0 25 50 75 100 history 230_014 resolved hit on 2026-04-29 — The consulting industry will go through the roof as consultants leverage AI to automate/improve exis ✓ 238_010 resolved hit on 2026-04-29 — AI takeoff/inflection is happening now ✓ 240_027 resolved hit on 2026-04-29 — SpaceX and xAI will merge and go public in the next couple of months ✓ AI_023 resolved hit on 2026-04-29 — Inside Uber, 90% of software engineers currently rely on AI, and executive teams rehearse high-stake ✓ 238_009 resolved hit on 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) ✓ CMQ_027 resolved hit on 2026-04-29 — The inference inflection has arrived — industry transitioning from training-dominated capex (2023-20 ✓ AI_005 resolved hit on 2026-04-29 — Current frontier models suffer from 'jagged intelligence' — excelling at international mathematics o ✓ 240_001 resolved hit on 2026-04-29 — NVIDIA to reach at least $1 trillion in bookings/revenue through 2027 ✓ FUT_024 resolved hit on 2026-04-29 — XPT 2022 tournament assigned mere 2.3% probability to AI achieving gold-medal performance in Interna ✓ AUT_003 resolved hit on 2026-04-29 — 'Vibe coding' — the full delegation of syntactic code generation to autonomous models, with human en ✓ 242_057 resolved hit on 2026-04-30 — Artemis 2 launches April 1, 2026 - circumlunar mission ✓ 244_019 resolved hit on 2026-04-29 — Peter's son won't need a driver's license in 2 years ✓ 241_004 resolved hit on 2026-04-29 — AI progress is not stoppable or controllable by any government, individual, or corporation ✓ 229_047 resolved hit on 2026-04-29 — Figure's 3,000 B200 GPU cluster is coming online for Helix pre-training with much larger GPUs planne ✓ IND_021 resolved hit on 2026-04-29 — February 2026 realized forecast: AI automation capabilities necessitated severe operational restruct ✓ SEM_048 resolved hit on 2026-04-30 — OpenAI restructured into a $500 billion colossus by removing profit caps for investors (to support S ✓ SPC_008 resolved hit on 2026-04-29 — SpaceX milestone-delivery statistics: 16% on-time, 31% late, 53% undelivered overall — planetary mil ✓ SPC_025 resolved hit on 2026-04-29 — Critical misalignment in the AI industry: approximately 300 AI capabilities researchers for every on ✓ 232_021 resolved hit on 2026-04-29 — No chance AI will be paused in the next three years given current administration and China competiti ✓ 241_006 resolved hit on 2026-04-29 — Everyone is out of hardware and electricity due to AI boom ✓ AUT_019 resolved hit on 2026-04-29 — Weil's April 2026 exit from OpenAI VP of Science signals critical juncture — as AI transitions from ✓ 234_012 resolved hit on 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 ✓ 242_015 resolved hit on 2026-04-29 — Full autonomy achieved within 2 years before Salim's son gets driver's license ✓ 233_020 resolved hit on 2026-04-29 — Texas Sports Academy will operate at $300/month per parent using Texas billion-dollar voucher progra ✓ CMQ_043 resolved hit on 2026-04-29 — In complex Agentic AI workloads, CPU-side processing accounts for 50-90% of end-to-end latency — val ✓ 246_038 resolved hit on 2026-04-29 — Data centers are driving frontier labs into space (orbital data centers). ✓ 238_041 resolved hit on 2026-04-29 — Apple will eventually integrate highly competent private frontier models into its OS (when not if) ✓ 247_042 resolved hit on 2026-04-29 — Professional Robotics League first US match on April 19, 2026 in Boston ✓ AUT_017 resolved hit on 2026-04-29 — Defining 2023-2026 shift: maturation of 'Agentic AI' via heavy fine-tuning of pre-trained LLMs using ✓ IND_013 resolved hit on 2026-04-29 — General intelligence requires systems capable of solving tasks across multidimensional continuous do ✓ AI_016 resolved hit on 2026-04-29 — The 'cost of intelligence' collapse has officially superseded traditional Moore's Law dynamics — an ✓ CMQ_053 resolved hit on 2026-04-30 — Figure AI secured $675M Series B in 2024 and partnered commercially with BMW — addressing skilled-la ✓ AI_010 resolved hit on 2026-04-29 — The 2026 development landscape has entered the 'Slopacolypse' — AI writes the vast majority of new c ✓ CYB_018 resolved hit on 2026-04-29 — Figure AI valuation has eclipsed $39 billion by early 2026 — surpassing SpaceX's 2020 valuation — ba ✓ 247_058 resolved hit on 2026-04-29 — Jury selection begins April 27, 2026 for Musk v OpenAI trial ✓ 235_002 resolved hit on 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026). ✓ 245_012 resolved hit on 2026-04-29 — UAE's Biovault is a nine-figure initiative for both Colossal and the UAE ✓ CYB_026 resolved hit on 2026-04-29 — The initial assumption that the United States can maintain a durable long-term 'moat' based purely o ✓ 246_047 resolved hit on 2026-04-29 — Anthropic ARR reached $30B, surpassing OpenAI's $24-25B. ✓ FUT_003 resolved hit on 2026-04-29 — Superforecaster consensus assigns 0.38% probability to AI-driven human extinction by 2100 vs domain- ✓ ROB_006 resolved hit on 2026-04-29 — 'English is the hottest new programming language' — natural language becomes the dominant programmin ✓ ROB_012 resolved hit on 2026-04-29 — The ultimate bottleneck for global robotics deployment is NOT software architecture but physical GPU ✓ INF_019 resolved hit on 2026-04-29 — A modern hyperscale AI data center can consume up to 5 million gallons of freshwater per day for eva ✓ INF_033 resolved hit on 2026-04-29 — Technology conglomerates have mobilized unprecedented political capital to ensure AI-friendly regula ✓ SEM_039 resolved hit on 2026-04-29 — Block unveiled proprietary Bitcoin mining ASIC at 709 Terahashes/second (TH/s) — leading indicator f ✓ SEM_042 resolved hit