 window check-in (50%)pre #3 · hit · 2026-02-15 — Industry critical reviews of FDA draft published (peer-reviewed)pre #2 · overdue · 2026-02-27 — Q3 window check-in (75%)pre #1 · overdue · 2026-05-16 — FDA finalizes AI drug-submission guidance by Q2 2026 (per agency timeline)cascade #1 · pending · 2026-09-15 — Materially advanced revised draft published if not finalizedcascade #2 · pending · 2027-01-30 — First AI-supported drug NDA approved using credibility frameworkpre #5 · overdue · 2025-09-10 — Q1 window check-in (25%)pre #4 · overdue · 2026-01-28 — ISM8969 FDA IND clearancepre #3 · overdue · 2026-02-20 — Q2 window check-in (50%)pre #2 · pending · 2026-08-02 — Q3 window check-in (75%)pre #1 · pending · 2026-09-15 — First patient dosed in Isomorphic Phase 1 oncology trialcascade #1 · pending · 2027-05-02 — Peer AI-designed drugs (Insilico, Recursion, BenevolentAI) report Phase 1 progresscascade #2 · pending · 2027-06-30 — Phase 1 dose escalation (first dose level) completioncascade #3 · pending · 2027-09-15 — Initial Phase 1 readout (top-line efficacy / safety)pre #6 · hit · 2026-03-04 — Colossal Biosciences confirms 2028 woolly mammoth birth target (Mar 2026)pre #5 · pending · 2026-07-25 — Q1 window check-in (25%)pre #4 · pending · 2026-10-20 — Q2 window check-in (50%)pre #3 · pending · 2026-10-30 — Asian elephant ovum retrieval / IVF protocol validated (peer-reviewed publication)pre #2 · pending · 2027-01-14 — Q3 window check-in (75%)pre #1 · pending · 2027-01-30 — Colossal announces edited-elephant-cell line with full mammoth gene-edit suite ready for embryo creationcascade #1 · pending · 2027-05-17 — First mammoth-edit embryo created in vitro (lab-stage milestone)cascade #2 · pending · 2027-09-15 — First embryo transferred into elephant surrogate by end-2027 (prediction direct event)cascade #3 · pending · 2028-10-04 — Colossal produces a live mammoth-like elephant calf by end 2028pre #6 · pending · 2027-04-11 — Colossal completes mammoth embryo transfer into an elephant surrogate by end 2027pre #5 · pending · 2027-04-30 — Successful pregnancy confirmed via ultrasound at >=4 months post-transferpre #4 · pending · 2027-05-17 — Backup ET into 2nd or 3rd surrogate completed (redundancy strategy)pre #3 · pending · 2028-03-10 — Q1 window check-in (25%)pre #2 · pending · 2028-05-18 — Q2 window check-in (50%)pre #1 · pending · 2028-07-26 — Q3 window check-in (75%)pre #6 · pending · 2026-09-15 — Thylacine scientific-progress milestone announcement (per Colossal commitment 'before end of year')pre #5 · pending · 2026-10-20 — Q1 window check-in (25%)pre #4 · pending · 2027-04-11 — Q2 window check-in (50%)pre #3 · pending · 2027-10-01 — Q3 window check-in (75%)pre #2 · pending · 2027-11-16 — Bluebuck embryo creation + roan-surrogate transfer (resolution criterion satisfaction)pre #1 · pending · 2028-03-16 — Either Bluebuck OR Thylacine reaches active embryo-transfer pipeline before window closecascade #1 · pending · 2029-05-02 — Live Bluebuck calf born — full de-extinction success (cascade beyond pack window)pre #6 · pending · 2027-09-16 — DARPA / BARDA / NIH multi-year synbio biomanufacturing program >$1B announcedpre #5 · pending · 2027-11-01 — AI-designed enzyme commercially licensed to Top-20 pharma or specialty chemical co.pre #4 · pending · 2027-12-16 — First cell-programmed industrial product passes $100M annual revenuepre #3 · pending · 2028-01-30 — Q2 window check-in (50%)pre #2 · pending · 2028-09-15 — Cell-programmed environmental biosensor deployed at city-scalepre #1 · pending · 2029-02-12 — Q3 window check-in (75%)pre #6 · pending · 2027-12-14 — Q2 window check-in (50%)pre #5 · pending · 2027-12-31 — Scenario fires: 50GW dedicated AI/data center grid by Dec 2027pre #4 · pending · 2028-07-01 — Sub-cent solar PPA signed in any utility-scale US bid roundpre #3 · pending · 2028-09-15 — Synthetic biology / bioprocessing market crosses $50B annual revenuepre #2 · pending · 2028-12-04 — Q3 window check-in (75%)pre #1 · pending · 2028-12-31 — LanzaTech reaches 30,000 metric ton/year commercial-scale protein productioncascade #1 · pending · 2030-06-15 — Cascade: first gigaton-scale bio-industrial production milestone (>=1Gt CO2-equivalent feedstock processed)pre #6 · hit · 2025-04-30 — rWGS diagnostic timeline compressed to 24-26 hours documentedpre #5 · hit · 2025-09-15 — MPSE automation surfaces NICU patients within 48h of admissionpre #4 · overdue · 2025-09-12 — Q2 window check-in (50%)pre #3 · hit · 2025-04-30 — rWGS diagnostic yield exceeds 50% in NICU populationpre #2 · overdue · 2026-01-17 — Q3 window check-in (75%)pre #1 · overdue · 2026-03-17 — Oral GLP-1 (Wegovy class) approvedcascade #1 · pending · 2026-06-16 — First FDA-cleared NICU rWGS diagnostic with <8h turnaroundpre #6 · pending · 2026-09-15 — Form Bio platform expands to handle Tasmanian tiger and dodo de-extinction pipelinespre #5 · pending · 2027-06-16 — First viable woolly mammoth embryo announcement (Asian elephant surrogate)pre #4 · pending · 2029-12-31 — First live-born woolly mammoth calf (or formal program failure announcement)pre #3 · pending · 2031-02-03 — Q1 window check-in (25%)pre #2 · pending · 2031-03-08 — Q2 window check-in (50%)pre #1 · pending · 2031-04-10 — Q3 window check-in (75%)pre #6 · pending · 2028-12-29 — 100GW+ frontier AI training campus operationalpre #5 · pending · 2028-12-31 — AI-driven cancer breakthrough: novel mechanism or candidate published in Nature/NEJM/Cellpre #4 · pending · 2029-03-31 — Healthy human lifespan-extension intervention enters Phase II/III at scalepre #3 · pending · 2029-12-21 — Q2 window check-in (50%)pre #2 · pending · 2029-12-31 — 'Country of geniuses' framing adopted in mainstream economic forecasts and government strategy docspre #1 · pending · 2031-12-16 — Q3 window check-in (75%)pre #6 · pending · 2031-12-27 — Q1 window check-in (25%)pre #5 · pending · 2032-01-01 — Drug discovery cycle time benchmark drops from ~10 years to under 4 years for AI-led programs (industry-wide median)pre #4 · pending · 2033-12-22 — Q2 window check-in (50%)pre #3 · pending · 2034-07-02 — First synthetic organ (lab-grown, AI-designed) successfully transplanted into human in approved clinical trialpre #2 · pending · 2035-12-18 — Q3 window check-in (75%)pre #1 · pending · 2036-03-31 — Cascade: WHO or major health body announces global cumulative >50% reduction in mortality from previously-fatal cancerspre #6 · hit · 2025-08-15 — Varda Series C ($187M) closes — capital for commercial scalepre #5 · overdue · 2026-02-19 — Q1 window check-in (25%)pre #4 · overdue · 2026-04-10 — Q2 window check-in (50%)pre #3 · hit · 2026-04-30 — Varda W-4 mission in orbit; W-5 expected before end of yearpre #2 · overdue · 2026-05-29 — Q3 window check-in (75%)pre #1 · pending · 2026-07-01 — Varda begins biologics (monoclonal antibody) crystallization programcascade #1 · pending · 2026-07-31 — First commercial pharma drug returned from microgravity demonstrably superiorcascade #2 · pending · 2027-05-02 — FDA / partner announces clinical pathway for orbital-manufactured pharmapre #6 · hit · 2026-01-12 — NVIDIA + Eli Lilly announce $1B AI co-innovation lab on BioNeMo platformpre #5 · hit · 2026-03-16 — Roche launches NVIDIA-powered AI factory for therapeutics developmentpre #4 · pending · 2026-12-15 — ≥200 AI-discovered drug programs in clinical developmentpre #3 · pending · 2027-01-22 — Q2 window check-in (50%)pre #2 · pending · 2027-12-16 — First BioNeMo / Evo 2-designed therapeutic enters Phase 1 human trialpre #1 · pending · 2028-02-01 — Q3 window check-in (75%)cascade #1 · pending · 2029-03-31 — ≥1 BioNeMo-designed drug receives FDA breakthrough/fast-track designationpre #6 · pending · 2026-12-12 — Q1 window check-in (25%)pre #5 · pending · 2027-09-16 — Rentosertib or other AI-designed drug reads out positive Phase III resultpre #4 · pending · 2027-11-22 — Q2 window check-in (50%)pre #3 · pending · 2028-01-30 — Biotech sector forward P/E or median EV/Revenue rerates above 5y average per XBI/Bloombergpre #2 · pending · 2028-07-01 — Gene-editing TAM expansion: first cardiovascular-prevention gene therapy enters Phase IIIpre #1 · pending · 2028-11-01 — Q3 window check-in (75%)pre #6 · pending · 2032-12-01 — Q1 window check-in (25%)pre #5 · pending · 2036-07-01 — First in-human BCI demonstrates bidirectional brain-to-brain signal transmissionpre #4 · pending · 2036-11-01 — Q2 window check-in (50%)pre #3 · pending · 2037-12-31 — Global average life expectancy posts first single-year gain of >0.8 years attributable to medical breakthroughspre #2 · pending · 2040-10-02 — Q3 window check-in (75%)pre #1 · pending · 2040-12-31 — Scenario fires: ASI slow: post-2040 / soft takeoffpre #6 · pending · 2030-07-02 — Longevity escape velocity reachable for diligent/informed individuals (Kurzweil 'Bridge 2' threshold)pre #5 · pending · 2031-08-23 — Q1 window check-in (25%)pre #4 · pending · 2032-03-31 — First in-human medical nanorobot trial cleared by FDA or comparable regulatorpre #3 · pending · 2033-04-14 — Q2 window check-in (50%)pre #2 · pending · 2034-12-05 — Q3 window check-in (75%)pre #1 · pending · 2034-12-31 — WHO declares one major age-related disease (Alzheimer's or one cancer subtype) effectively eliminated as cause of death cascade #1 · pending · 2037-07-02 — Average OECD life expectancy at birth crosses 90 yearscascade #2 · pending · 2037-12-31 — First brain-to-brain or whole-brain emulation demonstration peer-reviewedpre #6 · pending · 2027-12-18 — Q1 window check-in (25%)pre #5 · pending · 2029-03-31 — Drug-discovery preclinical-to-IND timeline drops below 18 months at industrial scalepre #4 · pending · 2029-12-04 — Q2 window check-in (50%)pre #3 · pending · 2030-06-30 — First AI-designed therapeutic receives FDA approvalpre #2 · pending · 2031-11-20 — Q3 window check-in (75%)pre #1 · pending · 2033-09-30 — Major disease (specific cancer subtype, monogenic disorder) declared 'effectively eradicated' due to AI-designed therapypre #3 · pending · 2027-08-21 — Q1 window check-in (25%)pre #2 · pending · 2029-04-10 — Q2 window check-in (50%)pre #1 · pending · 2030-11-29 — Q3 window check-in (75%)pre #6 · pending · 2027-05-02 — Major seed company (Corteva/Bayer/Syngenta) announces drone+robot phenotyping integrated into trait pipelinepre #5 · pending · 2028-01-01 — Bayesian-optimization + agentic-AI trait discovery published as commercial breeding-cycle acceleratorpre #4 · pending · 2028-03-16 — Commercial deployment of TerraSentia-class field-phenotyping robot fleet exceeds 1000 unitspre #3 · pending · 2028-05-24 — Q2 window check-in (50%)pre #2 · pending · 2029-07-01 — First climate-resilient cultivar commercialized with HTP-driven trait identification creditedpre #1 · pending · 2029-08-04 — Q3 window check-in (75%)target window end · today (amber dashed) · ✓/✗/◐ history strip = past resolutions · ghost arrows = evidence shift
88 plotted · click any dot for detail

Top movers

Predictions where past + recent evidence has shifted current_prob most off the analyst-seeded prior.

Legend

Color = domain · purple ring = scenario · red ring = thesis killer · green ↑ / red ↓ ghost arrows = evidence shift > 10pp · ribbon dots = milestone chain (left = leading signals, right = cascades)
AILabor/JobsMacro/EconomyBiotech/LongevityAuto/TransportRoboticsMarkets/StocksSpaceEnergyGeopoliticsEducationCryptoSemisDefenseConsumerQuantum
Y-axis bands: 0–25 % red-tint (unlikely) · 25–75 % amber (uncertain) · 75–100 % green-tint (likely). Vertical amber dashed line = today. Each prediction sits at (its expected resolution date, its current probability). Probabilities are conditional on everything that has already happened — past hits/misses + recent intake updates feed into the LBP propagation that produced these values.