Kitrid disease is the leading extinction driver in frogs/amphibians and can be solved with genetic engineering

Kitrid disease is the leading extinction driver in frogs/amphibians and can be solved with genetic engineering | It's the leading extinction driver right now on the planet in frogs and and and amphibians... it's something that we can solve with genetic engineering

It's the leading extinction driver right now on the planet in frogs and and and amphibians... it's something that we can solve with genetic engineering

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Adverse (5)

{
  "nia": false,
  "url": "https://www.youtube.com/watch?v=Goa6c6Qz__I",
  "mode": "PREDICTION",
  "role": "Guest-CEO",
  "context": "It's the leading extinction driver right now on the planet in frogs and and and amphibians... it's something that we can solve with genetic engineering, right? And so for us, uh you know, and not only can we solve the current problem, but we can also create kit frogs and salamanders and others in in and that are kitrred resistance",
  "verbatim": "It's the leading extinction driver right now on the planet in frogs and and and amphibians... it's something that we can solve with genetic engineering",
  "conv_cues": "can solve; we can also create",
  "direction": "HAPPEN",
  "timeframe": "Future",
  "conv_level": "HIGH",
  "milestones": [
    {
      "kind": "quartile_checkpoint",
      "label": "Q1 window check-in (25%)",
      "status": "pending",
      "weight": 0.05,
      "ordinal": -7,
      "source_id": null,
      "expected_date": "2027-03-07",
      "observed_date": null
    },
    {
      "kind": "llm_pre_event",
      "label": "First successful CRISPR-engineered chytrid-resistant frog line published in peer-reviewed journal",
      "source": "https://www.amphibians.org/news/chytrid-fighting-genes-to-save-species-on-the-brink/",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -6,
      "source_id": null,
      "confidence": 0.6,
      "expected_date": "2027-09-16",
      "research_origin": "training",
      "expected_date_range": {
        "to": "2028-12-31",
        "from": "2026-06-01"
      },
      "measurement_criterion": "Nature/Science/PNAS or Cell paper documents heritable Bd-resistance gene insertion in any amphibian species via CRISPR-Cas9, e.g., from JCU Queensland or Colossal Foundation programs"
    },
    {
      "kind": "quartile_checkpoint",
      "label": "Q2 window check-in (50%)",
      "status": "pending",
      "weight": 0.05,
      "ordinal": -5,
      "source_id": null,
      "expected_date": "2028-01-12",
      "observed_date": null
    },
    {
      "kind": "llm_pre_event",
      "label": "Colossal Foundation or partner publishes Bd-resistance gene multiplex editing protocol in great spotted tree frog or corroboree frog",
      "source": "https://colossalfoundation.org/project/saving-amphibians-from-chytrid-fungus/",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -4,
      "source_id": null,
      "confidence": 0.55,
      "expected_date": "2028-03-31",
      "research_origin": "training",
      "expected_date_range": {
        "to": "2029-06-30",
        "from": "2027-01-01"
      },
      "measurement_criterion": "Colossal Biosciences/Foundation press release or peer-reviewed publication describes multiplex CRISPR transgene producing chytrid-specific antibodies in named critically endangered species"
    },
    {
      "kind": "quartile_checkpoint",
      "label": "Q3 window check-in (75%)",
      "status": "pending",
      "weight": 0.05,
      "ordinal": -3,
      "source_id": null,
      "expected_date": "2028-11-18",
      "observed_date": null
    },
    {
      "kind": "llm_post_event",
      "label": "First field release of gene-edited chytrid-resistant amphibian population approved by national wildlife regulator",
      "source": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12881173/",
      "status": "pending",
      "weight": 0.4,
      "ordinal": -2,
      "source_id": null,
      "confidence": 0.4,
      "expected_date": "2029-03-31",
      "research_origin": "training",
      "expected_date_range": {
        "to": "2030-06-30",
        "from": "2028-01-01"
      },
      "measurement_criterion": "Australian DCCEEW, US FWS, or equivalent national authority issues permit for controlled release of CRISPR-edited frogs into native range"
    },
    {
      "kind": "llm_post_event",
      "label": "IUCN Red List downlists at least one chytrid-affected species citing genetic-rescue intervention",
      "source": "https://w
... (truncated)