on 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. ✓ INF_039 resolved hit on 2026-04-29 — Consumer-facing AI hardware shortages will worsen: high-Unified-Memory Apple Mac Studio lead times n ✓ 229_013 resolved hit on 2026-04-29 — The next 12-18 months will be the largest AI transformation ever seen. ✓ 248_040 resolved hit on 2026-04-29 — Pausing AI will fail and only accelerate race dynamics. ✓ 248_005 resolved hit on 2026-04-29 — V3 Starlink satellites will deliver over 1 TB/s downlink and 200+ Gbps uplink each. ✓ ROB_016 resolved hit on 2026-04-29 — Block executed massive layoffs explicitly reframing the company as a 'smaller, faster, intelligence- ✓ CMQ_038 resolved hit on 2026-12-31 — Micron has initiated HVM production of HBM4 36GB module delivering 2.8 TB/s bandwidth — optimized to ✓ 235_038 resolved hit on 2026-04-29 — David Sinclair begins partial epigenetic reprogramming trials with Life Biosciences in March 2026. ✓ SEM_011 resolved hit on 2026-04-30 — Nvidia became the world's first $5 trillion company (late 2025), operating a near-monopoly on advanc ✓ SEM_014 resolved hit on 2026-04-30 — Nvidia's Arizona-based TSMC factory successfully fabricated cutting-edge semiconductors on US soil f ✓ 237_028 resolved hit on 2026-04-29 — Abundance Summit will live-stream Eric Schmidt, Uber CEO Dara Khosrowshahi, and a WTF Moonshot podca ✓ 238_072 resolved hit on 2026-04-29 — Small-to-large model scaling time has collapsed from 6-12 months to 6 days ✓ 232_014 resolved hit on 2026-04-29 — Recursive self-improvement is already here, not 12 months away. ✓ 241_052 resolved hit on 2026-04-29 — Standard AI data centers being built at 400 MW scale, half-mile long ✓ 245_025 resolved hit on 2026-04-29 — Colossal gene editing efficiency has risen from 15% industry / 40% internal to 90% at hundreds of ed ✓ SPC_014 resolved hit on 2026-04-29 — Starlink constitutes 65% of all active satellites globally by 2026 — making LEO operational manageme ✓ 248_003 resolved hit on 2026-04-29 — SpaceX plans to launch 40,000 V3 Starlink satellites and then 120,000 V4 satellites. ✓ SPC_031 resolved hit on 2026-04-29 — SpaceX's reusability program has driven the cost per kilogram to Low Earth Orbit from $15,600 in 200 ✓ 229_028 resolved hit on 2026-04-29 — Figure will NOT license out its neural net or hardware IP to third-party form-factor builders. ✓ CYB_015 resolved hit on 2026-04-29 — The human hiring process becomes progressively distorted as autonomous bot agents actively screen re ✓ CYB_009 resolved hit on 2026-04-29 — Hardware-software alignment will force widespread foundational-codebase rewrites — exemplified by Mi ✓ CYB_029 resolved hit on 2026-04-29 — Corporate API providers will increasingly restrict third-party agent harnesses (exemplified by Anthr ✓ SEM_029 resolved hit on 2026-04-29 — Blackwell RTX PRO 5000 (72GB) engineered with 50% memory boost over previous generation — deliberate ✓ INF_049 resolved hit on 2026-04-29 — Modern AI data centers are no longer server farms but "gigawatt factories"; energy — not silicon sup ✓ INF_065 resolved hit on 2026-04-29 — Uber has committed an initial $100 million specifically to develop EV charging infrastructure tailor ✓ SEM_008 resolved hit on 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. ✓ SEM_012 resolved hit on 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying ✓ SEM_027 resolved hit on 2026-04-29 — Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap ✓ SPC_004 resolved hit on 2026-04-29 — Rocket Lab USA (RKLB) will leverage its dominance in the small-to-medium launch market — 2025 revenu ✓ SPC_006 resolved hit on 2026-04-29 — Starlink exceeded 10 million active global subscribers by February 2026, generating estimated annual ✓ 231_002 resolved miss on 2026-04-29 — Grok 5 launches in March with massive expansion in training set, parameters, and capability. ✗ 231_018 resolved miss on 2026-04-29 — Blitz will switch to next generation model in late March 2026. ✗ 235_008 resolved miss on 2026-04-29 — Anthropic/OpenAI will be forced to release first-party OpenClaw competitor in next couple months. ✗ 244_020 resolved partial on 2026-05-01 — Need for driver's licenses is going to collapse over the next few years ◐ 239_033 resolved partial on 2026-05-21 — Optimus 3 will be by far the most advanced robot in the world ◐ INF_058 resolved partial on 2026-05-01 — The electrical grid topology will transition from centralized to highly decentralized: localized sol ◐ 232_003 resolved partial on 2026-05-10 — AI will make workers 3x more productive, effectively reducing headcount by two-thirds unless compani ◐ 236_033 resolved partial on 2026-05-17 — Pie will grow very quickly as AI does work of millions of humans in hours ◐ SEM_041 resolved partial on 2026-05-17 — At least 100,000 personal AI robots will be preordered in 2025 (driven by speech/vision/dexterity ad ◐ AI_028 resolved partial on 2026-05-01 — Decentralized offline messaging via Bluetooth Low Energy (BLE) mesh networks — exemplified by Dorsey ◐ 238_020 resolved partial on 2026-05-01 — Math field is 'cooked' — AI will solve research-level mathematics (first open hard math problem immi ◐ 231_031 resolved partial on 2026-05-10 — OpenAI planning $100B infrastructure spend, going public this year at $1T valuation. ◐ CMQ_036 resolved partial on 2026-12-31 — SK Hynix will maintain industry HBM lead, capturing >50% of NVIDIA's total HBM procurement (HBM3E + ◐ 246_001 resolved partial on 2026-09-30 — SpaceX will IPO at $2 trillion valuation, raising $75 billion as largest IPO in history. ◐ AI_021 resolved partial on 2026-05-03 — The 2026-2027 window is the 'Great Disemboweling' of white-collar employment — millions of mid-caree ◐ 246_008 resolved partial on 2026-05-01 — Elon Musk will merge SpaceX and XAI (with Tesla) within a year (Peter's view). ◐ 247_023 resolved partial on 2026-05-17 — AI will be able to do everything a white collar worker does imminently ◐ 245_008 resolved partial on 2026-05-24 — More direwolves will be produced after initial Romulus and Remus ◐ INF_005 resolved partial on 2026-05-01 — Skilled trade labor (welders, HVAC, electricians, plumbers, heavy-equipment operators, network techn ◐ INF_029 resolved partial on 2026-05-03 — Enterprise AI will shift the software economy from licensing to 'outcome-based economics' — corporat ◐ 246_005 resolved partial on 2026-05-10 — OpenAI and Anthropic IPOs will head toward $1 trillion valuations. ◐ INF_036 resolved partial on 2026-05-01 — AI will develop a 'kinetic' edge where capital assets (drones, autonomous vehicles, agricultural rob ◐ SEM_049 resolved partial on 2026-05-24 — AI will soon fully automate software engineering, achieving massive cost reductions via iterative se ◐ ROB_002 resolved partial on 2025-12-31 — 99% of code generation will be entirely automated by the end of 2025 — the elimination of the primar ◐ INF_004 resolved partial on 2026-05-17 — China has massive latent 'ghost data center' capacity — fully powered facilities sitting empty await ◐ SEM_033 resolved partial on 2026-05-10 — AI is gaining the capability to autonomously conduct original physics research (e.g., GPT-5.2 Pro pr ◐ INF_060 resolved partial on 2026-05-10 — Three new battery chemistries beyond lithium-ion will commercialize in 2026 — signaling a definitive ◐ SEM_002 resolved partial on 2026-05-21 — By 2025-2026, AI model outputs will outpace the cognitive capabilities of college graduates (driven ◐ SEM_022 resolved partial on 2026-05-01 — FP4 / ternary-weight architectures decouple AI capability from raw transistor density — embargoed na ◐ SEM_021 resolved partial on 2026-05-10 — Largest AI models will see a 100x leap in size by 2026, driven largely by Chinese research efforts u ◐ SEM_037 resolved partial on 2026-05-17 — For any job you can do on the other side of a screen, AI will probably be able to do it better, fast ◐ SEM_040 resolved partial on 2026-05-03 — Bitcoin treasury/business strategy allows companies to outpace rival enterprise software firms by 10 ◐ SEM_045 resolved partial on 2026-05-03 — Traditional corporate structures will move rapidly toward AI-native operating models by 2026 — forci ◐ CYB_003 resolved partial on 2026-05-17 — Localized, ungoverned multi-agent networks will spontaneously generate their own social networks, go ◐ INF_008 resolved partial on 2026-05-01 — Leading AI model intelligence has been improving by roughly 2.5 IQ points per month since May 2024 — ◐ INF_031 resolved partial on 2028-10-31 — The biggest near-term AI risk to humanity is AI companies themselves acting without proper oversight ◐ INF_030 resolved partial on 2026-05-01 — By 2026, generative AI will democratize analytical and operational capabilities previously exclusive ◐ SEM_006 resolved partial on 2025-12-31 — OpenAI will operate at a ~$9B deficit in 2025, driven almost entirely by advanced-chip acquisition a ◐ Jan 2026 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2027 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2028 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2029 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2030 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2031 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2032 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2033 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2034 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2035 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2036 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2037 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2038 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2039 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2040 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2041 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2042 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2043 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2044 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2045 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Jan 2046 Feb Mar Apr May Jun today pre #6 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026). pre #5 · pending · 2027-09-16 — ATP-BIO consortium or NIH funds >=$50M dedicated organ-banking initiative pre #4 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump ad pre #3 · pending · 2028-07-01 — Reversibly cryopreserved mammalian organ successfully transplanted into recipient pre #2 · pending · 2028-09-30 — 21st Century Medicine or competitor publishes large-mammal whole-brain reversible vitrification pre #1 · pending · 2029-03-31 — FDA opens pre-IND track for vitrified-organ transplant trial cascade #1 · pending · 2032-07-01 — First UNOS-listed transplant using cryopreserved organ cascade #2 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve e cascade #6 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #2 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026). pre #1 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. cascade #1 · pending · 2030-04-18 — Dario Amodei will solve most/all neurological diseases by end of decade cascade #2 · pending · 2030-10-10 — Europa Clipper will arrive at Jupiter in 2030, conducting 50 passes near Europa. cascade #3 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #4 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve e pre #6 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #5 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026). pre #4 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump ad pre #3 · pending · 2028-12-31 — AI healthcare reduces all-cause mortality in any large-scale deployment pre #2 · pending · 2029-07-01 — AI sudden-cardiac-death detection deployed at population scale pre #1 · pending · 2031-10-01 — Global daily mortality decreases despite population growth cascade #1 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #2 · pending · 2036-08-14 — People will be on Mars within 10 years cascade #3 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #4 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow. cascade #5 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 pre #6 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #5 · pending · 2026-06-25 — Nvidia agreed to remit 15% of China chip-sale revenue directly to US government in exchange for reversing specific AI ch pre #4 · pending · 2027-05-02 — Neuralink human trial enrollment exceeds 50 participants pre #3 · pending · 2030-07-02 — FDA grants first non-medical / cognitive-augmentation BCI trial approval pre #2 · pending · 2032-01-01 — First FDA full-market approval (non-IDE) for any consumer-targeted invasive BCI pre #1 · pending · 2032-12-31 — Pediatric BCI trial (under 18) approval by FDA or equivalent regulator cascade #1 · pending · 2035-06-16 — Cumulative invasive BCI implant population exceeds 100,000 globally cascade #2 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 cascade #3 · pending · 2046-07-24 — Combustion engines largely gone in 20 years but world will be very different cascade #4 · pending · 2048-08-06 — Humans will be demonstrably less safe than autonomous drivers (within 25 years, not 15) cascade #5 · pending · 2063-06-17 — Under a certain age (40-50) life expectancy is infinity due to longevity escape velocity. cascade #6 · pending · 2063-06-21 — Peter's 14-year-old son Milan will never get a driver's license. pre #6 · hit · 2026-02-19 — VITARI pre-orders open H1 2026 pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2026-09-30 — First VITARI commercial shipment in H2 2026 cascade #2 · pending · 2026-12-15 — Independent customer benchmarks confirm $100/genome at >=Q30 90% cascade #3 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #4 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. cascade #5 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #6 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. pre #6 · pending · 2027-04-18 — Q1 window check-in (25%) pre #5 · pending · 2027-11-01 — State-level lab-grown meat bans repealed or struck down pre #4 · pending · 2028-03-31 — Cultivated meat production cost falls below $20/lb wholesale pre #3 · pending · 2028-04-06 — Q2 window check-in (50%) pre #2 · pending · 2029-03-26 — Q3 window check-in (75%) pre #1 · pending · 2029-09-15 — Cultivated meat captures >1% of US ground meat retail dollars pre #6 · pending · 2028-12-31 — AI-designed aging-reversal compound enters human trial pre #5 · pending · 2029-03-31 — Scenario fires: AGI mid: Kurzweil 2029 path pre #4 · pending · 2029-12-31 — Annual healthy-LE gain crosses 0.5 year per calendar year pre #3 · pending · 2030-07-02 — First demonstrated whole-organ regeneration in human trial pre #2 · pending · 2031-05-17 — Biological-age reversal demonstrated in healthy-cohort RCT pre #1 · pending · 2033-05-16 — Healthy life-expectancy reaches 1.0 year per calendar year (LEV operational) cascade #1 · pending · 2036-08-14 — People will be on Mars within 10 years cascade #2 · pending · 2036-08-24 — Mass driver on the moon within 10 years cascade #3 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #4 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow. pre #6 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #5 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #4 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026). pre #3 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #2 · pending · 2028-03-16 — Mouse whole-brain connectome project funded at >$500M pre #1 · pending · 2032-07-01 — First whole-mouse-brain connectome publication cascade #1 · pending · 2033-12-15 — First running mouse whole-brain emulation cascade #2 · pending · 2036-07-30 — Human plumbers are safe for at least 10 years and probably significantly longer cascade #3 · pending · 2036-08-14 — People will be on Mars within 10 years cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #5 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow. cascade #6 · pending · 2040-07-01 — First whole-human-brain connectome released pre #5 · hit · 2026-03-15 — Eon Systems demonstrates whole-fly multi-behavior emulation pre #4 · overdue · 2026-05-29 — Q1 window check-in (25%) pre #3 · pending · 2026-06-28 — Q2 window check-in (50%) pre #2 · pending · 2026-07-01 — Eon publishes Nature/bioRxiv paper on fly-brain emulation pre #1 · pending · 2026-07-28 — Q3 window check-in (75%) cascade #1 · pending · 2026-08-31 — Eon announces mouse-brain connectome target with timeline cascade #2 · pending · 2026-12-15 — Mouse connectome generation funding round announced cascade #3 · pending · 2028-09-15 — First mouse brain region (e.g., visual cortex) emulated end-to-end pre #6 · hit · 2026-03-16 — First multi-behavior cyber-Drosophila body-brain integration (March 2026) pre #5 · pending · 2027-05-04 — Q1 window check-in (25%) pre #4 · pending · 2028-05-08 — Q2 window check-in (50%) pre #3 · pending · 2029-03-16 — Eon publishes mouse-brain partial emulation (~70M neurons) pre #2 · pending · 2029-05-13 — Q3 window check-in (75%) pre #1 · pending · 2029-07-01 — First peer-reviewed human cortical organoid + connectome integration cascade #1 · pending · 2030-07-02 — First publicly announced commercial 'whole-brain digital twin' service pre #6 · pending · 2026-12-31 — Healthcare humanoid robot market size hits $2.96B in 2026 pre #5 · pending · 2026-12-31 — Robotic-assisted surgery market crosses $14B globally pre #4 · pending · 2027-03-17 — AI diagnostic systems (Aidoc, Viz.ai) integrated in >50% of US hospitals pre #3 · pending · 2027-03-19 — Q2 window check-in (50%) pre #2 · pending · 2027-08-28 — Q3 window check-in (75%) pre #1 · pending · 2027-12-16 — Optimus / humanoid surgery demonstration on cadaver or live procedure cascade #1 · pending · 2028-11-30 — Universal access to AI-doctor better than richest-person care NOT achieved by 2028-11-30 pre #6 · pending · 2027-10-01 — Q2 window check-in (50%) pre #5 · pending · 2028-01-01 — FDA clearance of AI-as-medical-device for back pain triage or treatment pre #4 · pending · 2028-04-30 — Major payer covers AI-driven back-pain therapy pre #3 · pending · 2028-06-17 — Q3 window check-in (75%) pre #2 · pending · 2028-08-30 — Neuralink or competitor BCI receives FDA approval for chronic-pain indication pre #1 · pending · 2029-03-01 — Population-scale outcomes evidence: AI back-pain interventions show >30% improvement vs SOC pre #6 · hit · 2026-04-29 — Anthropic will exceed OpenAI in revenue this year (2026). pre #5 · pending · 2026-12-15 — Isomorphic Labs pipeline expands to 17+ active programs with Eli Lilly and Novartis partnerships in mid-trials pre #4 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump ad pre #3 · pending · 2029-09-15 — First AI-designed drug receives FDA approval (any indication, primary structure designed by frontier model) pre #2 · pending · 2030-04-01 — First 'virtual cell' (full molecular-state predictive simulation) demonstrated for clinical-grade intervention modeling pre #1 · pending · 2031-03-17 — Cumulative AI-designed drug approvals reach 10+ across major disease categories cascade #1 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #2 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #3 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #4 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve e cascade #5 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 pre #6 · hit · 2026-04-29 — Nvidia became the world's first $5 trillion company (late 2025), operating a near-monopoly on advanced AI chips. pre #5 · hit · 2026-04-29 — Nvidia Data Center revenue +66% YoY, contributing ~90% of $57B fiscal Q3 revenue; >$4.5T market cap entirely underpinned pre #4 · hit · 2026-04-29 — Nvidia's Arizona-based TSMC factory successfully fabricated cutting-edge semiconductors on US soil for first time in dec pre #3 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #2 · pending · 2026-06-25 — Nvidia agreed to remit 15% of China chip-sale revenue directly to US government in exchange for reversing specific AI ch pre #1 · pending · 2028-01-01 — First FDA pivotal approval where Phase 3 control arm is fully replaced by digital twin cascade #1 · pending · 2030-05-17 — First sub-indication approved with zero traditional clinical trials (computational + Bayesian only) cascade #2 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #3 · pending · 2036-03-23 — World will have 10x more wealth around 2034-2036 cascade #4 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 cascade #5 · pending · 2063-06-17 — Under a certain age (40-50) life expectancy is infinity due to longevity escape velocity. cascade #6 · pending · 2063-06-21 — Peter's 14-year-old son Milan will never get a driver's license. pre #3 · pending · 2027-12-24 — Q1 window check-in (25%) pre #2 · pending · 2029-08-19 — Q2 window check-in (50%) pre #1 · pending · 2031-04-14 — Q3 window check-in (75%) pre #2 · hit · 2025-01-30 — Khaleesi (third direwolf, female) birth announcement pre #1 · hit · 2025-10-01 — Direwolf pack social-development milestone (1-year birthday update) cascade #1 · hit · 2026-04-30 — Colossal announces new de-extinct species (bluebuck or other) cascade #2 · pending · 2026-12-15 — Colossal announces additional direwolves (4th-onwards) cascade #3 · pending · 2028-03-16 — Woolly mammoth first birth (2028 target tracking) pre #6 · hit · 2026-02-12 — Engineered PETase enzyme paper (Bhattacharya et al.) published in FEBS Journal — highly active polyester degradation pre #5 · pending · 2026-07-20 — Q1 window check-in (25%) pre #4 · pending · 2026-10-10 — Q2 window check-in (50%) pre #3 · pending · 2026-12-15 — PETase/MHETase variant with gut-compatible pH/temperature window (pH 1-7, 37C) demonstrated pre #2 · pending · 2026-12-31 — Q3 window check-in (75%) pre #1 · pending · 2027-03-17 — First published in-vivo (animal model) study of orally-delivered plastic-degrading enzyme on microplastic absorption cascade #1 · pending · 2027-05-17 — Supplement company / startup announces clinical work toward microplastic-degrading oral product pre #6 · pending · 2027-06-29 — Q2 window check-in (50%) pre #5 · pending · 2027-06-30 — Breaking publishes preclinical paper or whitepaper on human-body microplastic supplement pre #4 · pending · 2027-09-30 — Breaking environmental product (plastic-degrading microbe) hits commercial scale milestone pre #3 · pending · 2028-01-13 — First peer-reviewed human RCT data on a microplastic-clearance intervention pre #2 · pending · 2028-01-27 — Q3 window check-in (75%) pre #1 · pending · 2028-03-31 — Breaking launches DTC supplement product or files IND with FDA pre #6 · pending · 2026-11-15 — Colossal mammoth embryos ready for elephant surrogate implantation by end of 2026 pre #5 · pending · 2027-05-02 — EXTEND artificial womb begins first-in-human clinical trials for premature infants pre #4 · pending · 2027-06-07 — Q1 window check-in (25%) pre #3 · pending · 2028-07-01 — First woolly mammoth calf born from edited Asian elephant surrogate pre #2 · pending · 2028-07-15 — Q2 window check-in (50%) pre #1 · pending · 2029-08-23 — Q3 window check-in (75%) cascade #1 · pending · 2030-10-01 — Productionized de-extinction species via artificial wombs (event) pre #6 · overdue · 2026-04-12 — Colossal's 'Lamm $5.4T invasive-species' narrative is repeatedly cited by analysts pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2026-12-15 — Colossal-affiliated Tropic Biosciences reports disease-resistant crop deployment cascade #2 · pending · 2026-12-15 — Industry analyst sizes the disease-resistant ag-biotech market explicitly cascade #3 · pending · 2027-03-17 — Colossal Foundation EEHV mRNA vaccine expands to additional zoos/herds cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #5 · pending · 2027-10-01 — First publicly traded comp pure-play in disease-resistant biotech announces revenue cascade #6 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. pre #6 · pending · 2026-12-14 — Q1 window check-in (25%) pre #5 · pending · 2026-12-15 — Gene drive screwworm efficiency demonstrated in lab pre #4 · pending · 2026-12-31 — USDA south Texas sterile fly facility operational (100M flies/wk) pre #3 · pending · 2027-07-30 — Q2 window check-in (50%) pre #2 · pending · 2028-01-01 — Regulatory framework for gene drive insect release proposed pre #1 · pending · 2028-03-14 — Q3 window check-in (75%) cascade #1 · pending · 2028-12-31 — First field/contained release of gene-drive screwworm cascade #2 · pending · 2029-03-17 — Measurable population suppression of screwworm in target zone pre #6 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #5 · pending · 2026-12-15 — Astromech reaches first paying customer or major partnership outside Colossal pre #4 · pending · 2027-05-01 — Astromech valuation step-up and Series B raise pre #3 · pending · 2027-05-02 — Colossal publishes peer-reviewed paper on its synthetic-biology modeling stack pre #2 · pending · 2027-08-01 — Form Bio platform reports cross-pharma adoption metrics pre #1 · pending · 2028-03-16 — Mammoth/thylacine de-extinction proof-of-concept embryo or birth cascade #1 · pending · 2030-04-18 — Dario Amodei will solve most/all neurological diseases by end of decade cascade #2 · pending · 2030-10-10 — Europa Clipper will arrive at Jupiter in 2030, conducting 50 passes near Europa. cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #4 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 cascade #5 · pending · 2063-06-21 — Peter's 14-year-old son Milan will never get a driver's license. pre #6 · pending · 2027-11-01 — IUCN formally endorses synthetic-biology assisted-evolution for conservation pre #5 · pending · 2028-03-16 — First gene-edited endangered animal released into wild monitored habitat pre #4 · pending · 2028-04-11 — Q2 window check-in (50%) pre #3 · pending · 2028-09-15 — Heat-tolerant coral or amphibian gene-edit deployed at reef/wetland scale pre #2 · pending · 2029-03-16 — Treaty-level framework on environmental release of edited organisms enters force pre #1 · pending · 2029-04-02 — Q3 window check-in (75%) pre #6 · hit · 2026-04-12 — Colossal publicly describes gene drive as reversible (rollback feature documented) pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2026-12-15 — Peer-reviewed publication on Colossal's reversible gene drive containment mechanism cascade #2 · pending · 2027-03-17 — Independent demonstration of rollback in caged trial cascade #3 · pending · 2027-03-17 — Critical scientific pushback (rebuttal paper questioning rollback feasibility) cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #5 · pending · 2027-08-01 — Regulatory approval (USDA APHIS / NZ EPA / Australia OGTR) for first wild-release pilot cascade #6 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. pre #6 · pending · 2028-07-01 — Second African nation re-permits gene-drive Anopheles trial pre #5 · pending · 2028-09-09 — Q1 window check-in (25%) pre #4 · pending · 2029-07-01 — First gene-drive eradication targeting an invasive species achieves measurable population suppression pre #3 · pending · 2030-07-02 — WHO/CBD adopts standardized gene-drive containment protocol distinguishing native vs invasive pre #2 · pending · 2031-01-21 — Q2 window check-in (50%) pre #1 · pending · 2033-06-02 — Q3 window check-in (75%) pre #6 · pending · 2026-11-29 — Colossal Biosciences announces second sovereign-state Biovault partnership (post-UAE) pre #5 · pending · 2027-02-21 — Q2 window check-in (50%) pre #4 · pending · 2027-05-02 — Dubai Museum of the Future BioVault facility opens to public visitors pre #3 · pending · 2027-05-02 — Colossal banks first 100 of the 10,000-species target pre #2 · pending · 2027-07-19 — Q3 window check-in (75%) pre #1 · pending · 2027-08-01 — Colossal Series D or pre-IPO financing round closes at >=$10B valuation cascade #1 · pending · 2028-01-01 — Third or more sovereign Biovault site under construction simultaneously (network confirmation) cascade #2 · pending · 2029-12-31 — First de-extinction or rewilded species sourced from BioVault genetic material pre #6 · pending · 2026-12-31 — Carbios Longlaville facility online (50K t/yr PET) pre #5 · pending · 2027-05-02 — Breaking secures Series A funding ≥$50M pre #4 · pending · 2027-09-01 — Q2 window check-in (50%) pre #3 · pending · 2028-03-16 — Breaking demonstrates pilot-scale facility for ≥1 non-PET plastic pre #2 · pending · 2028-05-03 — Q3 window check-in (75%) pre #1 · pending · 2028-09-15 — Independent benchmark confirms Breaking enzymes outperform PETase variants on rate/area pre #6 · pending · 2027-05-02 — First viable northern-white-rhino embryo transfer pregnancy maintained past 90 days in southern white rhino surrogate pre #5 · pending · 2027-08-19 — Q1 window check-in (25%) pre #4 · pending · 2028-06-15 — Functional oocytes from northern-white-rhino induced pluripotent stem cells produced (synthetic genetic diversity proof) pre #3 · pending · 2028-12-07 — Q2 window check-in (50%) pre #2 · pending · 2029-06-15 — First northern white rhino calf born from BioRescue embryo + southern white rhino surrogate pre #1 · pending · 2030-03-28 — Q3 window check-in (75%) cascade #1 · pending · 2031-07-18 — Synthetic-genetic-diversity engineering applied to NWR — first calf born with iPSC-derived gametes pre #6 · hit · 2026-04-14 — OpenAI x Novo Nordisk drug-discovery partnership announced (broader pharma platform) pre #5 · pending · 2027-03-21 — Q1 window check-in (25%) pre #4 · pending · 2028-02-10 — Q2 window check-in (50%) pre #3 · pending · 2028-03-31 — First repurposed off-patent compound from OpenAI program shows positive Alzheimer's biomarker signal pre #2 · pending · 2028-06-15 — First OpenAI-Foundation backed Alzheimer's drug candidate enters Phase 1 clinical trial pre #1 · pending · 2029-01-01 — Q3 window check-in (75%) cascade #1 · pending · 2030-07-02 — Spinout/IPO of any AI-pharma company launched from OpenAI Alzheimer's program crosses $10B valuation cascade #2 · pending · 2030-12-31 — First FDA approval of OpenAI-Foundation lineage Alzheimer's drug pre #6 · pending · 2026-12-15 — Arc Institute Virtual Cell Challenge 2026 results show >2x improvement over State baseline pre #5 · pending · 2027-03-17 — CZI rBio / TranscriptFormer next-gen model published with whole-cell perturbation prediction pre #4 · pending · 2027-03-17 — Nvidia or major cloud announces dedicated virtual-cell training compute partnership pre #3 · pending · 2028-01-01 — First peer-reviewed virtual-cell prediction validated wet-lab in independent academic study pre #2 · pending · 2028-02-09 — Stargate is a $500 billion multiyear capex program for distributed AI data-center construction (2025-2028, with Trump ad pre #1 · pending · 2029-06-15 — First FDA-acceptable in-silico virtual-cell experiment cited in IND submission cascade #1 · pending · 2031-06-16 — Cascade: First drug program with discovery anchor in virtual-cell simulation enters Phase 1 cascade #2 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve e cascade #6 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 pre #6 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #5 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #4 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) pre #3 · pending · 2027-05-02 — First E. coli whole-cell model with predictive accuracy on growth/metabolism published pre #2 · pending · 2028-06-15 — Compute time for 1 hour of cell biology drops from 6 days to <1 day pre #1 · pending · 2029-03-31 — First yeast (S. cerevisiae) whole-cell digital twin published cascade #1 · pending · 2030-07-31 — First mammalian (HeLa or hepatocyte) whole-cell simulation reaches publication cascade #2 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #3 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #4 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #5 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve e cascade #6 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 pre #4 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) pre #3 · pending · 2027-10-22 — Q1 window check-in (25%) pre #2 · pending · 2029-08-12 — Q2 window check-in (50%) pre #1 · pending · 2031-06-03 — Q3 window check-in (75%) cascade #1 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow. pre #6 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #5 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) pre #4 · pending · 2027-03-17 — Pharma AI R&D spend >75% increase YoY pre #3 · pending · 2028-12-31 — AI-driven biotech aging-reversal compound enters Phase 1 pre #2 · pending · 2030-07-02 — Multiple AI-designed drugs receive FDA approval pre #1 · pending · 2032-12-31 — Healthy life-expectancy gain exceeds 1 year per calendar year sustained cascade #1 · pending · 2034-06-16 — US life expectancy at birth crosses 90 years cascade #2 · pending · 2037-06-24 — Mass drivers on the moon will shoot AI satellites into deep space; self-sustaining lunar city will follow. cascade #3 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 cascade #4 · pending · 2046-07-24 — Combustion engines largely gone in 20 years but world will be very different pre #6 · pending · 2028-06-04 — Competitors that can match Figure's current capabilities are at least two years behind. pre #5 · pending · 2028-06-24 — AI will bulk-solve math, physical sciences, engineering, medicine, and material sciences. pre #4 · pending · 2028-07-01 — First AI-designed drug approved for any neurological indication pre #3 · pending · 2028-07-10 — For the next few years more people will end up doing more work, not less (996 turns into 997). pre #2 · pending · 2028-07-21 — Figure is effectively sold out on its current customer base for the next two to three years. pre #1 · pending · 2028-08-10 — Two years from now, best AI will not be freely accessible — it will be withheld citing security/safety. cascade #1 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #2 · pending · 2034-09-16 — Dragonfly nuclear-powered octicopter arrives at Titan in 2034. cascade #3 · pending · 2036-09-06 — Moon base will exist in 10 years cascade #4 · pending · 2039-09-22 — True artificial general intelligence will be achieved between 2032 and 2042 — 'first we solve AI, then use AI to solve e cascade #5 · pending · 2040-07-06 — TEPCO's restarted reactor will support 20% of Japan's electric needs by 2040 pre #6 · hit · 2025-06-30 — Insilico Medicine Phase IIa positive results (TNIK inhibitor for IPF) pre #5 · hit · 2026-02-01 — Industry analyst report confirms 80-90% AI-drug Phase 1 success rate pre #4 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #3 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2027-03-17 — First AI-designed drug enters Phase III pivotal trial cascade #2 · pending · 2027-05-02 — Isomorphic Labs first IsoDDE molecule enters clinical trials cascade #3 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #4 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. cascade #5 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #6 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. pre #6 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #5 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #4 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #3 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #2 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) pre #1 · pending · 2026-06-15 — First true n=1 personalized drug therapy approved cascade #1 · pending · 2026-12-16 — n>=10 documented n=1 AI-designed therapies in patients cascade #2 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #3 · pending · 2027-07-02 — AI-designed drug discovery time falls to <12 months consistently cascade #4 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. cascade #5 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #6 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. pre #6 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #5 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #4 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #3 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) pre #2 · overdue · 2026-05-27 — FDA Commissioner Makary departure, replacement, or announced leave pre #1 · overdue · 2026-05-27 — RFK Jr override of FDA decision becomes public or formal cascade #1 · pending · 2026-07-16 — Major FDA reorganization or RIF (reduction in force) announcement cascade #2 · pending · 2026-08-31 — Congressional hearing or bipartisan letter calls for FDA reform cascade #3 · pending · 2026-12-30 — Pharma industry lobbying for FDA leadership change escalates publicly cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #5 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. cascade #6 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human pre #6 · hit · 2025-05-21 — Inaugural Enhanced Games scheduled for May 21-24, 2026 Las Vegas pre #5 · hit · 2025-05-21 — Gkolomeev posts unofficial 50m freestyle world record (20.89s) in Enhanced trial pre #4 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #3 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2026-05-22 — Enhanced Games inaugural competition delivered without major safety incident cascade #2 · pending · 2026-05-22 — Enhanced 2026 produces >=2 records faster than current official world records cascade #3 · pending · 2027-01-30 — Enhanced Games announces second edition with year-over-year mark improvements cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #5 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. cascade #6 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2026-12-15 — Number of Neuralink human implants reaches 50+ cascade #2 · pending · 2026-12-31 — Neuralink launches high-volume production with automated surgery in 2026 cascade #3 · pending · 2026-12-31 — Neuralink Blindsight first patient trial begins (non-destructive read/write to cortex) cascade #4 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #5 · pending · 2027-07-02 — First whole-brain emulation / connectome scan published from preserved tissue cascade #6 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. pre #5 · hit · 2026-04-29 — Nvidia quadrupled chip production output while only doubling human headcount — achieved by deploying AI coding tools (Cu pre #4 · hit · 2026-04-29 — Training runs costing $10 billion for a single model will commence sometime in 2025. pre #3 · hit · 2026-04-29 — Anthropic revenue will cross OpenAI revenue in middle of 2026 pre #2 · hit · 2026-04-29 — 2025 will be the definitive year that agentic systems finally hit the mainstream. pre #1 · hit · 2026-04-29 — Recursive self-improvement is already happening now (no longer three years out) cascade #1 · pending · 2027-06-26 — Math is cooked (will be solved), physics cooked, biology char broiled. cascade #2 · pending · 2028-06-25 — We're exiting the industrial age permanently as recursive self-improvement unfolds. cascade #3 · pending · 2028-09-07 — By 2028, AI systems will reach 'independent researcher' level — driving autonomous scientific discoveries without human cascade #4 · pending · 2033-07-30 — Ray Kurzweil predicts Longevity Escape Velocity (LEV) by 2033. cascade #5 · pending · 2033-08-10 — ASI will arrive within 2 years to 5 years to this next decade target window end · today (amber dashed) · ✓/✗/◐ history strip = past resolutions · ghost arrows = evidence shift 40 plotted · click any dot for detail
Y-axis bands: 0–25 % red-tint (unlikely) · 25–75 % amber (uncertain) · 75–100 % green-tint (likely). Vertical amber dashed line = today. Each prediction sits at (its expected resolution date, its current probability). Probabilities are conditional on everything that has already happened — past hits/misses + recent intake updates feed into the LBP propagation that produced these values.